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Samuel McBrayer
Samuel McBrayer
Assistant Professor of Pediatrics, UT Southwestern Medical Center
Verified email at utsouthwestern.edu
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Cited by
Cited by
Year
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ...
Science 363 (6432), 1217-1222, 2019
3882019
Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma
SK McBrayer, JR Mayers, GJ DiNatale, DD Shi, J Khanal, AA Chakraborty, ...
Cell 175 (1), 101-116. e25, 2018
3402018
Developmental regulation of mitochondrial apoptosis by c-Myc governs age-and tissue-specific sensitivity to cancer therapeutics
KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer, ...
Cancer cell 31 (1), 142-156, 2017
2562017
Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy
SK McBrayer, JC Cheng, S Singhal, NL Krett, ST Rosen, M Shanmugam
Blood, The Journal of the American Society of Hematology 119 (20), 4686-4697, 2012
2272012
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ...
Nature communications 12 (1), 4860, 2021
1902021
Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function
G Notarangelo, JB Spinelli, EM Perez, GJ Baker, K Kurmi, I Elia, ...
Science 377 (6614), 1519-1529, 2022
1852022
Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
MG Oser, R Fonseca, AA Chakraborty, R Brough, A Spektor, RB Jennings, ...
Cancer discovery 9 (2), 230-247, 2019
1572019
Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion
IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ...
Cell metabolism 29 (5), 1166-1181. e6, 2019
1462019
Isocitrate dehydrogenase (IDH) mutant gliomas: a Society for Neuro-Oncology (SNO) consensus review on diagnosis, management, and future directions
JJ Miller, LN Gonzalez Castro, S McBrayer, M Weller, T Cloughesy, ...
Neuro-oncology 25 (1), 4-25, 2023
1322023
Oncogenic R132 IDH1 mutations limit NADPH for de novo lipogenesis through (D) 2-hydroxyglutarate production in fibrosarcoma cells
MG Badur, T Muthusamy, SJ Parker, S Ma, SK McBrayer, T Cordes, ...
Cell reports 25 (4), 1018-1026. e4, 2018
972018
Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma
R Bajpai, A Sharma, A Achreja, CL Edgar, C Wei, AA Siddiqa, VA Gupta, ...
Nature communications 11 (1), 1228, 2020
872020
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ...
Cancer cell 40 (9), 939-956. e16, 2022
812022
Molecular and metabolic mechanisms underlying selective 5-aminolevulinic acid-induced fluorescence in gliomas
JI Traylor, MN Pernik, AC Sternisha, SK McBrayer, KG Abdullah
Cancers 13 (3), 580, 2021
692021
Targeting the Warburg effect in hematological malignancies: from PET to therapy
M Shanmugam, SK McBrayer, ST Rosen
Current opinion in oncology 21 (6), 531-536, 2009
652009
Establishment of patient-derived organoid models of lower-grade glioma
KG Abdullah, CE Bird, JD Buehler, LC Gattie, MR Savani, AC Sternisha, ...
Neuro-oncology 24 (4), 612-623, 2022
632022
Peptidic degron for IMiD-induced degradation of heterologous proteins
V Koduri, SK McBrayer, E Liberzon, AC Wang, KJ Briggs, H Cho, ...
Proceedings of the National Academy of Sciences 116 (7), 2539-2544, 2019
572019
Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine
M Shanmugam, SK McBrayer, J Qian, K Raikoff, MJ Avram, S Singhal, ...
Journal of Biological Chemistry 284 (39), 26816-26830, 2009
562009
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
S Pal, JP Kaplan, H Nguyen, SA Stopka, MR Savani, MS Regan, ...
Cancer Cell 40 (9), 957-972. e10, 2022
552022
Contemporary mouse models in glioma research
WH Hicks, CE Bird, JI Traylor, DD Shi, TY El Ahmadieh, TE Richardson, ...
Cells 10 (3), 712, 2021
462021
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase
AA Chakraborty, E Nakamura, J Qi, A Creech, JD Jaffe, J Paulk, JS Novak, ...
Science translational medicine 9 (398), eaal5272, 2017
402017
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