| Sobol sensitivity analysis: a tool to guide the development and evaluation of systems pharmacology models XY Zhang, MN Trame, LJ Lesko, S Schmidt CPT: pharmacometrics & systems pharmacology 4 (2), 69-79, 2015 | 530 | 2015 |
| Significance of protein binding in pharmacokinetics and pharmacodynamics S Schmidt, D Gonzalez, H Derendorf Journal of pharmaceutical sciences 99 (3), 1107-1122, 2010 | 392 | 2010 |
| Clinical pharmacokinetics and pharmacodynamics of clopidogrel XL Jiang, S Samant, LJ Lesko, S Schmidt Clinical pharmacokinetics 54 (2), 147-166, 2015 | 230 | 2015 |
| Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents D Gonzalez, S Schmidt, H Derendorf Clinical microbiology reviews 26 (2), 274-288, 2013 | 178 | 2013 |
| Reduced subcutaneous tissue distribution of cefazolin in morbidly obese versus non-obese patients determined using clinical microdialysis MJE Brill, API Houwink, S Schmidt, EPA Van Dongen, EJ Hazebroek, ... Journal of Antimicrobial Chemotherapy 69 (3), 715-723, 2014 | 155 | 2014 |
| Individualization of drug therapy: history, present state, and opportunities for the future LJ Lesko, S Schmidt Clinical pharmacology & Therapeutics 92 (4), 458-466, 2012 | 138 | 2012 |
| Effect of protein binding on the pharmacological activity of highly bound antibiotics S Schmidt, K Röck, M Sahre, O Burkhardt, M Brunner, MT Lobmeyer, ... Antimicrobial agents and chemotherapy 52 (11), 3994-4000, 2008 | 135 | 2008 |
| Application of physiologically based pharmacokinetic modeling to predict acetaminophen metabolism and pharmacokinetics in children XL Jiang, P Zhao, JS Barrett, LJ Lesko, S Schmidt CPT: pharmacometrics & systems pharmacology 2 (10), 1-9, 2013 | 124 | 2013 |
| PK/PD: new insights for antibacterial and antiviral applications S Schmidt, A Barbour, M Sahre, KH Rand, H Derendorf Current opinion in pharmacology 8 (5), 549-556, 2008 | 111 | 2008 |
| Soft tissue penetration of cefuroxime determined by clinical microdialysis in morbidly obese patients undergoing abdominal surgery A Barbour, S Schmidt, WR Rout, K Ben-David, O Burkhardt, H Derendorf International journal of antimicrobial agents 34 (3), 231-235, 2009 | 105 | 2009 |
| Spectral element filtering techniques for large eddy simulation with dynamic estimation HM Blackburn, S Schmidt Journal of Computational Physics 186 (2), 610-629, 2003 | 102 | 2003 |
| Open systems pharmacology community—an open access, open source, open science approach to modeling and simulation in pharmaceutical sciences J Lippert, R Burghaus, A Edginton, S Frechen, M Karlsson, A Kovar, ... CPT: pharmacometrics & systems pharmacology 8 (12), 878, 2019 | 95 | 2019 |
| When is protein binding important? J Heuberger, S Schmidt, H Derendorf Journal of pharmaceutical sciences 102 (9), 3458-3467, 2013 | 94 | 2013 |
| Clinical microdialysis in skin and soft tissues: an update S Schmidt, R Banks, V Kumar, KH Rand, H Derendorf The Journal of Clinical Pharmacology 48 (3), 351-364, 2008 | 93 | 2008 |
| Ontogeny of hepatic transporters and drug-metabolizing enzymes in humans and in nonclinical species BD Van Groen, J Nicolaï, AC Kuik, S Van Cruchten, E Van Peer, A Smits, ... Pharmacological Reviews 73 (2), 597-678, 2021 | 84 | 2021 |
| Clinical pharmacokinetics and pharmacodynamics of tigecycline A Barbour, S Schmidt, B Ma, L Schiefelbein, KH Rand, O Burkhardt, ... Clinical pharmacokinetics 48, 575-584, 2009 | 84 | 2009 |
| Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis O Burkhardt, M Brunner, S Schmidt, M Grant, Y Tang, H Derendorf Journal of antimicrobial chemotherapy 58 (3), 632-636, 2006 | 73 | 2006 |
| Machine learning in drug discovery and development part 1: a primer A Talevi, JF Morales, G Hather, JT Podichetty, S Kim, PC Bloomingdale, ... CPT: pharmacometrics & systems pharmacology 9 (3), 129-142, 2020 | 72 | 2020 |
| Rowland and Tozer's clinical pharmacokinetics and pharmacodynamics: concepts and applications H Derendorf, S Schmidt Lippincott Williams & Wilkins, 2019 | 69 | 2019 |
| Integrated population pharmacokinetic analysis of rivaroxaban across multiple patient populations S Willmann, L Zhang, M Frede, D Kubitza, W Mueck, S Schmidt, A Solms, ... CPT: Pharmacometrics & Systems Pharmacology 7 (5), 309-320, 2018 | 68 | 2018 |
Mirjam N Trame, Pharm D, PhDAssistant Professor, University of FloridaVerified email at cop.ufl.edu
