| ER-associated degradation: Protein quality control and beyond A Ruggiano, O Foresti, P Carvalho Journal of Cell Biology 204 (6), 869-879, 2014 | 725 | 2014 |
| Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4 O Foresti, A Ruggiano, HK Hannibal-Bach, CS Ejsing, P Carvalho Elife 2, e00953, 2013 | 224 | 2013 |
| Key steps in ERAD of luminal ER proteins reconstituted with purified components A Stein, A Ruggiano, P Carvalho, TA Rapoport Cell 158 (6), 1375-1388, 2014 | 214 | 2014 |
| A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum E Fasana, M Fossati, A Ruggiano, S Brambillasca, CC Hoogenraad, ... The faseb journal 24 (5), 1419-1430, 2010 | 128 | 2010 |
| TEX264 coordinates p97-and SPRTN-mediated resolution of topoisomerase 1-DNA adducts J Fielden, K Wiseman, I Torrecilla, S Li, S Hume, SC Chiang, A Ruggiano, ... Nature communications 11 (1), 1274, 2020 | 99 | 2020 |
| Spatial control of lipid droplet proteins by the ERAD ubiquitin ligase Doa10 A Ruggiano, G Mora, L Buxó, P Carvalho The EMBO journal 35 (15), 1644-1655, 2016 | 88 | 2016 |
| DNA–protein crosslink proteases in genome stability A Ruggiano, K Ramadan Communications Biology 4 (1), 11, 2021 | 83 | 2021 |
| DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans J Fielden, A Ruggiano, M Popović, K Ramadan DNA repair 71, 198-204, 2018 | 81 | 2018 |
| Restructured endoplasmic reticulum generated by mutant amyotrophic lateral sclerosis-linked VAPB is cleared by the proteasome G Papiani, A Ruggiano, M Fossati, A Raimondi, G Bertoni, M Francolini, ... Journal of cell science 125 (15), 3601-3611, 2012 | 60 | 2012 |
| The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability A Ruggiano, B Vaz, S Kilgas, M Popović, G Rodriguez-Berriguete, ... Cell Reports 37 (10), 2021 | 42 | 2021 |
| Metformin decelerates aging clock in male monkeys Y Yang, X Lu, N Liu, S Ma, H Zhang, Z Zhang, K Yang, M Jiang, Z Zheng, ... Cell 187 (22), 6358-6378. e29, 2024 | 29 | 2024 |
| Amyotrophic lateral sclerosis-linked mutant VAPB inclusions do not interfere with protein degradation pathways or intracellular transport in a cultured cell model P Genevini, G Papiani, A Ruggiano, L Cantoni, F Navone, N Borgese PloS one 9 (11), e113416, 2014 | 29 | 2014 |
| The trinity of SPRTN protease regulation A Ruggiano, K Ramadan Trends in Biochemical Sciences 46 (1), 2-4, 2021 | 12 | 2021 |
| TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival P Lascaux, G Hoslett, S Tribble, C Trugenberger, I Antičević, C Otten, ... Cell 187 (20), 5698-5718. e26, 2024 | 11 | 2024 |
| Isolation and detection of DNA–protein crosslinks in mammalian cells I Torrecilla, A Ruggiano, K Kiianitsa, F Aljarbou, P Lascaux, G Hoslett, ... Nucleic Acids Research 52 (2), 525-547, 2024 | 7 | 2024 |
| SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability B Vaz, A Ruggiano, M Popovic, G Rodriguez-Berriguete, S Kilgas, ... bioRxiv, 2020.02. 14.949289, 2020 | 5 | 2020 |
| The dual ubiquitin binding mode of SPRTN secures rapid spatiotemporal proteolysis of DNA-protein crosslinks W Song, Y Zhao, A Ruggiano, C Redfield, joseph Newman, X Zhu, ... bioRxiv, 2024.11. 26.625361, 2024 | | 2024 |
| Control of endoplasmatic reticulum homeostasis by Doa10-dependent protein degradation A Ruggiano Universitat Pompeu Fabra, 2015 | | 2015 |
| Reinforcement of organelle identity by the ERAD ubiquitin ligase Doa10. A Ruggiano, P Carvalho MOLECULAR BIOLOGY OF THE CELL 25, 2014 | | 2014 |
| Amyotrophic Lateral Sclerosis-Linked Mutant VAPB Inclusions Do Not Interfere with P Genevini, G Papiani, A Ruggiano, L Cantoni, F Navone | | 2014 |
