Programmed cell death ligand 1 (PD-L1) signaling regulates macrophage proliferation and activation GP Hartley, L Chow, DT Ammons, WH Wheat, SW Dow Cancer immunology research 6 (10), 1260-1273, 2018 | 315 | 2018 |
Mesenchymal stem cells (MSC) derived from induced pluripotent stem cells (iPSC) equivalent to adipose-derived MSC in promoting intestinal healing and microbiome normalization … S Soontararak, L Chow, V Johnson, J Coy, W Wheat, D Regan, S Dow Stem cells translational medicine 7 (6), 456-467, 2018 | 160 | 2018 |
Antibacterial activity of human mesenchymal stem cells mediated directly by constitutively secreted factors and indirectly by activation of innate immune effector cells L Chow, V Johnson, R Impastato, J Coy, A Strumpf, S Dow Stem cells translational medicine 9 (2), 235-249, 2020 | 135 | 2020 |
Mechanisms of immune suppression utilized by canine adipose and bone marrow-derived mesenchymal stem cells L Chow, V Johnson, J Coy, D Regan, S Dow Stem Cells and Development 26 (5), 374-389, 2017 | 86 | 2017 |
PD‐1 expression by canine T cells and functional effects of PD‐1 blockade J Coy, A Caldwell, L Chow, A Guth, S Dow Veterinary and comparative oncology 15 (4), 1487-1502, 2017 | 77 | 2017 |
The angiotensin receptor blocker losartan suppresses growth of pulmonary metastases via AT1R-independent inhibition of CCR2 signaling and monocyte recruitment DP Regan, JW Coy, KK Chahal, L Chow, JN Kurihara, AM Guth, ... The Journal of Immunology 202 (10), 3087-3102, 2019 | 68 | 2019 |
Mesenchymal stem cells recruit CCR2+ monocytes to suppress allergic airway inflammation K Takeda, TL Webb, F Ning, Y Shiraishi, DP Regan, L Chow, MJ Smith, ... The Journal of Immunology 200 (4), 1261-1269, 2018 | 61 | 2018 |
Losartan blocks osteosarcoma-elicited monocyte recruitment, and combined with the kinase inhibitor toceranib, exerts significant clinical benefit in canine metastatic osteosarcoma DP Regan, L Chow, S Das, L Haines, E Palmer, JN Kurihara, JW Coy, ... Clinical Cancer Research 28 (4), 662-676, 2022 | 58 | 2022 |
Safety and immune regulatory properties of canine induced pluripotent stem cell-derived mesenchymal stem cells L Chow, V Johnson, D Regan, W Wheat, S Webb, P Koch, S Dow Stem cell research 25, 221-232, 2017 | 58 | 2017 |
Suppression of canine dendritic cell activation/maturation and inflammatory cytokine release by mesenchymal stem cells occurs through multiple distinct biochemical pathways WH Wheat, L Chow, JN Kurihara, DP Regan, JW Coy, TL Webb, SW Dow Stem Cells and Development 26 (4), 249-262, 2017 | 38 | 2017 |
Amikacin induces rapid dose‐dependent apoptotic cell death in equine chondrocytes and synovial cells in vitro L Pezzanite, L Chow, S Soontararak, J Phillips, L Goodrich, S Dow Equine veterinary journal 52 (5), 715-724, 2020 | 36 | 2020 |
Programmed cell death ligand 1 (PD-L1) signaling regulates macrophage proliferation and activation. Cancer Immunol. Res. 2018; 6: 1260–1273. doi: 10.1158/2326-6066 GP Hartley, L Chow, DT Ammons, WH Wheat, SW Dow CIR-17-0537, 0 | 36 | |
Toll‐like receptor activation of equine mesenchymal stromal cells to enhance antibacterial activity and immunomodulatory cytokine secretion LM Pezzanite, L Chow, V Johnson, GM Griffenhagen, L Goodrich, S Dow Veterinary Surgery 50 (4), 858-871, 2021 | 35 | 2021 |
Humoral immune responses against gut bacteria in dogs with inflammatory bowel disease S Soontararak, L Chow, V Johnson, J Coy, C Webb, S Wennogle, S Dow PLoS One 14 (8), e0220522, 2019 | 30 | 2019 |
Role of innate immunity in initiation and progression of osteoarthritis, with emphasis on horses J Estrada McDermott, L Pezzanite, L Goodrich, K Santangelo, L Chow, ... Animals 11 (11), 3247, 2021 | 25 | 2021 |
Use of in vitro assays to identify antibiotics that are cytotoxic to normal equine chondrocytes and synovial cells L Pezzanite, L Chow, G Piquini, G Griffenhagen, D Ramirez, S Dow, ... Equine veterinary journal 53 (3), 579-589, 2021 | 24 | 2021 |
Local immune and microbiological responses to mucosal administration of a Liposome-TLR agonist immunotherapeutic in dogs W Wheat, L Chow, A Kuzmik, S Soontararak, J Kurihara, M Lappin, S Dow BMC veterinary research 15, 1-13, 2019 | 24 | 2019 |
Activation of upper respiratory tract mucosal innate immune responses in cats by liposomal toll‐like receptor ligand complexes delivered topically W Wheat, L Chow, J Coy, E Contreras, M Lappin, S Dow Journal of veterinary internal medicine 33 (2), 838-845, 2019 | 21 | 2019 |
Reprogramming the canine glioma microenvironment with tumor vaccination plus oral losartan and propranolol induces objective responses DT Ammons, A Guth, AJ Rozental, J Kurihara, AJ Marolf, L Chow, ... Cancer research communications 2 (12), 1657-1667, 2022 | 20 | 2022 |
TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant Staphylococcal septic arthritis in an equine model LM Pezzanite, L Chow, J Phillips, GM Griffenhagen, AR Moore, TP Schaer, ... Annals of translational medicine 10 (21), 2022 | 18 | 2022 |