Interplay between metabolic identities in the intestinal crypt supports stem cell function MJ Rodríguez-Colman, M Schewe, M Meerlo, E Stigter, J Gerrits, ... Nature 543 (7645), 424-427, 2017 | 511 | 2017 |
Integrative multi‐omics analysis of intestinal organoid differentiation RGH Lindeboom, L van Voorthuijsen, KC Oost, MJ Rodríguez‐Colman, ... Molecular systems biology 14 (6), e8227, 2018 | 135 | 2018 |
Mitochondria define intestinal stem cell differentiation downstream of a FOXO/Notch axis MC Ludikhuize, M Meerlo, MP Gallego, D Xanthakis, MB Julià, ... Cell metabolism 32 (5), 889-900. e7, 2020 | 134 | 2020 |
Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism MA Sorolla, MJ Rodríguez-Colman, J Tamarit, Z Ortega, JJ Lucas, I Ferrer, ... Free Radical Biology and Medicine 49 (4), 612-621, 2010 | 123 | 2010 |
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis D Hendriks, JF Brouwers, K Hamer, MH Geurts, L Luciana, S Massalini, ... Nature Biotechnology 41 (11), 1567-1581, 2023 | 92 | 2023 |
Nitric oxide accumulation is required to protect against iron-mediated oxidative stress in frataxin-deficient Arabidopsis plants EJZ Mariana Martin, María José Rodríguez Colman, Diego F Gómez-Casati ... FEBS Letters 583 (3), 542-548, 2009 | 84 | 2009 |
Protein oxidation in Huntington disease MA Sorolla, MJ Rodríguez‐Colman, N Vall‐llaura, J Tamarit, J Ros, ... Biofactors 38 (3), 173-185, 2012 | 59 | 2012 |
FOXO s support the metabolic requirements of normal and tumor cells by promoting IDH 1 expression P Charitou, M Rodriguez‐Colman, J Gerrits, M van Triest, ... EMBO reports 16 (4), 456-466, 2015 | 55 | 2015 |
Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation MA Sorolla, C Nierga, MJ Rodríguez-Colman, G Reverter-Branchat, ... Archives of biochemistry and biophysics 510 (1), 27-34, 2011 | 50 | 2011 |
FOXO transcription factors as mediators of stress adaptation MJ Rodriguez-Colman, TB Dansen, BMT Burgering Nature Reviews Molecular Cell Biology 25 (1), 46-64, 2024 | 47 | 2024 |
Global analysis of protein arginine methylation F Zhang, J Kerbl-Knapp, MJR Colman, A Meinitzer, T Macher, N Vujić, ... Cell reports methods 1 (2), 2021 | 47 | 2021 |
Metabolic regulation of stem cells and differentiation: a forkhead box O transcription factor perspective MC Ludikhuize, MJ Rodríguez Colman Antioxidants & redox signaling 34 (13), 1004-1024, 2021 | 44 | 2021 |
Protocol to profile the bioenergetics of organoids using Seahorse MC Ludikhuize, M Meerlo, BMT Burgering, MJR Colman STAR protocols 2 (1), 100386, 2021 | 43 | 2021 |
The forkhead transcription factor Hcm1 promotes mitochondrial biogenesis and stress resistance in yeast MJ Rodriguez-Colman, G Reverter-Branchat, MA Sorolla, J Tamarit, J Ros, ... Journal of Biological Chemistry 285 (47), 37092-37101, 2010 | 38 | 2010 |
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene KC Oost, L van Voorthuijsen, A Fumagalli, RGH Lindeboom, J Sprangers, ... Cell reports 22 (6), 1600-1614, 2018 | 35 | 2018 |
The FOX transcription factor Hcm1 regulates oxidative metabolism in response to early nutrient limitation in yeast. Role of Snf1 and Tor1/Sch9 kinases MJ Rodríguez-Colman, MA Sorolla, N Vall-Llaura, J Tamarit, J Ros, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (8), 2004-2015, 2013 | 31 | 2013 |
Reversible glutathionylation of Sir2 by monothiol glutaredoxins Grx3/4 regulates stress resistance N Vall-Llaura, G Reverter-Branchat, C Vived, N Weertman, ... Free Radical Biology and Medicine 96, 45-56, 2016 | 21 | 2016 |
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells M Hornsveld, FM Feringa, L Krenning, J van den Berg, LMM Smits, ... Cell Reports 34 (4), 2021 | 17 | 2021 |
Rewiring glucose metabolism improves 5-FU efficacy in p53-deficient/KRASG12D glycolytic colorectal tumors MC Ludikhuize, S Gevers, NTB Nguyen, M Meerlo, SKS Roudbari, ... Communications biology 5 (1), 1159, 2022 | 13 | 2022 |
Impaired PLP-dependent metabolism in brain samples from Huntington disease patients and transgenic R6/1 mice MA Sorolla, MJ Rodríguez-Colman, N Vall-Llaura, C Vived, ... Metabolic brain disease 31, 579-586, 2016 | 7 | 2016 |