Lipogenesis inhibitors: therapeutic opportunities and challenges B Batchuluun, SL Pinkosky, GR Steinberg Nature Reviews Drug Discovery 21 (4), 283-305, 2022 | 253 | 2022 |
Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD (P) H oxidase pathway in human aortic endothelial cells B Batchuluun, T Inoguchi, N Sonoda, S Sasaki, T Inoue, Y Fujimura, ... Atherosclerosis 232 (1), 156-164, 2014 | 181 | 2014 |
Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia MR Morrow, B Batchuluun, J Wu, E Ahmadi, JM Leroux, ... Cell Metabolism 34 (6), 919-936. e8, 2022 | 120 | 2022 |
Elevated medium-chain acylcarnitines are associated with gestational diabetes mellitus and early progression to type 2 diabetes and induce pancreatic β-cell dysfunction B Batchuluun, D Al Rijjal, KJ Prentice, JA Eversley, E Burdett, H Mohan, ... Diabetes 67 (5), 885-897, 2018 | 117 | 2018 |
GDF15 promotes weight loss by enhancing energy expenditure in muscle D Wang, LK Townsend, GJ DesOrmeaux, SM Frangos, B Batchuluun, ... Nature 619 (7968), 143-150, 2023 | 108 | 2023 |
Characterization of zinc influx transporters (ZIPs) in pancreatic β cells: roles in regulating cytosolic zinc homeostasis and insulin secretion Y Liu, B Batchuluun, L Ho, D Zhu, KJ Prentice, A Bhattacharjee, M Zhang, ... Journal of Biological Chemistry 290 (30), 18757-18769, 2015 | 88 | 2015 |
GABA promotes β‐cell proliferation, but does not overcome impaired glucose homeostasis associated with diet‐induced obesity A Untereiner, S Abdo, A Bhattacharjee, H Gohil, F Pourasgari, N Ibeh, ... The FASEB Journal 33 (3), 3968-3984, 2019 | 69 | 2019 |
The discovery of novel predictive biomarkers and early-stage pathophysiology for the transition from gestational diabetes to type 2 diabetes SR Khan, H Mohan, Y Liu, B Batchuluun, H Gohil, D Al Rijjal, ... Diabetologia 62, 687-703, 2019 | 63 | 2019 |
Rapid elevation in CMPF may act as a tipping point in diabetes development Y Liu, KJ Prentice, JA Eversley, C Hu, B Batchuluun, K Leavey, ... Cell reports 14 (12), 2889-2900, 2016 | 62 | 2016 |
Direct AMPK activation corrects NASH in rodents through metabolic effects and direct action on inflammation and fibrogenesis P Gluais‐Dagorn, M Foretz, GR Steinberg, B Batchuluun, ... Hepatology Communications 6 (1), 101-119, 2022 | 60 | 2022 |
CTLA-4Ig immunotherapy of obesity-induced insulin resistance by manipulation of macrophage polarization in adipose tissues M Fujii, T Inoguchi, B Batchuluun, N Sugiyama, K Kobayashi, N Sonoda, ... Biochemical and biophysical research communications 438 (1), 103-109, 2013 | 53 | 2013 |
FXR in the dorsal vagal complex is sufficient and necessary for upper small intestinal microbiome-mediated changes of TCDCA to alter insulin action in rats SY Zhang, RJW Li, YM Lim, B Batchuluun, H Liu, TMZ Waise, TKT Lam Gut 70 (9), 1675-1683, 2021 | 39 | 2021 |
A novel GLP1 receptor interacting protein ATP6ap2 regulates insulin secretion in pancreatic beta cells FF Dai, A Bhattacharjee, Y Liu, B Batchuluun, M Zhang, XS Wang, ... Journal of Biological Chemistry 290 (41), 25045-25061, 2015 | 34 | 2015 |
Synthesis and characterization of urofuranoic acids: in vivo metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid (CMPF) and effects on in vitro insulin … E Nagy, Y Liu, KJ Prentice, KW Sloop, PE Sanders, B Batchuluun, ... Journal of Medicinal Chemistry 60 (5), 1860-1875, 2017 | 33 | 2017 |
An abbreviated protocol for in vitro generation of functional human embryonic stem cell-derived beta-like cells M Massumi, F Pourasgari, A Nalla, B Batchuluun, K Nagy, E Neely, R Gull, ... PLoS One 11 (10), e0164457, 2016 | 29 | 2016 |
Serum ferritin level is higher in poorly controlled patients with type 2 diabetes and people without diabetes, aged over 55 years B Batchuluun, T Matsumata, B Batchuluun, N Erdenebileg, ... Diabetic medicine 31 (4), 419-424, 2014 | 24 | 2014 |
The cardiovascular effects of metformin: conventional and new insights B Batchuluun, N Sonoda, R Takayanagi, T Inoguchi J Endocrinol Diabetes Obes 2 (2), 1035, 2014 | 22 | 2014 |
3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid (CMPF) prevents high fat diet‐induced insulin resistance via maintenance of hepatic lipid homeostasis H Mohan, SL Brandt, JH Kim, F Wong, M Lai, KJ Prentice, D Al Rijjal, ... Diabetes, Obesity and Metabolism 21 (1), 61-72, 2019 | 21 | 2019 |
Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice EM Desjardins, J Wu, DCT Lavoie, E Ahmadi, LK Townsend, MR Morrow, ... Cell Reports Medicine 4 (9), 2023 | 12 | 2023 |
Fatty acids increase GDF15 and reduce food intake through a GFRAL signaling axis D Wang, MJT Jabile, J Lu, LK Townsend, CM Valvano, J Gautam, ... Diabetes 73 (1), 51-56, 2024 | 11 | 2024 |