Mapping intact protein isoforms in discovery mode using top-down proteomics JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ... Nature 480 (7376), 254-258, 2011 | 784 | 2011 |
A protease for'middle-down'proteomics C Wu, JC Tran, L Zamdborg, KR Durbin, M Li, DR Ahlf, BP Early, ... Nature methods 9 (8), 822-824, 2012 | 193 | 2012 |
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence AD Catherman, KR Durbin, DR Ahlf, BP Early, RT Fellers, JC Tran, ... Molecular & Cellular Proteomics 12 (12), 3465-3473, 2013 | 189 | 2013 |
Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates PK Mahalingaiah, R Ciurlionis, KR Durbin, RL Yeager, BK Philip, B Bawa, ... Pharmacology & Therapeutics 200, 110-125, 2019 | 186 | 2019 |
Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes JO Kafader, RD Melani, KR Durbin, B Ikwuagwu, BP Early, RT Fellers, ... Nature methods 17 (4), 391-394, 2020 | 168 | 2020 |
Accurate sequence analysis of a monoclonal antibody by top-down and middle-down orbitrap mass spectrometry applying multiple ion activation techniques L Fornelli, K Srzentić, R Huguet, C Mullen, S Sharma, V Zabrouskov, ... Analytical chemistry 90 (14), 8421-8429, 2018 | 163 | 2018 |
Analysis of intact protein isoforms by mass spectrometry JD Tipton, JC Tran, AD Catherman, DR Ahlf, KR Durbin, NL Kelleher Journal of Biological Chemistry 286 (29), 25451-25458, 2011 | 136 | 2011 |
The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput JF Kellie, JC Tran, JE Lee, DR Ahlf, HM Thomas, I Ntai, AD Catherman, ... Molecular BioSystems 6 (9), 1532-1539, 2010 | 135 | 2010 |
Quantitation and identification of thousands of human proteoforms below 30 kDa KR Durbin, L Fornelli, RT Fellers, PF Doubleday, M Narita, NL Kelleher Journal of proteome research 15 (3), 976-982, 2016 | 125 | 2016 |
The first pilot project of the consortium for top‐down proteomics: a status report X Dang, J Scotcher, S Wu, RK Chu, N Tolić, I Ntai, PM Thomas, RT Fellers, ... Proteomics 14 (10), 1130-1140, 2014 | 121 | 2014 |
Size-sorting combined with improved nanocapillary liquid chromatography− mass spectrometry for identification of intact proteins up to 80 kDa A Vellaichamy, JC Tran, AD Catherman, JE Lee, JF Kellie, SMM Sweet, ... Analytical chemistry 82 (4), 1234-1244, 2010 | 117 | 2010 |
A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome JE Lee, JF Kellie, JC Tran, JD Tipton, AD Catherman, HM Thomas, ... Journal of the American Society for Mass Spectrometry 20, 2183-2191, 2009 | 114 | 2009 |
Advancing top-down analysis of the human proteome using a benchtop quadrupole-orbitrap mass spectrometer L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ... Journal of proteome research 16 (2), 609-618, 2017 | 96 | 2017 |
Top down proteomics of human membrane proteins from enriched mitochondrial fractions AD Catherman, M Li, JC Tran, KR Durbin, PD Compton, BP Early, ... Analytical chemistry 85 (3), 1880-1888, 2013 | 90 | 2013 |
An informatic framework for decoding protein complexes by top-down mass spectrometry OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ... Nature methods 13 (3), 237-240, 2016 | 79 | 2016 |
Kinetics of re-establishing H3K79 methylation marks in global human chromatin SMM Sweet, M Li, PM Thomas, KR Durbin, NL Kelleher Journal of Biological Chemistry 285 (43), 32778-32786, 2010 | 76 | 2010 |
Thorough performance evaluation of 213 nm ultraviolet photodissociation for top-down proteomics L Fornelli, K Srzentić, TK Toby, PF Doubleday, R Huguet, C Mullen, ... Molecular & Cellular Proteomics 19 (2), 405-420, 2020 | 69 | 2020 |
STORI plots enable accurate tracking of individual ion signals JO Kafader, SC Beu, BP Early, RD Melani, KR Durbin, V Zabrouskov, ... Journal of The American Society for Mass Spectrometry 30, 2200-2203, 2019 | 67 | 2019 |
Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry JF Kellie, AD Catherman, KR Durbin, JC Tran, JD Tipton, JL Norris, ... Analytical chemistry 84 (1), 209-215, 2012 | 67 | 2012 |
Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation KR Durbin, OS Skinner, RT Fellers, NL Kelleher Journal of the American Society for Mass Spectrometry 26 (5), 782-787, 2015 | 61 | 2015 |