| The history of nanoscience and nanotechnology: from chemical–physical applications to nanomedicine S Bayda, M Adeel, T Tuccinardi, M Cordani, F Rizzolio Molecules 25 (1), 112, 2019 | 2098 | 2019 |
| Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells C Granchi, S Roy, C Giacomelli, M Macchia, T Tuccinardi, A Martinelli, ... Journal of medicinal chemistry 54 (6), 1599-1612, 2011 | 275 | 2011 |
| What is the current value of MM/PBSA and MM/GBSA methods in drug discovery? T Tuccinardi Expert opinion on drug discovery 16 (11), 1233-1237, 2021 | 170 | 2021 |
| Application of MM-PBSA methods in virtual screening G Poli, C Granchi, F Rizzolio, T Tuccinardi Molecules 25 (8), 1971, 2020 | 151 | 2020 |
| Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors E Nuti, T Tuccinardi, A Rossello Current pharmaceutical design 13 (20), 2087-2100, 2007 | 143 | 2007 |
| Cannabinoid CB2/CB1 selectivity. Receptor modeling and automated docking analysis T Tuccinardi, PL Ferrarini, C Manera, G Ortore, G Saccomanni, ... Journal of medicinal chemistry 49 (3), 984-994, 2006 | 141 | 2006 |
| CDK inhibitors: from the bench to clinical trials F Rizzolio, T Tuccinardi, I Caligiuri, C Lucchetti, A Giordano Current drug targets 11 (3), 279-290, 2010 | 118 | 2010 |
| Extensive consensus docking evaluation for ligand pose prediction and virtual screening studies T Tuccinardi, G Poli, V Romboli, A Giordano, A Martinelli Journal of Chemical Information and Modeling 54 (10), 2980-2986, 2014 | 116 | 2014 |
| Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor CH Wong, L Nguyen, J Peh, LM Luu, JS Sanchez, SL Richardson, ... Journal of the American Chemical Society 136 (17), 6355-6361, 2014 | 115 | 2014 |
| Former Foodstuff Products in Tenebrio Molitor Rearing: Effects on Growth, Chemical Composition, Microbiological Load, and Antioxidant Status S Mancini, F Fratini, B Turchi, S Mattioli, A Dal Bosco, T Tuccinardi, ... Animals 9 (8), 484, 2019 | 113 | 2019 |
| Docking-based virtual screening: recent developments T Tuccinardi Combinatorial chemistry & high throughput screening 12 (3), 303-314, 2009 | 112 | 2009 |
| The TRPA 1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives R Nassini, C Fusi, S Materazzi, E Coppi, T Tuccinardi, IM Marone, ... British journal of pharmacology 172 (13), 3397-3411, 2015 | 109 | 2015 |
| The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: interplay with the complex tumor microenvironment and novel therapeutic strategies B El Hassouni, C Granchi, A Vallés-Martí, IGP Supadmanaba, G Bononi, ... Seminars in cancer biology 60, 238-248, 2020 | 102 | 2020 |
| Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl … T Tuccinardi, A Martinelli, E Nuti, P Carelli, F Balzano, G Uccello-Barretta, ... Bioorganic & medicinal chemistry 14 (12), 4260-4276, 2006 | 100 | 2006 |
| α-Glucosidase and α-Amylase Inhibitors from Arcytophyllum thymifolium L Milella, S Milazzo, M De Leo, MB Vera Saltos, I Faraone, T Tuccinardi, ... Journal of Natural Products 79 (8), 2104-2112, 2016 | 98 | 2016 |
| New 1, 8-naphthyridine and quinoline derivatives as CB2 selective agonists C Manera, MG Cascio, V Benetti, M Allarà, T Tuccinardi, A Martinelli, ... Bioorganic & medicinal chemistry letters 17 (23), 6505-6510, 2007 | 95 | 2007 |
| Design, synthesis, and biological evaluation of new 1, 8-naphthyridin-4 (1 H)-on-3-carboxamide and quinolin-4 (1 H)-on-3-carboxamide derivatives as CB2 selective agonists C Manera, V Benetti, MP Castelli, T Cavallini, S Lazzarotti, F Pibiri, ... Journal of medicinal chemistry 49 (20), 5947-5957, 2006 | 92 | 2006 |
| Proposal of a new binding orientation for non-peptide AT1 antagonists: Homology modeling, docking and three-dimensional quantitative structure− activity relationship analysis T Tuccinardi, V Calderone, S Rapposelli, A Martinelli Journal of medicinal chemistry 49 (14), 4305-4316, 2006 | 89 | 2006 |
| The extra-virgin olive oil polyphenols oleocanthal and oleacein counteract inflammation-related gene and miRNA expression in adipocytes by attenuating NF-κB activation S Carpi, E Scoditti, M Massaro, B Polini, C Manera, M Digiacomo, ... Nutrients 11 (12), 2855, 2019 | 87 | 2019 |
| Continued exploration of 1, 2, 4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX … M Krasavin, A Shetnev, T Sharonova, S Baykov, S Kalinin, A Nocentini, ... European Journal of Medicinal Chemistry 164, 92-105, 2019 | 85 | 2019 |
