| Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways M Qian, S Wang, X Guo, J Wang, Z Zhang, W Qiu, X Gao, Z Chen, J Xu, ... Oncogene 39 (2), 428-442, 2020 | 292 | 2020 |
| Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways X Guo, W Qiu, Q Liu, M Qian, S Wang, Z Zhang, X Gao, Z Chen, H Xue, ... Oncogene 37 (31), 4239-4259, 2018 | 265 | 2018 |
| Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR X Guo, H Xue, Q Shao, J Wang, X Guo, X Chen, J Zhang, S Xu, T Li, ... Oncotarget 7 (49), 80521, 2016 | 168 | 2016 |
| Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction J Xu, J Zhang, Z Zhang, Z Gao, Y Qi, W Qiu, Z Pan, Q Guo, B Li, S Zhao, ... Cell Death & Disease 12 (4), 373, 2021 | 158 | 2021 |
| NF1 mutation drives neuronal activity-dependent initiation of optic glioma Y Pan, JD Hysinger, T Barron, NF Schindler, O Cobb, X Guo, B Yalçın, ... Nature 594 (7862), 277-282, 2021 | 155 | 2021 |
| A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155 … H Xue, G Yuan, X Guo, Q Liu, J Zhang, X Gao, X Guo, S Xu, T Li, Q Shao, ... Autophagy 12 (7), 1129-1152, 2016 | 152 | 2016 |
| Glioma exosomes mediate the expansion and function of myeloid‐derived suppressor cells through microRNA‐29a/Hbp1 and microRNA‐92a/Prkar1a pathways X Guo, W Qiu, J Wang, Q Liu, M Qian, S Wang, Z Zhang, X Gao, Z Chen, ... International journal of cancer 144 (12), 3111-3126, 2019 | 141 | 2019 |
| Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth X Guo, Y Pan, M Xiong, S Sanapala, C Anastasaki, O Cobb, S Dahiya, ... Nature communications 11 (1), 2177, 2020 | 130 | 2020 |
| CTLA-4 positive breast cancer cells suppress dendritic cells maturation and function X Chen, Q Shao, S Hao, Z Zhao, Y Wang, X Guo, Y He, W Gao, H Mao Oncotarget 8 (8), 13703, 2017 | 99 | 2017 |
| Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem cell–specific chemokine recruitment of T cells and microglia X Guo, Y Pan, DH Gutmann Neuro-oncology 21 (10), 1250-1262, 2019 | 85 | 2019 |
| Exosomal miR-1246 from glioma patient body fluids drives the differentiation and activation of myeloid-derived suppressor cells W Qiu, X Guo, B Li, J Wang, Y Qi, Z Chen, R Zhao, L Deng, M Qian, ... Molecular Therapy 29 (12), 3449-3464, 2021 | 81 | 2021 |
| Transfer of microRNA via macrophage-derived extracellular vesicles promotes proneural-to-mesenchymal transition in glioma stem cells Z Zhang, J Xu, Z Chen, H Wang, H Xue, C Yang, Q Guo, Y Qi, X Guo, ... Cancer Immunology Research 8 (7), 966-981, 2020 | 74 | 2020 |
| CREBRF is a potent tumor suppressor of glioblastoma by blocking hypoxia-induced autophagy via the CREB3/ATG5 pathway H Xue, J Zhang, X Guo, J Wang, J Li, X Gao, X Guo, T Li, S Xu, P Zhang, ... International journal of oncology 49 (2), 519-528, 2016 | 64 | 2016 |
| Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1) MJ Fisher, DTW Jones, Y Li, X Guo, PS Sonawane, AJ Waanders, ... Acta neuropathologica 141, 605-617, 2021 | 62 | 2021 |
| MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells X Guo, H Xue, X Guo, X Gao, S Xu, S Yan, X Han, T Li, J Shen, G Li Oncotarget 6 (39), 41620, 2015 | 58 | 2015 |
| MicroRNA-29a-3p delivery via exosomes derived from engineered human mesenchymal stem cells exerts tumour suppressive effects by inhibiting migration and vasculogenic mimicry in … Z Zhang, X Guo, X Guo, R Yu, M Qian, S Wang, X Gao, W Qiu, Q Guo, ... Aging (Albany NY) 13 (4), 5055, 2021 | 55 | 2021 |
| Anti‐PD‐L1/TGF‐βR fusion protein (SHR‐1701) overcomes disrupted lymphocyte recovery‐induced resistance to PD‐1/PD‐L1 inhibitors in lung cancer B Cheng, K Ding, P Chen, J Ji, T Luo, X Guo, W Qiu, C Ma, X Meng, ... Cancer Communications 42 (1), 17-36, 2022 | 54 | 2022 |
| Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells X Guo, S Xu, X Gao, J Wang, H Xue, Z Chen, J Zhang, X Guo, M Qian, ... Oncotarget 8 (46), 80358, 2017 | 53 | 2017 |
| Mesenchymal stem cell-derived extracellular vesicles promote microglial M2 polarization after subarachnoid hemorrhage in rats and involve the AMPK/NF-κB signaling pathway M Han, Y Cao, X Guo, X Chu, T Li, H Xue, D Xin, L Yuan, H Ke, G Li, ... Biomedicine & Pharmacotherapy 133, 111048, 2021 | 49 | 2021 |
| Exosomes derived from hypoxic glioma deliver miR-1246 and miR-10b-5p to normoxic glioma cells to promote migration and invasion M Qian, Z Chen, X Guo, S Wang, Z Zhang, W Qiu, Y Qi, S Zhang, J Xu, ... Laboratory Investigation 101 (5), 612-624, 2021 | 46 | 2021 |