Cytochrome P450s in the synthesis of cholesterol and bile acids–from mouse models to human diseases G Lorbek, M Lewinska, D Rozman The FEBS journal 279 (9), 1516-1533, 2012 | 236 | 2012 |
Metabolic rearrangements in primary liver cancers: cause and consequences L Satriano, M Lewinska, PM Rodrigues, JM Banales, JB Andersen Nature reviews Gastroenterology & hepatology 16 (12), 748-766, 2019 | 202 | 2019 |
Lipid alterations in chronic liver disease and liver cancer B Paul, M Lewinska, JB Andersen JHEP reports 4 (6), 100479, 2022 | 194 | 2022 |
Desmoplastic tumor microenvironment and immunotherapy in cholangiocarcinoma D Høgdall, M Lewinska, JB Andersen Trends in cancer 4 (3), 239-255, 2018 | 122 | 2018 |
Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma C Raggi, ML Taddei, E Sacco, N Navari, M Correnti, B Piombanti, ... Journal of hepatology 74 (6), 1373-1385, 2021 | 105 | 2021 |
The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma M Lewinska, A Santos-Laso, E Arretxe, C Alonso, E Zhuravleva, ... EBioMedicine 73, 2021 | 58 | 2021 |
Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury G Lorbek, M Perše, J Jeruc, P Juvan, FM Gutierrez-Mariscal, M Lewinska, ... Scientific reports 5 (1), 8777, 2015 | 49 | 2015 |
The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells G Di Maira, A Gentilini, M Pastore, A Caligiuri, B Piombanti, C Raggi, ... Oncogenesis 8 (11), 61, 2019 | 35 | 2019 |
Polymorphisms of CYP51A1 from Cholesterol Synthesis: Associations with Birth Weight and Maternal Lipid Levels and Impact on CYP51 Protein Structure M Lewińska, U Zelenko, F Merzel, S Golic Grdadolnik, JC Murray, ... PloS one 8 (12), e82554, 2013 | 35 | 2013 |
PRR14 is a novel activator of the PI3K pathway promoting lung carcinogenesis M Yang, M Lewinska, X Fan, J Zhu, ZM Yuan Oncogene 35 (42), 5527-5538, 2016 | 25 | 2016 |
The protease‐inhibitor SerpinB3 as a critical modulator of the stem‐like subset in human cholangiocarcinoma M Correnti, A Cappon, M Pastore, B Piombanti, G Lori, DVPN Oliveira, ... Liver International 42 (1), 233-248, 2022 | 24 | 2022 |
miR‐21‐5p promotes NASH‐related hepatocarcinogenesis PM Rodrigues, MB Afonso, AL Simão, T Islam, MM Gaspar, CJ O'Rourke, ... Liver International 43 (10), 2256-2274, 2023 | 21 | 2023 |
ZBTB7A governs estrogen receptor alpha expression in breast cancer ME Molloy, M Lewinska, AK Williamson, TT Nguyen, G Kuser-Abali, ... Journal of molecular cell biology 10 (4), 273-284, 2018 | 19 | 2018 |
MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells L Duwe, P Munoz-Garrido, M Lewinska, J Lafuente-Barquero, L Satriano, ... Journal of hepatology 78 (2), 364-375, 2023 | 17 | 2023 |
Hidden disease susceptibility and sexual dimorphism in the heterozygous knockout of Cyp51 from cholesterol synthesis M Lewinska, P Juvan, M Perse, J Jeruc, S Kos, G Lorbek, Z Urlep, ... PLoS One 9 (11), e112787, 2014 | 15 | 2014 |
Semaglutide reduces tumor burden in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH-HCC with advanced fibrosis HH Hansen, S Pors, MW Andersen, M Vyberg, J Nøhr-Meldgaard, ... Scientific Reports 13 (1), 23056, 2023 | 11 | 2023 |
Low nucleotide variability of CYP51A1 in humans: meta-analysis of cholesterol and bile acid synthesis and xenobiotic metabolism pathways. M Lewiñska, UP Zmrzljak, D Rozman Acta Chimica Slovenica 60 (4), 2013 | 9 | 2013 |
Serum lipidome unravels a diagnostic potential in bile acid diarrhoea M Lewinska, ML Kårhus, AMG Ellegaard, M Romero-Gómez, RIR Macias, ... Gut 72 (9), 1698-1708, 2023 | 8 | 2023 |
Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma M Lewinska, E Zhuravleva, L Satriano, MB Martinez, DK Bhatt, ... Gastroenterology 166 (5), 886-901. e7, 2024 | 6 | 2024 |
Therapeutic rationale to target highly expressed aurora kinase A conferring poor prognosis in cholangiocarcinoma X Ding, T Huang, C Peng, KS Ahn, JB Andersen, M Lewinska, Y Cao, ... Journal of Cancer 11 (8), 2241, 2020 | 4 | 2020 |