| Circulating extracellular DNA levels are acutely elevated in ischaemic stroke and associated with innate immune system activation GC O’Connell, AB Petrone, CS Tennant, N Lucke-Wold, Y Kabbani, ... Brain Injury 31 (10), 1369-1375, 2017 | 74 | 2017 |
| Machine-learning approach identifies a pattern of gene expression in peripheral blood that can accurately detect ischaemic stroke GC O’Connell, AB Petrone, MB Treadway, CS Tennant, N Lucke-Wold, ... NPJ Genomic Medicine 1 (1), 1-9, 2016 | 63 | 2016 |
| The role of arginase 1 in post-stroke immunosuppression and ischemic stroke severity AB Petrone, GC O’Connell, MD Regier, PD Chantler, JW Simpkins, ... Translational stroke research 7, 103-110, 2016 | 57 | 2016 |
| High interspecimen variability in nucleic acid extraction efficiency necessitates the use of spike-in control for accurate qPCR-based measurement of plasma cell-free DNA levels GC O’Connell, PD Chantler, TL Barr Laboratory Medicine 48 (4), 332-338, 2017 | 52 | 2017 |
| Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage GC O’Connell, ML Alder, CG Smothers, CH Still, AR Webel, SM Moore Neurological research 42 (4), 346-353, 2020 | 38 | 2020 |
| Peripheral blood AKAP7 expression as an early marker for lymphocyte-mediated post-stroke blood brain barrier disruption GC O’Connell, MB Treadway, AB Petrone, CS Tennant, N Lucke-Wold, ... Scientific Reports 7 (1), 1172, 2017 | 38 | 2017 |
| Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkers GC O’Connell, CG Smothers, C Winkelman Brain injury 34 (7), 965-974, 2020 | 37 | 2020 |
| Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population GC O'Connell, PD Chantler, TL Barr Genomics data 14, 47-52, 2017 | 35 | 2017 |
| Monocyte-lymphocyte cross-communication via soluble CD163 directly links innate immune system activation and adaptive immune system suppression following ischemic stroke GC O’Connell, CS Tennant, N Lucke-Wold, Y Kabbani, AR Tarabishy, ... Scientific reports 7 (1), 12940, 2017 | 35 | 2017 |
| Neuro biomarker levels measured with high-sensitivity digital ELISA differ between serum and plasma GC O'Connell, ML Alder, AR Webel, SM Moore Bioanalysis 11 (22), 2087-2094, 2019 | 33 | 2019 |
| Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha GC O'Connell, EE Pistilli Biochemical and biophysical research communications 458 (3), 614-619, 2015 | 30 | 2015 |
| Diagnostic accuracy of blood biomarkers for Alzheimer’s disease and amnestic mild cognitive impairment: A meta-analysis YR Chen, CS Liang, H Chu, J Voss, XL Kang, G O'Connell, HJ Jen, D Liu, ... Ageing Research Reviews 71, 101446, 2021 | 26 | 2021 |
| Diagnosis of ischemic stroke using circulating levels of brain-specific proteins measured via high-sensitivity digital ELISA GC O'Connell, ML Alder, CG Smothers, CH Still, AR Webel, SM Moore Brain research 1739, 146861, 2020 | 21 | 2020 |
| Shifts in leukocyte counts drive the differential expression of transcriptional stroke biomarkers in whole blood GC O’Connell, MB Treadway, CS Tennant, N Lucke-Wold, PD Chantler, ... Translational stroke research 10, 26-35, 2019 | 21 | 2019 |
| Muscle-specific deletion of exons 2 and 3 of the IL15RA gene in mice: effects on contractile properties of fast and slow muscles G O'Connell, G Guo, J Stricker, LBS Quinn, A Ma, EE Pistilli Journal of Applied Physiology 118 (4), 437-448, 2015 | 21 | 2015 |
| Leukocyte dynamics influence reference gene stability in whole blood: data-driven qRT-PCR normalization is a robust alternative for measurement of transcriptional biomarkers GC O’Connell, MB Treadway, AB Petrone, CS Tennant, N Lucke-Wold, ... Laboratory Medicine 48 (4), 346-356, 2017 | 17 | 2017 |
| Analysis of early stroke-induced changes in circulating leukocyte counts using transcriptomic deconvolution GC O’Connell, JHC Chang Translational neuroscience 9 (1), 161-166, 2018 | 16 | 2018 |
| IL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genome GC O'Connell, C Nichols, G Guo, TL Croston, D Thapa, JM Hollander, ... Mitochondrion 25, 87-97, 2015 | 13 | 2015 |
| Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts GC O’Connell, KB Walsh, CG Smothers, S Ruksakulpiwat, BL Armentrout, ... BMC neurology 22 (1), 206, 2022 | 12 | 2022 |
| High-throughput profiling of circulating antibody signatures for stroke diagnosis using small volumes of whole blood GC O'Connell, P Stafford, KB Walsh, O Adeoye, TL Barr Neurotherapeutics 16 (3), 868-877, 2019 | 11 | 2019 |
