| Fibrillin-1 regulates the bioavailability of TGFβ1 SS Chaudhry, SA Cain, A Morgan, SL Dallas, CA Shuttleworth, CM Kielty The Journal of cell biology 176 (3), 355-367, 2007 | 384 | 2007 |
| The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg74 SA Cain, PN Monk Journal of Biological Chemistry 277 (9), 7165-7169, 2002 | 332 | 2002 |
| Elastic fibres in health and disease AK Baldwin, A Simpson, R Steer, SA Cain, CM Kielty Expert reviews in molecular medicine 15, e8, 2013 | 256 | 2013 |
| The chemoattractant receptor-like protein C5L2 binds the C3a des-Arg77/acylation-stimulating protein D Kalant, SA Cain, M Maslowska, AD Sniderman, K Cianflone, PN Monk Journal of Biological Chemistry 278 (13), 11123-11129, 2003 | 250 | 2003 |
| Molecular basis of elastic fiber formation: critical interactions and a tropoelastin-fibrillin-1 cross-link MJ Rock, SA Cain, LJ Freeman, A Morgan, K Mellody, A Marson, ... Journal of Biological Chemistry 279 (22), 23748-23758, 2004 | 205 | 2004 |
| Fibrillin microfibrils and elastic fibre proteins: Functional interactions and extracellular regulation of growth factors J Thomson, M Singh, A Eckersley, SA Cain, MJ Sherratt, C Baldock Seminars in cell & developmental biology 89, 109-117, 2019 | 158 | 2019 |
| Differential regulation of elastic fiber formation by fibulin-4 and-5 R Choudhury, A McGovern, C Ridley, SA Cain, A Baldwin, MC Wang, ... Journal of Biological Chemistry 284 (36), 24553-24567, 2009 | 151 | 2009 |
| Fibrillin-1 interactions with heparin: implications for microfibril and elastic fiber assembly SA Cain, C Baldock, J Gallagher, A Morgan, DV Bax, AS Weiss, ... Journal of Biological Chemistry 280 (34), 30526-30537, 2005 | 130 | 2005 |
| Tropoelastin and elastin assembly J Ozsvar, C Yang, SA Cain, C Baldock, A Tarakanova, AS Weiss Frontiers in bioengineering and biotechnology 9, 643110, 2021 | 115 | 2021 |
| The role of fibrillin and microfibril binding proteins in elastin and elastic fibre assembly ARF Godwin, M Singh, MP Lockhart-Cairns, YF Alanazi, SA Cain, ... Matrix Biology 84, 17-30, 2019 | 115 | 2019 |
| Proteomic analysis of fibrillin‐rich microfibrils SA Cain, A Morgan, MJ Sherratt, SG Ball, CA Shuttleworth, CM Kielty Proteomics 6 (1), 111-122, 2006 | 112 | 2006 |
| Pharmacological characterization of antagonists of the C5a receptor NJ Paczkowski, AM Finch, JB Whitmore, AJ Short, AK Wong, PN Monk, ... British journal of pharmacology 128 (7), 1461-1466, 1999 | 110 | 1999 |
| Homotypic fibrillin-1 interactions in microfibril assembly A Marson, MJ Rock, SA Cain, LJ Freeman, A Morgan, K Mellody, ... Journal of Biological Chemistry 280 (6), 5013-5021, 2005 | 107 | 2005 |
| Cell adhesion to fibrillin-1: identification of an Arg-Gly-Asp-dependent synergy region and a heparin-binding site that regulates focal adhesion formation DV Bax, Y Mahalingam, S Cain, K Mellody, L Freeman, K Younger, ... Journal of cell science 120 (8), 1383-1392, 2007 | 106 | 2007 |
| Complement C3a receptors in the pituitary gland: a novel pathway by which an innate immune molecule releases hormones involved in the control of inflammation K Francis, BM Lewis, H Akatsu, PN Monk, SA Cain, MF Scanlon, ... The FASEB journal 17 (15), 2266-2268, 2003 | 100 | 2003 |
| Coacervation is promoted by molecular interactions between the PF2 segment of fibrillin-1 and the domain 4 region of tropoelastin AW Clarke, SG Wise, SA Cain, CM Kielty, AS Weiss Biochemistry 44 (30), 10271-10281, 2005 | 77 | 2005 |
| Heparan sulfate regulates fibrillin-1 N-and C-terminal interactions SA Cain, AK Baldwin, Y Mahalingam, B Raynal, TA Jowitt, ... Journal of Biological Chemistry 283 (40), 27017-27027, 2008 | 69 | 2008 |
| Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions SA Cain, A McGovern, AK Baldwin, C Baldock, CM Kielty PloS one 7 (11), e48634, 2012 | 66 | 2012 |
| Nanostructure of fibrillin-1 reveals compact conformation of EGF arrays and mechanism for extensibility C Baldock, V Siegler, DV Bax, SA Cain, KT Mellody, A Marson, JL Haston, ... Proceedings of the National Academy of Sciences 103 (32), 11922-11927, 2006 | 65 | 2006 |
| Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site A Higginbottom, SA Cain, TM Woodruff, LM Proctor, PK Madala, ... Journal of Biological Chemistry 280 (18), 17831-17840, 2005 | 64 | 2005 |
Clair BaldockProfessor of Biochemistry, University of ManchesterVerified email at manchester.ac.uk