| Analysis of circulating tumor DNA to monitor metastatic breast cancer SJ Dawson, DWY Tsui, M Murtaza, H Biggs, OM Rueda, SF Chin, ... New England Journal of Medicine 368 (13), 1199-1209, 2013 | 2607 | 2013 |
| Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA M Murtaza, SJ Dawson, DWY Tsui, D Gale, T Forshew, AM Piskorz, ... Nature 497 (7447), 108-112, 2013 | 1973 | 2013 |
| Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA T Forshew, M Murtaza, C Parkinson, D Gale, DWY Tsui, F Kaper, ... Science translational medicine 4 (136), 136ra68-136ra68, 2012 | 1606 | 2012 |
| Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer T Cooks, IS Pateras, O Tarcic, H Solomon, AJ Schetter, S Wilder, ... Cancer cell 23 (5), 634-646, 2013 | 539 | 2013 |
| Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 T Cooks, IS Pateras, LM Jenkins, KM Patel, AI Robles, J Morris, ... Nature communications 9 (1), 771, 2018 | 476 | 2018 |
| Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis JMJ Weaver, CS Ross-Innes, N Shannon, AG Lynch, T Forshew, ... Nature genetics 46 (8), 837-843, 2014 | 399 | 2014 |
| Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome P Gissen, CA Johnson, NV Morgan, JM Stapelbroek, T Forshew, ... Nature genetics 36 (4), 400-404, 2004 | 373 | 2004 |
| Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas T Forshew, RG Tatevossian, ARJ Lawson, J Ma, G Neale, ... The Journal of pathology 218 (2), 172-181, 2009 | 321 | 2009 |
| Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells M Vinci, A Burford, V Molinari, K Kessler, S Popov, M Clarke, KR Taylor, ... Nature medicine 24 (8), 1204-1215, 2018 | 187 | 2018 |
| Targeted Therapy for BRAFV600E Malignant Astrocytoma TP Nicolaides, H Li, DA Solomon, S Hariono, R Hashizume, K Barkovich, ... Clinical Cancer Research 17 (24), 7595-7604, 2011 | 177 | 2011 |
| Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA D Gale, ARJ Lawson, K Howarth, M Madi, B Durham, S Smalley, ... PloS one 13 (3), e0194630, 2018 | 167 | 2018 |
| Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma L Gossage, M Murtaza, AF Slatter, CP Lichtenstein, A Warren, B Haynes, ... Genes, chromosomes and cancer 53 (1), 38-51, 2014 | 161 | 2014 |
| Mapping of a novel locus for achromatopsia (ACHM4) to 1p and identification of a germline mutation in the α subunit of cone transducin (GNAT2) IA Aligianis, T Forshew, S Johnson, M Michaelides, CA Johnson, ... Journal of medical genetics 39 (9), 656, 2002 | 146 | 2002 |
| Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC) B Ricciuti, G Jones, M Severgnini, JV Alessi, G Recondo, M Lawrence, ... Journal for immunotherapy of cancer 9 (3), 2021 | 133 | 2021 |
| Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling V Plagnol, S Woodhouse, K Howarth, S Lensing, M Smith, M Epstein, ... PloS one 13 (3), e0193802, 2018 | 116 | 2018 |
| MAPK pathway activation and the origins of pediatric low‐grade astrocytomas RG Tatevossian, ARJ Lawson, T Forshew, GFL Hindley, DW Ellison, ... Journal of cellular physiology 222 (3), 509-514, 2010 | 115 | 2010 |
| Association of plasma and urinary mutant DNA with clinical outcomes in muscle invasive bladder cancer KM Patel, KE Van Der Vos, CG Smith, F Mouliere, D Tsui, J Morris, ... Scientific Reports 7 (1), 5554, 2017 | 110 | 2017 |
| MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma S Haston, S Pozzi, G Carreno, S Manshaei, L Panousopoulos, ... Development 144 (12), 2141-2152, 2017 | 98 | 2017 |
| MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas RG Tatevossian, B Tang, J Dalton, T Forshew, AR Lawson, J Ma, G Neale, ... Acta neuropathologica 120, 731-743, 2010 | 96 | 2010 |
| Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours TJ Stone, A Keeley, A Virasami, W Harkness, M Tisdall, ... Acta neuropathologica 135, 115-129, 2018 | 87 | 2018 |
Nitzan RosenfeldCancer Research UK Cambridge Institute and University of CambridgeVerified email at cruk.cam.ac.uk