A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4762 | 2020 |
The global phosphorylation landscape of SARS-CoV-2 infection M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ... Cell 182 (3), 685-712. e19, 2020 | 960 | 2020 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 686 | 2020 |
Evolution of enhanced innate immune evasion by SARS-CoV-2 LG Thorne, M Bouhaddou, AK Reuschl, L Zuliani-Alvarez, B Polacco, ... Nature 602 (7897), 487-495, 2022 | 434 | 2022 |
Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses R Wang, CR Simoneau, J Kulsuptrakul, M Bouhaddou, KA Travisano, ... Cell 184 (1), 106-119. e14, 2021 | 378 | 2021 |
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ... Science 371 (6532), 926-931, 2021 | 332 | 2021 |
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena, M Laporte, RL Pearl, ... Cell host & microbe 30 (3), 373-387. e7, 2022 | 169 | 2022 |
A protein interaction landscape of breast cancer M Kim, J Park, M Bouhaddou, K Kim, A Rojc, M Modak, M Soucheray, ... Science 374 (6563), eabf3066, 2021 | 118 | 2021 |
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... Research square, 2021 | 82 | 2021 |
Drug response consistency in CCLE and CGP M Bouhaddou, MS DiStefano, EA Riesel, E Carrasco, HY Holzapfel, ... Nature 540 (7631), E9-E10, 2016 | 82 | 2016 |
A comparison of mRNA sequencing with random primed and 3′-directed libraries Y Xiong, M Soumillon, J Wu, J Hansen, B Hu, JG Van Hasselt, ... Scientific reports 7 (1), 14626, 2017 | 69 | 2017 |
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling AS Mendiola, Z Yan, K Dixit, JR Johnson, M Bouhaddou, A Meyer-Franke, ... Nature immunology 24 (7), 1173-1187, 2023 | 64 | 2023 |
A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens M Bouhaddou, AM Barrette, AD Stern, RJ Koch, MS DiStefano, EA Riesel, ... PLoS computational biology 14 (3), e1005985, 2018 | 63 | 2018 |
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis T Kehrer, A Cupic, C Ye, S Yildiz, M Bouhaddou, NA Crossland, ... Cell Host & Microbe 31 (10), 1668-1684. e12, 2023 | 58 | 2023 |
SARS-CoV-2 variants evolve convergent strategies to remodel the host response M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ... Cell 186 (21), 4597-4614. e26, 2023 | 57 | 2023 |
A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity DL Swaney, DJ Ramms, Z Wang, J Park, Y Goto, M Soucheray, N Bhola, ... Science 374 (6563), eabf2911, 2021 | 56 | 2021 |
The landscape of human cancer proteins targeted by SARS-CoV-2 B Tutuncuoglu, M Cakir, J Batra, M Bouhaddou, M Eckhardt, DE Gordon, ... Cancer discovery 10 (7), 916-921, 2020 | 49 | 2020 |
A functional map of HIV-host interactions in primary human T cells J Hiatt, JF Hultquist, MJ McGregor, M Bouhaddou, RT Leenay, LM Simons, ... Nature communications 13 (1), 1752, 2022 | 41 | 2022 |
Engineered mammalian RNAi can elicit antiviral protection that negates the requirement for the interferon response AA Benitez, LA Spanko, M Bouhaddou, D Sachs, B Robert tenOever Cell reports 13 (7), 1456-1466, 2015 | 40 | 2015 |
Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B. 1.1. 7 variant AK Reuschl, LG Thorne, L Zuliani-Alvarez, M Bouhaddou, K Obernier, ... BioRxiv, 2021 | 37 | 2021 |