Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization TJ Sargeant, B Lloyd-Lewis, HK Resemann, A Ramos-Montoya, ... Nature cell biology 16 (11), 1057-1068, 2014 | 184 | 2014 |
Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny FM Davis, B Lloyd-Lewis, OB Harris, S Kozar, DJ Winton, L Muresan, ... Nature communications 7 (1), 13053, 2016 | 145 | 2016 |
Mammary stem cells: premise, properties, and perspectives B Lloyd-Lewis, OB Harris, CJ Watson, FM Davis Trends in cell biology 27 (8), 556-567, 2017 | 126 | 2017 |
Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids T Jardé, B Lloyd-Lewis, M Thomas, H Kendrick, L Melchor, L Bougaret, ... Nature communications 7 (1), 13207, 2016 | 119 | 2016 |
Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods B Lloyd-Lewis, FM Davis, OB Harris, JR Hitchcock, FC Lourenco, ... Breast Cancer Research 18, 1-17, 2016 | 108 | 2016 |
Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway REA de Groot, RS Ganji, O Bernatik, B Lloyd-Lewis, K Seipel, K Šedová, ... Science signaling 7 (317), ra26-ra26, 2014 | 108 | 2014 |
DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412 CH Seedhouse, HM Hunter, B Lloyd-Lewis, AM Massip, M Pallis, ... Leukemia 20 (12), 2130-2136, 2006 | 101 | 2006 |
The Stat3 paradox: a killer and an oncogene HK Resemann, CJ Watson, B Lloyd-Lewis Molecular and cellular endocrinology 382 (1), 603-611, 2014 | 83 | 2014 |
Multiscale imaging of basal cell dynamics in the functionally mature mammary gland AJ Stevenson, G Vanwalleghem, TA Stewart, ND Condon, B Lloyd-Lewis, ... Proceedings of the National Academy of Sciences 117 (43), 26822-26832, 2020 | 58 | 2020 |
Notch signalling: sensor and instructor of the microenvironment to coordinate cell fate and organ morphogenesis B Lloyd-Lewis, P Mourikis, S Fre Current opinion in cell biology 61, 16-23, 2019 | 51 | 2019 |
Rip11 is a Rab11-and AS160-RabGAP-binding protein required for insulin-stimulated glucose uptake in adipocytes GI Welsh, SE Leney, B Lloyd-Lewis, M Wherlock, AJ Lindsay, ... Journal of cell science 120 (23), 4197-4208, 2007 | 50 | 2007 |
Neutral lineage tracing of proliferative embryonic and adult mammary stem/progenitor cells B Lloyd-Lewis, FM Davis, OB Harris, JR Hitchcock, CJ Watson Development 145 (14), dev164079, 2018 | 47 | 2018 |
Toward a quantitative understanding of the Wnt/β‐catenin pathway through simulation and experiment B Lloyd‐Lewis, AG Fletcher, TC Dale, HM Byrne Wiley Interdisciplinary Reviews: Systems Biology and Medicine 5 (4), 391-407, 2013 | 45 | 2013 |
Longitudinal high-resolution imaging through a flexible intravital imaging window G Jacquemin, M Benavente-Diaz, S Djaber, A Bore, V Dangles-Marie, ... Science Advances 7 (25), eabg7663, 2021 | 38 | 2021 |
Stat3-mediated alterations in lysosomal membrane protein composition B Lloyd-Lewis, CC Krueger, TJ Sargeant, ME D’Angelo, MJ Deery, ... Journal of Biological Chemistry 293 (12), 4244-4261, 2018 | 31 | 2018 |
Signal transducer and activator of transcription 3 and the phosphatidylinositol 3‐kinase regulatory subunits p55α and p50α regulate autophagy in vivo S Pensa, B Lloyd‐Lewis, TJ Sargeant, HK Resemann, CR Kahn, ... The FEBS journal 281 (20), 4557-4567, 2014 | 23 | 2014 |
Deciphering how early life adiposity influences breast cancer risk using Mendelian randomization M Vabistsevits, G Davey Smith, E Sanderson, TG Richardson, ... Communications Biology 5 (1), 337, 2022 | 22 | 2022 |
Multidimensional imaging of mammary gland development: a window into breast form and function B Lloyd-Lewis Frontiers in Cell and Developmental Biology 8, 203, 2020 | 20 | 2020 |
The immune environment of the mammary gland fluctuates during post-lactational regression and correlates with tumour growth rate J Hitchcock, K Hughes, S Pensa, B Lloyd-Lewis, CJ Watson Development 149 (8), dev200162, 2022 | 12 | 2022 |
In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation B Lloyd-Lewis, F Gobbo, M Perkins, G Jacquemin, M Huyghe, ... Cell reports 38 (10), 2022 | 12 | 2022 |