Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440 GJ Bentley, N Narayanan, RK Jha, D Salvachúa, JR Elmore, GL Peabody, ... Metabolic engineering 59, 64-75, 2020 | 116 | 2020 |
Computational design of a PAK1 binding protein RK Jha, A Leaver-Fay, S Yin, Y Wu, GL Butterfoss, T Szyperski, ... Journal of molecular biology 400 (2), 257-270, 2010 | 91 | 2010 |
Scaling behavior and structure of denatured proteins F Ding, RK Jha, NV Dokholyan Structure 13 (7), 1047-1054, 2005 | 89 | 2005 |
Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin: Metabolic Tools for Enhanced Algal Fitness in the Prominent Order Prymnesiales … BT Hovde, CR Deodato, HM Hunsperger, SA Ryken, W Yost, RK Jha, ... PLoS Genetics 11 (9), e1005469, 2015 | 75 | 2015 |
Engineering an Acinetobacter regulon for biosensing and high-throughput enzyme screening in E. coli via flow cytometry RK Jha, TL Kern, DT Fox, CE M. Strauss Nucleic acids research 42 (12), 8150-8160, 2014 | 75 | 2014 |
Rosetta comparative modeling for library design: engineering alternative inducer specificity in a transcription factor RK Jha, S Chakraborti, TL Kern, DT Fox, CEM Strauss Proteins: Structure, Function, and Bioinformatics 83 (7), 1327-1340, 2015 | 72 | 2015 |
Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1 I Pardo, RK Jha, RE Bermel, F Bratti, M Gaddis, E McIntyre, W Michener, ... Metabolic engineering 62, 260-274, 2020 | 62 | 2020 |
A pangenomic analysis of the Nannochloropsisorganellar genomes reveals novel genetic variations in key metabolic genes SR Starkenburg, KJ Kwon, RK Jha, C McKay, M Jacobs, O Chertkov, ... BMC genomics 15, 1-21, 2014 | 54 | 2014 |
A protocatechuate biosensor for Pseudomonas putida KT2440 via promoter and protein evolution RK Jha, JM Bingen, CW Johnson, TL Kern, P Khanna, DS Trettel, ... Metabolic engineering communications 6, 33-38, 2018 | 46 | 2018 |
A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor RK Jha, TL Kern, Y Kim, C Tesar, R Jedrzejczak, A Joachimiak, ... Nucleic Acids Research 44 (17), 8490-8500, 2016 | 37 | 2016 |
The mitochondrial and chloroplast genomes of the haptophyte Chrysochromulina tobin contain unique repeat structures and gene profiles BT Hovde, SR Starkenburg, HM Hunsperger, LD Mercer, CR Deodato, ... BMC genomics 15, 1-23, 2014 | 36 | 2014 |
Sensor-enabled alleviation of product inhibition in chorismate pyruvate-lyase RK Jha, N Narayanan, N Pandey, JM Bingen, TL Kern, CW Johnson, ... ACS synthetic biology 8 (4), 775-786, 2019 | 31 | 2019 |
Scintillation Proximity Assay for Inhibitors of Escherichia coli MurG and, Optionally, MraY S Ravishankar, VP Kumar, B Chandrakala, RK Jha, SM Solapure, ... Antimicrobial agents and chemotherapy 49 (4), 1410-1418, 2005 | 29 | 2005 |
An improved Protein G with higher affinity for human/rabbit IgG Fc domains exploiting a computationally designed polar network RK Jha, T Gaiotto, ARM Bradbury, CEM Strauss Protein Engineering, Design & Selection 27 (4), 127-134, 2014 | 26 | 2014 |
A High-Throughput Screening Assay for Simultaneous Selection of Inhibitors of Mycobacterium tuberculosis 1-Deoxy-D-Xylulose-5-Phosphate Synthase (Dxs) or 1 … V Humnabadkar, RK Jha, N Ghatnekar, SM De Sousa Journal of Biomolecular Screening 16 (3), 303-312, 2011 | 20 | 2011 |
3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers RK Jha, CEM Strauss Cellular Logistics 2 (2), 69-77, 2012 | 18 | 2012 |
Rapid Thermostabilization of Bacillus thuringiensis Serovar Konkukian 97–27 Dehydroshikimate Dehydratase through a Structure-Based Enzyme Design and … LB Harrington, RK Jha, TL Kern, EN Schmidt, GM Canales, KB Finney, ... ACS synthetic biology 6 (1), 120-129, 2017 | 17 | 2017 |
Combined computational design of a zinc binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin binding BS Der, RK Jha, SM Lewis, PM Thompson, G Guntas, B Kuhlman Proteins: Structure, Function and Bioinformatics, 2013 | 17 | 2013 |
Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications RK Jha, YI Wu, JS Zawistowski, C MacNevin, KM Hahn, B Kuhlman Journal of molecular biology 413 (2), 513-522, 2011 | 16 | 2011 |
Identifying key determinants and dynamics of SARS-CoV-2/ACE2 tight interaction VA Ngo, RK Jha PLoS One 16 (9), e0257905, 2021 | 10 | 2021 |