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Si-Jie (SJ) Chen
Si-Jie (SJ) Chen
Other namesSijie Chen
Senior Principal Investigator, BeiGene (Guangzhou) Innovation Center
Verified email at beigene.com - Homepage
Title
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Cited by
Year
Copper-catalysed benzylic C–H coupling with alcohols via radical relay enabled by redox buffering
H Hu, SJ Chen, M Mandal, SM Pratik, JA Buss, SW Krska, CJ Cramer, ...
Nature catalysis 3 (4), 358-367, 2020
1482020
Site-selective copper-catalyzed azidation of benzylic C–H bonds
SE Suh, SJ Chen, M Mandal, IA Guzei, CJ Cramer, SS Stahl
Journal of the American Chemical Society 142 (26), 11388-11393, 2020
1412020
Copper-Catalyzed Cross-Coupling of Benzylic C–H Bonds and Azoles with Controlled N-Site Selectivity
SJ Chen, DL Golden, SW Krska, SS Stahl
Journal of the American Chemical Society 143 (36), 14438-14444, 2021
522021
Benzylic C–H esterification with limiting C–H substrate enabled by photochemical redox buffering of the Cu catalyst
DL Golden, C Zhang, SJ Chen, A Vasilopoulos, IA Guzei, SS Stahl
Journal of the American Chemical Society 145 (17), 9434-9440, 2023
372023
Uncanonical semireduction of quinolines and isoquinolines via regioselective HAT-promoted hydrosilylation
C Hu, C Vo, RR Merchant, SJ Chen, JME Hughes, BK Peters, T Qin
Journal of the American Chemical Society 145 (1), 25-31, 2022
192022
Programmable late-stage functionalization of bridge-substituted bicyclo [1.1. 1] pentane bis-boronates
Y Yang, J Tsien, R Dykstra, SJ Chen, JB Wang, RR Merchant, ...
Nature chemistry 16 (2), 285-293, 2024
162024
Copper-Catalyzed Benzylic C–H Cross-Coupling Enabled by Redox Buffers: Expanding Synthetic Access to Three-Dimensional Chemical Space
SJ Chen, SW Krska, SS Stahl
Accounts of chemical research 56 (24), 3604-3615, 2023
152023
Accessing three-dimensional molecular diversity through benzylic C–H cross-coupling
SJ Chen, CQ He, M Kong, J Wang, S Lin, SW Krska, SS Stahl
Nature synthesis 2 (10), 998-1008, 2023
122023
A general three-component alkyl petasis boron–mannich reaction
C Hu, J Tsien, SJ Chen, M Kong, RR Merchant, Y Kanda, T Qin
Journal of the American Chemical Society 146 (31), 21769-21777, 2024
82024
Mechanistic insights into radical formation and functionalization in copper/N-fluorobenzenesulfonimide radical-relay reactions
M Mandal, JA Buss, SJ Chen, CJ Cramer, SS Stahl
Chemical Science 15 (4), 1364-1373, 2024
62024
C3 Selective Hydroxylation of Pyridines via Photochemical Valence Isomerization of Pyridine N-Oxides
CY Cai, SJ Chen, RR Merchant, Y Kanda, T Qin
Journal of the American Chemical Society 146 (35), 24257-24264, 2024
32024
Copper-catalyzed benzylic C–H coupling with alcohols via radical relay
H Hu, SJ Chen, S Krska, S Stahl
22019
Accessing 3D molecular diversity via benzylic C–H cross coupling
SJ Chen, CQ He, M Kong, J Wang, S Lin, SW Krska, SS Stahl
12022
TO MARKET, TO MARKET–2021: MACROMOLECULAR THERAPEUTICS
NJ Agard, PS Dragovich, RL Kelly, SA Lim, AM Beal, I Moench, SJ Chen, ...
2022 Medicinal Chemistry Reviews 57, 733-805, 2022
12022
TO MARKET, TO MARKET—2023: MACROMOLECULAR THERAPEUTICS
SA Lim, NJ Agard, RL Kelly, BN Bell, SJ Chen, AM Gram, I Moench, ...
2024 Medicinal Chemistry Review 59, 553-639, 2024
2024
PNU Anthracycline Derivatives and Methods of Use Thereof
WO Patent 2,024,091,894, 2024
2024
Exatecan-Derived ADC Linker-Payloads, Pharmaceutical Compositions, And Uses Thereof
WO Patent 2,024,091,437, 2024
2024
TO MARKET, TO MARKET–2022: MACROMOLECULAR THERAPEUTICS
SA Lim, NJ Agard, RL Kelly, BN Bell, SJ Chen, AM Gram, JR Merritt, ...
2023 Medicinal Chemistry Reviews 58, 713-798, 2023
2023
Copper-catalyzed benzylic C(sp3)–H cross couplings: Methodology development and applications in medicinal chemistry
SJ Chen, H Hu, DL Golden, S Lin, CQ He, SW Krska, SS Stahl
American Chemical Society SciMeetings 3 (2), https://doi.org/10.1021 …, 2022
2022
Copper-Catalyzed Benzylic C–H Cross Couplings: Methodology Development and Applications in Medicinal Chemistry
SJ Chen
University of Wisconsin - Madison, 2021
2021
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