| Targeting CD40-induced TRAF6 signaling in macrophages reduces atherosclerosis TTP Seijkens, CM van Tiel, PJH Kusters, D Atzler, O Soehnlein, ... Journal of the American College of Cardiology 71 (5), 527-542, 2018 | 175 | 2018 |
| Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, ... Proceedings of the National Academy of Sciences 111 (7), 2686-2691, 2014 | 147 | 2014 |
| Comparative analysis of pharmacophore screening tools MPA Sanders, AJM Barbosa, B Zarzycka, GAF Nicolaes, JPG Klomp, ... Journal of chemical information and modeling 52 (6), 1607-1620, 2012 | 116 | 2012 |
| Harnessing ion-binding sites for GPCR pharmacology B Zarzycka, SA Zaidi, BL Roth, V Katritch, EL Barker Pharmacological reviews 71 (4), 571-595, 2019 | 100 | 2019 |
| Discovery of small molecule CD40–TRAF6 inhibitors B Zarzycka, T Seijkens, SB Nabuurs, T Ritschel, J Grommes, O Soehnlein, ... Journal of chemical information and modeling 55 (2), 294-307, 2015 | 77 | 2015 |
| iPPI-DB: an online database of modulators of protein–protein interactions CM Labbé, MA Kuenemann, B Zarzycka, G Vriend, GAF Nicolaes, ... Nucleic acids research 44 (D1), D542-D547, 2016 | 66 | 2016 |
| Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice SM van den Berg, TTP Seijkens, PJH Kusters, B Zarzycka, L Beckers, ... International journal of obesity 39 (5), 782-790, 2015 | 56 | 2015 |
| Stabilization of protein–protein interaction complexes through small molecules B Zarzycka, MA Kuenemann, MA Miteva, GAF Nicolaes, G Vriend, ... Drug Discovery Today 21 (1), 48-57, 2016 | 55 | 2016 |
| Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells L Seidel, B Zarzycka, SA Zaidi, V Katritch, I Coin Elife 6, e27711, 2017 | 54 | 2017 |
| Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor M Audet, KL White, B Breton, B Zarzycka, GW Han, Y Lu, C Gati, A Batyuk, ... Nature chemical biology 15 (1), 11-17, 2019 | 53 | 2019 |
| Contribution of river‐borne soil organic carbon to the Gulf of Lions (NW Mediterranean) JH Kim, B Zarzycka, R Buscail, F Peterse, J Bonnin, W Ludwig, ... Limnology and oceanography 55 (2), 507-518, 2010 | 53 | 2010 |
| In Silico Identification of Potential Cholestasis-Inducing Agents via Modeling of Na+-Dependent Taurocholate Cotransporting Polypeptide Substrate Specificity R Greupink, SB Nabuurs, B Zarzycka, V Verweij, M Monshouwer, ... Toxicological Sciences 129 (1), 35-48, 2012 | 44 | 2012 |
| O-GlcNAc engineering of GPCR peptide-agonists improves their stability and in vivo activity PM Levine, AT Balana, E Sturchler, C Koole, H Noda, B Zarzycka, ... Journal of the American Chemical Society 141 (36), 14210-14219, 2019 | 42 | 2019 |
| A Thieno[2,3-d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor TJ Fyfe, B Zarzycka, HD Lim, B Kellam, SN Mistry, V Katrich, ... Journal of Medicinal Chemistry 62 (1), 174-206, 2018 | 42 | 2018 |
| Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation SABM Aarts, TTP Seijkens, PJH Kusters, SMA van der Pol, B Zarzycka, ... Journal of neuroinflammation 14, 1-14, 2017 | 40 | 2017 |
| Occurrence and abundance of soil‐specific bacterial membrane lipid markers in the Têt watershed (southern France): Soil‐specific BHPs and branched GDGTs JH Kim, HM Talbot, B Zarzycka, T Bauersachs, T Wagner Geochemistry, Geophysics, Geosystems 12 (2), 2011 | 33 | 2011 |
| Structural details of a Class B GPCR-arrestin complex revealed by genetically encoded crosslinkers in living cells Y Aydin, T Böttke, JH Lam, S Ernicke, A Fortmann, M Tretbar, B Zarzycka, ... Nature Communications 14 (1), 1151, 2023 | 30 | 2023 |
| Papain‐specific activating esters in aqueous dipeptide synthesis RJAC de Beer, B Zarzycka, M Mariman, HIV Amatdjais‐Groenen, ... ChemBioChem 13 (9), 1319-1326, 2012 | 19 | 2012 |
| Papain‐Catalyzed Peptide Bond Formation: Enzyme‐Specific Activation with Guanidinophenyl Esters RJAC de Beer, B Zarzycka, HIV Amatdjais‐Groenen, SCB Jans, T Nuijens, ... ChemBioChem 12 (14), 2201-2207, 2011 | 17 | 2011 |
| Targeting the adaptive immune system: new strategies in the treatment of atherosclerosis B Zarzycka, GAF Nicolaes, E Lutgens Expert review of clinical pharmacology 8 (3), 297-313, 2015 | 16 | 2015 |
