Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra TO Crișan, MCP Cleophas, M Oosting, H Lemmers, H Toenhake-Dijkstra, ... Annals of the rheumatic diseases 75 (4), 755-762, 2016 | 281 | 2016 |
Inflammasome-independent modulation of cytokine response by autophagy in human cells TO Crişan, TS Plantinga, FL van de Veerdonk, MF Farcaş, M Stoffels, ... PloS one 6 (4), e18666, 2011 | 230 | 2011 |
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2 TS Plantinga, TO Crisan, M Oosting, FL van de Veerdonk, DJ de Jong, ... Gut 60 (9), 1229-1235, 2011 | 219 | 2011 |
Asymptomatic hyperuricaemia: a silent activator of the innate immune system LAB Joosten, TO Crişan, P Bjornstad, RJ Johnson Nature Reviews Rheumatology 16 (2), 75-86, 2020 | 185 | 2020 |
Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia G Cabău, TO Crișan, V Klück, RA Popp, LAB Joosten Immunological reviews 294 (1), 92-105, 2020 | 182 | 2020 |
Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway TO Crişan, MCP Cleophas, B Novakovic, K Erler, FL van de Veerdonk, ... Proceedings of the National Academy of Sciences 114 (21), 5485-5490, 2017 | 164 | 2017 |
Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases MCP Cleophas, TO Crişan, H Lemmers, H Toenhake-Dijkstra, G Fossati, ... Annals of the rheumatic diseases 75 (3), 593-600, 2016 | 129 | 2016 |
Innate immune memory: implications for host responses to damage‐associated molecular patterns TO Crișan, MG Netea, LAB Joosten European journal of immunology 46 (4), 817-828, 2016 | 113 | 2016 |
Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals EE Mylona, M Mouktaroudi, TO Crisan, S Makri, A Pistiki, M Georgitsi, ... Arthritis research & therapy 14, 1-10, 2012 | 97 | 2012 |
Factors modulating the inflammatory response in acute gouty arthritis MC Cleophas, TO Crişan, LAB Joosten Current opinion in rheumatology 29 (2), 163-170, 2017 | 74 | 2017 |
Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra LAB Joosten, TO Crişan, T Azam, MCP Cleophas, MI Koenders, ... Annals of the rheumatic diseases 75 (6), 1219-1227, 2016 | 72 | 2016 |
Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout V Klück, RC van Deuren, G Cavalli, A Shaukat, P Arts, MC Cleophas, ... Annals of the rheumatic diseases 79 (4), 536-544, 2020 | 60 | 2020 |
Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression MCP Cleophas, TO Crişan, V Klück, N Hoogerbrugge, RT Netea-Maier, ... Arthritis Research & Therapy 21, 1-11, 2019 | 38 | 2019 |
Lysine methyltransferase G9a is an important modulator of trained immunity VP Mourits, JH van Puffelen, B Novakovic, M Bruno, AV Ferreira, ... Clinical & translational immunology 10 (2), e1253, 2021 | 31 | 2021 |
Trained immunity and inflammation in rheumatic diseases M Badii, O Gaal, RA Popp, TO Crișan, LAB Joosten Joint Bone Spine 89 (4), 105364, 2022 | 30 | 2022 |
Novel concepts in systemic sclerosis pathogenesis: role for miRNAs I Szabo, L Muntean, T Crisan, V Rednic, C Sirbe, S Rednic Biomedicines 9 (10), 1471, 2021 | 26 | 2021 |
Urate-induced epigenetic modifications in myeloid cells M Badii, OI Gaal, MC Cleophas, V Klück, R Davar, E Habibi, ST Keating, ... Arthritis Research & Therapy 23, 1-11, 2021 | 24 | 2021 |
Absence of BRAF V600E mutation in a cohort of 402 patients with various chronic and acute myeloid neoplasms AP Trifa, RA Popp, A Cucuianu, CA Coadă, LG Urian, MS Militaru, ... Leukemia & Lymphoma 53 (12), 2496-2497, 2012 | 19 | 2012 |
Association of gout polygenic risk score with age at disease onset and Tophaceous disease in European and Polynesian men with gout NA Sumpter, R Takei, M Cadzow, RKG Topless, AJ Phipps‐Green, ... Arthritis & Rheumatology 75 (5), 816-825, 2023 | 15 | 2023 |
New gout test: enhanced ex vivo cytokine production from PBMCS in common gout patients and a gout patient with Kearns-Sayre syndrome TL Jansen, D Berendsen, TO Crisan, MCP Cleophas, MCH Janssen, ... Clinical rheumatology 33, 1341-1346, 2014 | 13 | 2014 |