Key topics in molecular docking for drug design PHM Torres, ACR Sodero, P Jofily, FP Silva-Jr International journal of molecular sciences 20 (18), 4574, 2019 | 590 | 2019 |
Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as α-Glucosidases Inhibitors SB Ferreira, ACR Sodero, MFC Cardoso, ES Lima, CR Kaiser, FP Silva Jr, ... Journal of medicinal chemistry 53 (6), 2364-2375, 2010 | 318 | 2010 |
Evaluation of the energy expenditure in competitive swimming strokes TM Barbosa, R Fernandes, KL Keskinen, P Colaço, C Cardoso, J Silva, ... International journal of sports medicine 27 (11), 894-899, 2006 | 225 | 2006 |
In silico Strategies to Support Fragment-to-Lead Optimization in Drug Discovery LR de Souza Neto, JT Moreira-Filho, BJ Neves, RLBR Maidana, ... Frontiers in chemistry 8, 93, 2020 | 220 | 2020 |
The diverse mechanisms and anticancer potential of naphthoquinones CE Pereyra, RF Dantas, SB Ferreira, LP Gomes, FP Silva-Jr Cancer Cell International 19, 1-20, 2019 | 181 | 2019 |
Filtering promiscuous compounds in early drug discovery: is it a good idea? MR Senger, CAM Fraga, RF Dantas, FP Silva Jr Drug Discovery Today 21 (6), 868-872, 2016 | 103 | 2016 |
Treatment by testicular sperm extraction and intracytoplasmic sperm injection of 65 azoospermic patients with non‐mosaic Klinefelter syndrome with birth of 17 healthy children C Madureira, M Cunha, M Sousa, AP Neto, MJ Pinho, P Viana, ... Andrology 2 (4), 623-631, 2014 | 95 | 2014 |
Zoneamento para planejamento ambiental: vantagens e restrições de métodos e técnicas. J Silva, RF dos SANTOS | 77 | 2004 |
1-Phenyl-1H-and 2-phenyl-2H-1, 2, 3-triazol derivatives: Design, synthesis and inhibitory effect on alpha-glycosidases D Gonzaga, MR Senger, FC Da Silva, VF Ferreira, FP Silva-Jr European Journal of Medicinal Chemistry 74, 461-476, 2014 | 76 | 2014 |
Isolation and expression of a hypotensive and anti-platelet acidic phospholipase A2 from Bothrops moojeni snake venom LB Silveira, DP Marchi-Salvador, NA Santos-Filho, FP Silva Jr, S Marcussi, ... Journal of pharmaceutical and biomedical analysis 73, 35-43, 2013 | 74 | 2013 |
Exploring the DNA binding/cleavage, cellular accumulation and topoisomerase inhibition of 2-hydroxy-3-(aminomethyl)-1, 4-naphthoquinone Mannich bases and their platinum (II … AP Neves, MXG Pereira, EJ Peterson, R Kipping, MD Vargas, FP Silva-Jr, ... Journal of inorganic biochemistry 119, 54-64, 2013 | 69 | 2013 |
De novo design and bioactivity prediction of SARS-CoV-2 main protease inhibitors using recurrent neural network-based transfer learning MVS Santana, FP Silva-Jr BMC chemistry 15 (1), 8, 2021 | 67 | 2021 |
Molecular characterization of an acidic phospholipase A2 from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region SS Teixeira, LB Silveira, FMN da Silva, DP Marchi-Salvador, FP Silva, ... Archives of toxicology 85, 1219-1233, 2011 | 66 | 2011 |
Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin FC Cadoná, RF Dantas, GH de Mello, FP Silva-Jr Critical Reviews in Food Science and Nutrition 62 (26), 7222-7241, 2022 | 64 | 2022 |
Enzymatic and structural characterization of a basic phospholipase A2 from the sea anemone Condylactis gigantea L Romero, S Marcussi, DP Marchi-Salvador, FP Silva Jr, AL Fuly, ... Biochimie 92 (8), 1063-1071, 2010 | 64 | 2010 |
Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice RB de Oliveira, MR Senger, LM Vasques, J Gasparotto, JPA dos Santos, ... International journal for parasitology 43 (5), 371-379, 2013 | 61 | 2013 |
Kinetics Studies on the Inhibition Mechanism of Pancreatic α‐Amylase by Glycoconjugated 1H‐1,2,3‐Triazoles: A New Class of Inhibitors with Hypoglycemiant … MR Senger, LCA Gomes, SB Ferreira, CR Kaiser, VF Ferreira, FP Silva Jr ChemBioChem 13 (11), 1584-1593, 2012 | 60 | 2012 |
Trypanosomatidae peptidases: a target for drugs development A Beatriz Vermelho, S Giovanni De Simone, C Masini d'Avila-Levy, ... Current Enzyme Inhibition 3 (1), 19-48, 2007 | 60 | 2007 |
Thermostability improvement of Orpinomyces sp. xylanase by directed evolution LM Trevizano, RZ Ventorim, ST de Rezende, FPS Junior, VM Guimarães Journal of Molecular Catalysis B: Enzymatic 81, 12-18, 2012 | 57 | 2012 |
QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni CC Melo-Filho, RF Dantas, RC Braga, BJ Neves, MR Senger, ... Journal of chemical information and modeling 56 (7), 1357-1372, 2016 | 56 | 2016 |