Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities S Heinz, C Benner, N Spann, E Bertolino, YC Lin, P Laslo, JX Cheng, ... Molecular cell 38 (4), 576-589, 2010 | 12516 | 2010 |
The selection and function of cell type-specific enhancers S Heinz, CE Romanoski, C Benner, CK Glass Nature reviews Molecular cell biology 16 (3), 144-154, 2015 | 1074 | 2015 |
Genome evolution in the allotetraploid frog Xenopus laevis AM Session, Y Uno, T Kwon, JA Chapman, A Toyoda, S Takahashi, ... Nature 538 (7625), 336-343, 2016 | 1003 | 2016 |
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ... Molecular cell 51 (3), 310-325, 2013 | 731 | 2013 |
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription MTY Lam, H Cho, HP Lesch, D Gosselin, S Heinz, Y Tanaka-Oishi, ... Nature 498 (7455), 511-515, 2013 | 603 | 2013 |
A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate YC Lin, S Jhunjhunwala, C Benner, S Heinz, E Welinder, R Mansson, ... Nature immunology 11 (7), 635-643, 2010 | 560 | 2010 |
Transcription elongation can affect genome 3D structure S Heinz, L Texari, MGB Hayes, M Urbanowski, MW Chang, N Givarkes, ... Cell 174 (6), 1522-1536. e22, 2018 | 433 | 2018 |
Effect of natural genetic variation on enhancer selection and function S Heinz, CE Romanoski, C Benner, KA Allison, MU Kaikkonen, ... Nature 503 (7477), 487-492, 2013 | 367 | 2013 |
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ... Immunity 51 (4), 655-670. e8, 2019 | 329 | 2019 |
Biomimetic morphogenesis of fluorapatite‐gelatin composites: Fractal growth, the question of intrinsic electric fields, core/shell assemblies, hollow spheres and reorganization … S Busch, H Dolhaine, A DuChesne, S Heinz, O Hochrein, F Laeri, ... European Journal of Inorganic Chemistry 1999 (10), 1643-1653, 1999 | 312 | 1999 |
Global changes in the nuclear positioning of genes and intra-and interdomain genomic interactions that orchestrate B cell fate YC Lin, C Benner, R Mansson, S Heinz, K Miyazaki, M Miyazaki, ... Nature immunology 13 (12), 1196-1204, 2012 | 308 | 2012 |
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages WQ Fan, H Morinaga, JJ Kim, E Bae, NJ Spann, S Heinz, CK Glass, ... The EMBO journal 29 (24), 4223-4236, 2010 | 273 | 2010 |
Species-specific regulation of Toll-like receptor 3 genes in men and mice S Heinz, V Haehnel, M Karaghiosoff, L Schwarzfischer, M Muller, ... Journal of Biological Chemistry 278 (24), 21502-21509, 2003 | 255 | 2003 |
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease HY Ma, G Yamamoto, J Xu, X Liu, D Karin, JY Kim, LB Alexandrov, ... Journal of hepatology 72 (5), 946-959, 2020 | 172 | 2020 |
Human promoters are intrinsically directional SHC Duttke, SA Lacadie, MM Ibrahim, CK Glass, DL Corcoran, C Benner, ... Molecular cell 57 (4), 674-684, 2015 | 169 | 2015 |
Identification of lineage-specific transcription factors that prevent activation of hepatic stellate cells and promote fibrosis resolution X Liu, J Xu, S Rosenthal, L Zhang, R McCubbin, N Meshgin, L Shang, ... Gastroenterology 158 (6), 1728-1744. e14, 2020 | 167 | 2020 |
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation A Rialdi, L Campisi, N Zhao, AC Lagda, C Pietzsch, JSY Ho, ... Science 352 (6289), aad7993, 2016 | 165 | 2016 |
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes L Escoubet-Lozach, C Benner, MU Kaikkonen, J Lozach, S Heinz, ... PLoS genetics 7 (12), e1002401, 2011 | 162 | 2011 |
Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells M Leddin, C Perrod, M Hoogenkamp, S Ghani, S Assi, S Heinz, ... Blood, The Journal of the American Society of Hematology 117 (10), 2827-2838, 2011 | 148 | 2011 |
Macrophage development from HSCs requires PU. 1-coordinated microRNA expression S Ghani, P Riemke, J Schönheit, D Lenze, J Stumm, M Hoogenkamp, ... Blood, The Journal of the American Society of Hematology 118 (8), 2275-2284, 2011 | 146 | 2011 |