Icaritin exacerbates mitophagy and synergizes with doxorubicin to induce immunogenic cell death in hepatocellular carcinoma Z Yu, J Guo, M Hu, Y Gao, L Huang Acs Nano 14 (4), 4816-4828, 2020 | 315 | 2020 |
Gold nanoparticles enlighten the future of cancer theranostics J Guo, K Rahme, Y He, LL Li, JD Holmes, CM O’Driscoll International journal of nanomedicine, 6131-6152, 2017 | 300 | 2017 |
Nano codelivery of oxaliplatin and folinic acid achieves synergistic chemo-immunotherapy with 5-fluorouracil for colorectal cancer and liver metastasis J Guo, Z Yu, M Das, L Huang ACS nano 14 (4), 5075-5089, 2020 | 184 | 2020 |
Can non-viral technologies knockdown the barriers to siRNA delivery and achieve the next generation of cancer therapeutics? J Guo, L Bourre, DM Soden, GC O'Sullivan, C O'Driscoll Biotechnology advances 29 (4), 402-417, 2011 | 151 | 2011 |
Anisamide-targeted cyclodextrin nanoparticles for siRNA delivery to prostate tumours in mice J Guo, JR Ogier, S Desgranges, R Darcy, C O’Driscoll Biomaterials 33 (31), 7775-7784, 2012 | 149 | 2012 |
Therapeutic targeting in the silent era: advances in non-viral siRNA delivery J Guo, KA Fisher, R Darcy, JF Cryan, C O’Driscoll Molecular Biosystems 6 (7), 1143-1161, 2010 | 135 | 2010 |
The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics KA Fitzgerald, J Guo, EG Tierney, CM Curtin, M Malhotra, R Darcy, ... Biomaterials 66, 53-66, 2015 | 129 | 2015 |
A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer D Sun, Y Zou, L Song, S Han, H Yang, D Chu, Y Dai, J Ma, CM O'Driscoll, ... Acta Pharmaceutica Sinica B 12 (1), 378-393, 2022 | 123 | 2022 |
Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma J Guo, Z Yu, D Sun, Y Zou, Y Liu, L Huang Molecular Cancer 20, 1-17, 2021 | 120 | 2021 |
Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs BT Griffin, J Guo, E Presas, MD Donovan, MJ Alonso, CM O'Driscoll Advanced Drug Delivery Reviews 106, 367-380, 2016 | 108 | 2016 |
Systemic delivery of therapeutic small interfering RNA using a pH-triggered amphiphilic poly-L-lysine nanocarrier to suppress prostate cancer growth in mice J Guo, WP Cheng, J Gu, C Ding, X Qu, Z Yang, C O’Driscoll European Journal of Pharmaceutical Sciences 45 (5), 521-532, 2012 | 102 | 2012 |
Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategies Y Liu, J Guo, L Huang Theranostics 10 (7), 3099-3117, 2020 | 100 | 2020 |
Bioconjugated gold nanoparticles enhance cellular uptake: A proof of concept study for siRNA delivery in prostate cancer cells J Guo, CM O’Driscoll, JD Holmes, K Rahme International journal of pharmaceutics 509 (1-2), 16-27, 2016 | 86 | 2016 |
Modulation of macrophages by a paeoniflorin-loaded hyaluronic acid-based hydrogel promotes diabetic wound healing H Yang, L Song, B Sun, D Chu, L Yang, M Li, H Li, Y Dai, Z Yu, J Guo Materials Today Bio 12, 100139, 2021 | 84 | 2021 |
Mechanistic studies on the uptake and intracellular trafficking of novel cyclodextrin transfection complexes by intestinal epithelial cells MJ O’Neill, J Guo, C Byrne, R Darcy, CM O’Driscoll International journal of pharmaceutics 413 (1-2), 174-183, 2011 | 82 | 2011 |
d-lactate modulates M2 tumor-associated macrophages and remodels immunosuppressive tumor microenvironment for hepatocellular carcinoma S Han, X Bao, Y Zou, L Wang, Y Li, L Yang, A Liao, X Zhang, X Jiang, ... Science Advances 9 (29), eadg2697, 2023 | 81 | 2023 |
Role of hyaluronic acids and potential as regenerative biomaterials in wound healing H Yang, L Song, Y Zou, D Sun, L Wang, Z Yu, J Guo ACS Applied Bio Materials 4 (1), 311-324, 2020 | 79 | 2020 |
Tackling TAMs for cancer immunotherapy: it’s nano time Y Yang, J Guo, L Huang Trends in pharmacological sciences 41 (10), 701-714, 2020 | 79 | 2020 |
A low molecular weight hyaluronic acid derivative accelerates excisional wound healing by modulating pro-inflammation, promoting epithelialization and neovascularization, and … Y Gao, Y Sun, H Yang, P Qiu, Z Cong, Y Zou, L Song, J Guo, ... International journal of molecular sciences 20 (15), 3722, 2019 | 78 | 2019 |
Bufalin stimulates antitumor immune response by driving tumor-infiltrating macrophage toward M1 phenotype in hepatocellular carcinoma Z Yu, Y Li, Y Li, J Zhang, M Li, L Ji, Y Tang, Y Zheng, J Sheng, Q Han, F Li, ... Journal for Immunotherapy of Cancer 10 (5), 2022 | 75 | 2022 |