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Mykhailo Girych
Mykhailo Girych
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Antidepressant drugs act by directly binding to TRKB neurotrophin receptors
PC Casarotto, M Girych, SM Fred, V Kovaleva, R Moliner, G Enkavi, ...
Cell 184 (5), 1299-1313. e19, 2021
5252021
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
R Moliner, M Girych, CA Brunello, V Kovaleva, C Biojone, G Enkavi, ...
Nature Neuroscience 26 (6), 1032-1041, 2023
2502023
Molecular electrometer and binding of cations to phospholipid bilayers
A Catte, M Girych, M Javanainen, C Loison, J Melcr, MS Miettinen, ...
Physical Chemistry Chemical Physics 18 (47), 32560-32569, 2016
942016
Combined thioflavin T–Congo red fluorescence assay for amyloid fibril detection
M Girych, G Gorbenko, I Maliyov, V Trusova, C Mizuguchi, H Saito, ...
Methods and applications in fluorescence 4 (3), 034010, 2016
562016
Mechanistic Understanding from Molecular Dynamics in Pharmaceutical Research 2: Lipid Membrane in Drug Design
T Róg, M Girych, A Bunker
Pharmaceuticals 14 (10), 1062, 2021
412021
Interaction of thioflavin T with amyloid fibrils of apolipoprotein AI N-terminal fragment: resonance energy transfer study
M Girych, G Gorbenko, V Trusova, E Adachi, C Mizuguchi, K Nagao, ...
Journal of structural biology 185 (1), 116-124, 2014
362014
Cyanine dyes derived inhibition of insulin fibrillization
K Vus, M Girych, V Trusova, G Gorbenko, A Kurutos, A Vasilev, N Gadjev, ...
Journal of Molecular Liquids 276, 541-552, 2019
352019
Cholesterol recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: the case for TRKB
C Cannarozzo, SM Fred, M Girych, C Biojone, G Enkavi, T Róg, ...
BioRxiv, 734012, 2020
282020
TrkB transmembrane domain: bridging structural understanding with therapeutic strategy
G Enkavi, M Girych, R Moliner, I Vattulainen, E Castrén
Trends in Biochemical Sciences, 2024
142024
FRET evidence for untwisting of amyloid fibrils on the surface of model membranes
G Gorbenko, V Trusova, M Girych, E Adachi, C Mizuguchi, K Akaji, H Saito
Soft matter 11 (31), 6223-6234, 2015
142015
Spectroscopic and molecular docking studies of the interactions of monomeric unsymmetrical polycationic fluorochromes with DNA and RNA
O Zhytniakivska, M Girych, V Trusova, G Gorbenko, A Vasilev, ...
Dyes and Pigments, 108446, 2020
122020
Membrane effects of N-terminal fragment of apolipoprotein AI: a fluorescent probe study
V Trusova, G Gorbenko, M Girych, E Adachi, C Mizuguchi, R Sood, ...
Journal of fluorescence 25 (2), 253-261, 2015
112015
Maturation of the SARS-CoV-2 virus is regulated by dimerization of its main protease
S Kaptan, M Girych, G Enkavi, W Kulig, V Sharma, J Vuorio, T Rog, ...
Computational and Structural Biotechnology Journal 20, 3336-3346, 2022
102022
Antidepressants act by binding to the cholesterol-interaction site at TRKB neurotrophin receptor
PC Casarotto, M Girych, SM Fred, R Moliner, G Enkavi, C Biojone, ...
bioRxiv, 757989, 2019
102019
Fluorescence study of the effect of the oxidized phospholipids on amyloid fibril formation by the apolipoprotein AI N-terminal fragment
K Vus, M Girych, V Trusova, G Gorbenko, P Kinnunen, C Mizuguchi, ...
Chemical Physics Letters 688, 1-6, 2017
82017
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)
M Girych, W Kulig, G Enkavi, I Vattulainen
Cold Spring Harbor Perspectives in Biology 15 (10), a041419, 2023
72023
Interactions of lipid membranes with fibrillar protein aggregates
G Gorbenko, V Trusova, M Girych, E Adachi, C Mizuguchi, H Saito
Lipids in Protein Misfolding, 135-155, 2015
72015
Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting
JHA Clubb, TV Kudling, M Girych, L Haybout, S Pakola, F Hamdan, ...
Frontiers in Immunology 14, 1060540, 2023
52023
Association of novel benzanthrone dyes with amyloid fibrils: A resonance energy transfer study
K Vus, M Girych, G Gorbenko, P Kinnunen, E Kirilova, G Kirilov, E Adachi, ...
Вісник Львівського університету. Серія біологічна, 189-196, 2014
32014
Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling
BG Abraham, T Haikarainen, J Vuorio, M Girych, AT Virtanen, A Kurttila, ...
Science Advances 10 (10), eadl2097, 2024
22024
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