Genomic correlates of clinical outcome in advanced prostate cancer W Abida, J Cyrta, G Heller, D Prandi, J Armenia, I Coleman, M Cieslik, ... Proceedings of the National Academy of Sciences 116 (23), 11428-11436, 2019 | 1200 | 2019 |
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant S Sun, CCT Sprenger, RL Vessella, K Haugk, K Soriano, EA Mostaghel, ... The Journal of clinical investigation 120 (8), 2715-2730, 2010 | 899 | 2010 |
Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B Y Sun, J Campisi, C Higano, TM Beer, P Porter, I Coleman, L True, ... Nature medicine 18 (9), 1359-1368, 2012 | 889 | 2012 |
The long tail of oncogenic drivers in prostate cancer J Armenia, SAM Wankowicz, D Liu, J Gao, R Kundra, E Reznik, ... Nature genetics 50 (5), 645-651, 2018 | 829 | 2018 |
Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer A Kumar, I Coleman, C Morrissey, X Zhang, LD True, R Gulati, R Etzioni, ... Nature medicine 22 (4), 369-378, 2016 | 750 | 2016 |
Androgen receptor pathway-independent prostate cancer is sustained through FGF signaling EG Bluemn, IM Coleman, JM Lucas, RT Coleman, S Hernandez-Lopez, ... Cancer cell 32 (4), 474-489. e6, 2017 | 688 | 2017 |
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer EA Mostaghel, ST Page, DW Lin, L Fazli, IM Coleman, LD True, ... Cancer research 67 (10), 5033-5041, 2007 | 644 | 2007 |
The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms C Bavik, I Coleman, JP Dean, B Knudsen, S Plymate, PS Nelson Cancer research 66 (2), 794-802, 2006 | 561 | 2006 |
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis JM Lucas, C Heinlein, T Kim, SA Hernandez, MS Malik, LD True, ... Cancer discovery 4 (11), 1310-1325, 2014 | 538 | 2014 |
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1 C Cai, HH He, S Chen, I Coleman, H Wang, Z Fang, S Chen, PS Nelson, ... Cancer cell 20 (4), 457-471, 2011 | 521 | 2011 |
A causal role for ERG in neoplastic transformation of prostate epithelium O Klezovitch, M Risk, I Coleman, JM Lucas, M Null, LD True, PS Nelson, ... Proceedings of the National Academy of Sciences 105 (6), 2105-2110, 2008 | 392 | 2008 |
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer A Sharp, I Coleman, W Yuan, C Sprenger, D Dolling, DN Rodrigues, ... The Journal of clinical investigation 129 (1), 192-208, 2019 | 385 | 2019 |
The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression A Sharma, WS Yeow, A Ertel, I Coleman, N Clegg, C Thangavel, ... The Journal of clinical investigation 120 (12), 4478-4492, 2010 | 365 | 2010 |
Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer MP Labrecque, IM Coleman, LG Brown, LD True, L Kollath, B Lakely, ... The Journal of clinical investigation 129 (10), 4492-4505, 2019 | 357 | 2019 |
A molecular correlate to the Gleason grading system for prostate adenocarcinoma L True, I Coleman, S Hawley, CY Huang, D Gifford, R Coleman, TM Beer, ... Proceedings of the National Academy of Sciences 103 (29), 10991-10996, 2006 | 346 | 2006 |
Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate LE Pascal, LD True, DS Campbell, EW Deutsch, M Risk, IM Coleman, ... BMC genomics 9, 1-13, 2008 | 326 | 2008 |
Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers A Kumar, TA White, AP MacKenzie, N Clegg, C Lee, RF Dumpit, ... Proceedings of the National Academy of Sciences 108 (41), 17087-17092, 2011 | 311 | 2011 |
LuCaP prostate cancer patient‐derived xenografts reflect the molecular heterogeneity of advanced disease and serve as models for evaluating cancer therapeutics HM Nguyen, RL Vessella, C Morrissey, LG Brown, IM Coleman, ... The Prostate 77 (6), 654-671, 2017 | 299 | 2017 |
Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer CC Pritchard, C Morrissey, A Kumar, X Zhang, C Smith, I Coleman, ... Nature communications 5 (1), 4988, 2014 | 297 | 2014 |
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy P Carlson, A Dasgupta, CA Grzelak, J Kim, A Barrett, IM Coleman, ... Nature cell biology 21 (2), 238-250, 2019 | 254 | 2019 |