Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines A Hollestelle, F Elstrodt, JHA Nagel, WW Kallemeijn, M Schutte Molecular cancer research 5 (2), 195-201, 2007 | 407 | 2007 |
Ultrasensitive in situ visualization of active glucocerebrosidase molecules MD Witte, WW Kallemeijn, J Aten, KY Li, A Strijland, WE Donker-Koopman, ... Nature chemical biology 6 (12), 907-913, 2010 | 300 | 2010 |
Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo WW Kallemeijn, KY Li, MD Witte, ARA Marques, J Aten, S Scheij, J Jiang, ... Angewandte Chemie International Edition 51 (50), 12529-12533, 2012 | 169 | 2012 |
Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies JMFG Aerts, WW Kallemeijn, W Wegdam, M Joao Ferraz, ... Journal of inherited metabolic disease 34, 605-619, 2011 | 169 | 2011 |
LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance M Rothaug, F Zunke, JR Mazzulli, M Schweizer, H Altmeppen, ... Proceedings of the National Academy of Sciences 111 (43), 15573-15578, 2014 | 147 | 2014 |
Gaucher disease and Fabry disease: new markers and insights in pathophysiology for two distinct glycosphingolipidoses MJ Ferraz, WW Kallemeijn, M Mirzaian, DH Moro, A Marques, P Wisse, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 137 | 2014 |
Activity-based probes for functional interrogation of retaining β-glucuronidases L Wu, J Jiang, Y Jin, WW Kallemeijn, CL Kuo, M Artola, W Dai, C Van Elk, ... Nature chemical biology 13 (8), 867-873, 2017 | 119 | 2017 |
On the origin of heterogeneity in (preservation) resistance of Bacillus spores: input for a ‘systems’ analysis approach of bacterial spore outgrowth LM Hornstra, A Ter Beek, JP Smelt, WW Kallemeijn, S Brul International journal of food microbiology 134 (1-2), 9-15, 2009 | 84 | 2009 |
Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models G Kramer, W Wegdam, W Donker‐Koopman, R Ottenhoff, P Gaspar, ... FEBS Open Bio 6 (9), 902-913, 2016 | 81 | 2016 |
In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases J Jiang, WW Kallemeijn, DW Wright, AMCH Van Den Nieuwendijk, ... Chemical science 6 (5), 2782-2789, 2015 | 78 | 2015 |
Detection of active mammalian GH31 α-glucosidases in health and disease using in-class, broad-spectrum activity-based probes J Jiang, CL Kuo, L Wu, C Franke, WW Kallemeijn, BI Florea, E van Meel, ... ACS central science 2 (5), 351-358, 2016 | 74 | 2016 |
In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity‐based protein profiling CL Kuo, WW Kallemeijn, LT Lelieveld, M Mirzaian, I Zoutendijk, A Vardi, ... The FEBS journal 286 (3), 584-600, 2019 | 72 | 2019 |
From covalent glycosidase inhibitors to activity‐based glycosidase probes LI Willems, J Jiang, KY Li, MD Witte, WW Kallemeijn, TJN Beenakker, ... Chemistry–A European Journal 20 (35), 10864-10872, 2014 | 71 | 2014 |
Potent and selective activity-based probes for GH27 human retaining α-galactosidases LI Willems, TJM Beenakker, B Murray, S Scheij, WW Kallemeijn, RG Boot, ... Journal of the American Chemical Society 136 (33), 11622-11625, 2014 | 70 | 2014 |
CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101 M Jak, GGW van Bochove, EA Reits, WW Kallemeijn, JM Tromp, P Umana, ... Blood, The Journal of the American Society of Hematology 118 (19), 5178-5188, 2011 | 66 | 2011 |
Activity‐Based Profiling of Retaining β‐Glucosidases: A Comparative Study MD Witte, MTC Walvoort, KY Li, WW Kallemeijn, WE Donker‐Koopman, ... ChemBioChem 12 (8), 1263-1269, 2011 | 54 | 2011 |
Mechanism-based inhibitors of glycosidases: design and applications WW Kallemeijn, MD Witte, T Wennekes, JMFG Aerts Advances in carbohydrate chemistry and biochemistry 71, 297-338, 2014 | 53 | 2014 |
Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors KY Li, J Jiang, MD Witte, WW Kallemeijn, WE Donker-Koopman, RG Boot, ... Organic & Biomolecular Chemistry 12 (39), 7786-7791, 2014 | 48 | 2014 |
Comparing Cyclophellitol N‐Alkyl and N‐Acyl Cyclophellitol Aziridines as Activity‐Based Glycosidase Probes J Jiang, TJM Beenakker, WW Kallemeijn, GA van der Marel, ... Chemistry–A European Journal 21 (30), 10861-10869, 2015 | 47 | 2015 |
Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins N Alzahofi, T Welz, CL Robinson, EL Page, DA Briggs, AK Stainthorp, ... Nature Communications 11 (1), 3495, 2020 | 46 | 2020 |