Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF GC O'Keeffe, P Tyers, D Aarsland, JW Dalley, RA Barker, MA Caldwell Proceedings of the National Academy of Sciences 106 (21), 8754-8759, 2009 | 244 | 2009 |
Multiplex Immunoassay for Serological Diagnosis of Mycobacterium bovis Infection in Cattle C Whelan, E Shuralev, G O'Keeffe, P Hyland, HF Kwok, P Snoddy, ... Clinical and Vaccine Immunology 15 (12), 1834-1838, 2008 | 132 | 2008 |
Dopaminergic modulation of neurogenesis in the subventricular zone of the adult brain GC O’Keeffe, RA Barker, MA Caldwell Cell Cycle 8 (18), 2888-2894, 2009 | 124 | 2009 |
Resistance is not futile: gliotoxin biosynthesis, functionality and utility SK Dolan, G O’Keeffe, GW Jones, S Doyle Trends in microbiology 23 (7), 419-428, 2015 | 123 | 2015 |
Genomic and Proteomic Dissection of the Ubiquitous Plant Pathogen, Armillaria mellea: Toward a New Infection Model System C Collins, TM Keane, DJ Turner, G O’Keeffe, DA Fitzpatrick, S Doyle Journal of proteome research 12 (6), 2552-2570, 2013 | 107 | 2013 |
Regulation of nonribosomal peptide synthesis: bis-thiomethylation attenuates gliotoxin biosynthesis in Aspergillus fumigatus SK Dolan, RA Owens, G O’Keeffe, S Hammel, DA Fitzpatrick, GW Jones, ... Chemistry & biology 21 (8), 999-1012, 2014 | 90 | 2014 |
The catechol-O-methyltransferase Val158Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson’s disease: a PET study K Wu, D O’Keeffe, M Politis, GC O’Keeffe, TW Robbins, SK Bose, ... Brain 135 (8), 2449-2457, 2012 | 87 | 2012 |
Gliotoxin effects on fungal growth: mechanisms and exploitation S Carberry, E Molloy, S Hammel, G O’Keeffe, GW Jones, K Kavanagh, ... Fungal Genetics and Biology 49 (4), 302-312, 2012 | 75 | 2012 |
The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis L Gallagher, RA Owens, SK Dolan, G O'Keeffe, M Schrettl, K Kavanagh, ... Eukaryotic Cell 11 (10), 1226-1238, 2012 | 67 | 2012 |
Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus KJ Sheridan, BE Lechner, GO Keeffe, MA Keller, ER Werner, H Lindner, ... Scientific Reports 6 (1), 35306, 2016 | 65 | 2016 |
Interplay between gliotoxin resistance, secretion, and the methyl/methionine cycle in Aspergillus fumigatus RA Owens, G O'Keeffe, EB Smith, SK Dolan, S Hammel, KJ Sheridan, ... Eukaryotic cell 14 (9), 941-957, 2015 | 56 | 2015 |
RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus G O’Keeffe, S Hammel, RA Owens, TM Keane, DA Fitzpatrick, GW Jones, ... BMC genomics 15, 1-26, 2014 | 56 | 2014 |
Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus KA O'Hanlon, T Cairns, D Stack, M Schrettl, EM Bignell, K Kavanagh, ... Infection and immunity 79 (10), 3978-3992, 2011 | 47 | 2011 |
Exploration of sulfur assimilation of Aspergillus fumigatus reveals biosynthesis of sulfur-containing amino acids as a virulence determinant J Amich, M Dümig, G O'Keeffe, J Binder, S Doyle, A Beilhack, ... Infection and immunity 84 (4), 917-929, 2016 | 44 | 2016 |
Biomarkers in Huntington's and Parkinson's Disease GC O’Keeffe, AW Michell, RA Barker Annals of the New York Academy of Sciences 1180 (1), 97-110, 2009 | 40 | 2009 |
Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease ML Choi, F Begeti, JH Oh, SY Lee, GC O'Keeffe, CD Clelland, P Tyers, ... Neurobiology of disease 66, 19-27, 2014 | 18 | 2014 |
Proteomic Characterization of Armillaria mellea Reveals Oxidative Stress Response Mechanisms and Altered Secondary Metabolism Profiles C Collins, R Hurley, N Almutlaqah, G O’Keeffe, TM Keane, DA Fitzpatrick, ... Microorganisms 5 (3), 60, 2017 | 17 | 2017 |
Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bγ deletion in Aspergillus fumigatus G O'Keeffe, C Jöchl, K Kavanagh, S Doyle Protein Science 22 (11), 1612-1622, 2013 | 15 | 2013 |
Dopamine stimulates epidermal growth factor release from adult neural precursor cells derived from the subventricular zone by a disintegrin and metalloprotease GC O’Keeffe, RA Barker Neuroreport 22 (18), 956-958, 2011 | 11 | 2011 |
Virulence characteristics of Aspergillus fumigatus RA Owens, G O’Keeffe, KA O'Hanlon, L Gallagher, S Doyle Human pathogenic fungi: molecular biology and pathogenic mechanisms, 163-194, 2014 | 4 | 2014 |