| Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase LA Tintignac, J Lagirand, S Batonnet, V Sirri, MP Leibovitch, ... Journal of Biological Chemistry 280 (4), 2847-2856, 2005 | 524 | 2005 |
| Protein kinase B/Akt at a glance E Fayard, LA Tintignac, A Baudry, BA Hemmings Journal of cell science 118 (24), 5675-5678, 2005 | 461 | 2005 |
| Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting LA Tintignac, HR Brenner, MA Rüegg Physiological reviews, 2015 | 434 | 2015 |
| The initiation factor eIF3‐f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy J Lagirand‐Cantaloube, N Offner, A Csibi, MP Leibovitch, ... The EMBO journal 27 (8), 1266-1276, 2008 | 383 | 2008 |
| PKB and the mitochondria: AKTing on apoptosis A Parcellier, LA Tintignac, E Zhuravleva, BA Hemmings Cellular signalling 20 (1), 21-30, 2008 | 296 | 2008 |
| Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy P Castets, S Lin, N Rion, S Di Fulvio, K Romanino, M Guridi, S Frank, ... Cell metabolism 17 (5), 731-744, 2013 | 295 | 2013 |
| Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV‐1 envelope M Castedo, T Roumier, J Blanco, KF Ferri, J Barretina, LA Tintignac, ... The EMBO journal, 2002 | 185 | 2002 |
| Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy CF Bentzinger, S Lin, K Romanino, P Castets, M Guridi, S Summermatter, ... Skeletal muscle 3, 1-16, 2013 | 167 | 2013 |
| The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse A Csibi, K Cornille, MP Leibovitch, A Poupon, LA Tintignac, AMJ Sanchez, ... PloS one 5 (2), e8994, 2010 | 153 | 2010 |
| The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia DJ Ham, A Börsch, S Lin, M Thürkauf, M Weihrauch, JR Reinhard, ... Nature communications 11 (1), 4510, 2020 | 145 | 2020 |
| MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines A Csibi, MP Leibovitch, K Cornille, LA Tintignac, SA Leibovitch Journal of Biological Chemistry 284 (7), 4413-4421, 2009 | 129 | 2009 |
| Stabilization of MyoD by direct binding to p57Kip2 EG Reynaud, MP Leibovitch, LAJ Tintignac, K Pelpel, M Guillier, ... Journal of Biological Chemistry 275 (25), 18767-18776, 2000 | 127 | 2000 |
| Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21 M Guridi, LA Tintignac, S Lin, B Kupr, P Castets, MA Rüegg Science signaling 8 (402), ra113-ra113, 2015 | 112 | 2015 |
| Cyclin E–Cdk2 Phosphorylation Promotes Late G1-Phase Degradation of MyoD in Muscle Cells LA Tintignac, MP Leibovitch, M Kitzmann, A Fernandez, B Ducommun, ... Experimental cell research 259 (1), 300-307, 2000 | 80 | 2000 |
| Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia A Börsch, DJ Ham, N Mittal, LA Tintignac, E Migliavacca, JN Feige, ... Communications Biology 4 (1), 194, 2021 | 61 | 2021 |
| mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis L Mazelin, B Panthu, AS Nicot, E Belotti, L Tintignac, G Teixeira, Q Zhang, ... Journal of molecular and cellular cardiology 97, 213-225, 2016 | 58 | 2016 |
| Myostatin inactivation increases myotube size through regulation of translational initiation machinery J Rodriguez, B Vernus, M Toubiana, E Jublanc, L Tintignac, S Leibovitch, ... Journal of cellular biochemistry 112 (12), 3531-3542, 2011 | 57 | 2011 |
| Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle DJ Ham, A Börsch, K Chojnowska, S Lin, AB Leuchtmann, AS Ham, ... Nature communications 13 (1), 2025, 2022 | 56 | 2022 |
| Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism M Guridi, B Kupr, K Romanino, S Lin, D Falcetta, L Tintignac, MA Rüegg Skeletal muscle 6, 1-14, 2016 | 53 | 2016 |
| Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry LAJ Tintignac, V Sirri, MP Leibovitch, Y Lécluse, M Castedo, D Metivier, ... Molecular and cellular biology, 2004 | 53 | 2004 |
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