| IL-6/JAK/STAT3 signaling in breast cancer metastasis: biology and treatment SG Manore, DL Doheny, GL Wong, HW Lo Frontiers in oncology 12, 866014, 2022 | 177 | 2022 |
| Hedgehog signaling and truncated GLI1 in cancer D Doheny, SG Manore, GL Wong, HW Lo Cells 9 (9), 2114, 2020 | 155 | 2020 |
| TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment SR Sirkisoon, RL Carpenter, T Rimkus, D Doheny, D Zhu, NR Aguayo, ... Oncogene 39 (1), 64-78, 2020 | 89 | 2020 |
| Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis D Doheny, S Sirkisoon, RL Carpenter, NR Aguayo, AT Regua, ... Oncogene 39 (42), 6589-6605, 2020 | 72 | 2020 |
| STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges GL Wong, SG Manore, DL Doheny, HW Lo Seminars in cancer biology 86, 84-106, 2022 | 59 | 2022 |
| Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→ CNTF axis to promote progression of brain … SR Sirkisoon, GL Wong, NR Aguayo, DL Doheny, D Zhu, AT Regua, ... Cancer letters 540, 215726, 2022 | 38 | 2022 |
| Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis B Foley, DL Doheny, MB Black, SN Pendse, BA Wetmore, RA Clewell, ... Toxicological Sciences 155 (1), 85-100, 2017 | 37 | 2017 |
| Transgenic mouse models of breast cancer AT Regua, A Arrigo, D Doheny, GL Wong, HW Lo Cancer letters 516, 73-83, 2021 | 18 | 2021 |
| Trk receptor tyrosine kinases in metastasis and cancer therapy AT Regua, DL Doheny, AB Arrigo, HW Lo Discovery Medicine 28 (154), 195-203, 2019 | 17 | 2019 |
| The role of fit-for-purpose assays within tiered testing approaches: a case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay T Beames, M Moreau, LA Roberts, K Mansouri, S Haider, M Smeltz, ... Toxicology and Applied Pharmacology 387, 114774, 2020 | 16 | 2020 |
| An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis JK Hartman, T Beames, B Parks, D Doheny, G Song, A Efremenko, ... Toxicology and applied pharmacology 355, 112-126, 2018 | 15 | 2018 |
| TrkA interacts with and phosphorylates STAT3 to enhance gene transcription and promote breast cancer stem cells in triple-negative and HER2-enriched breast cancers AT Regua, NR Aguayo, SA Jalboush, DL Doheny, SG Manore, D Zhu, ... Cancers 13 (10), 2340, 2021 | 14 | 2021 |
| An FDA-approved antifungal, ketoconazole, and its novel derivative suppress tGLI1-mediated breast cancer brain metastasis by inhibiting the DNA-binding activity of brain … D Doheny, S Manore, SR Sirkisoon, D Zhu, NR Aguayo, A Harrison, ... Cancers 14 (17), 4256, 2022 | 11 | 2022 |
| Editor’s Highlight: Development of an In vitro Assay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety Assessment MM Miller, RA Alyea, C LeSommer, DL Doheny, SM Rowley, KM Childs, ... Toxicological Sciences 154 (1), 162-173, 2016 | 11 | 2016 |
| NEDD4 degrades TUSC2 to promote glioblastoma progression TK Rimkus, AB Arrigo, D Zhu, RL Carpenter, S Sirkisoon, D Doheny, ... Cancer letters 531, 124-135, 2022 | 8 | 2022 |
| Hedgehog signaling and truncated GLI1 in cancer. Cells 9: 2114 D Doheny, SG Manore, GL Wong, HW Lo | 7 | 2020 |
| Hedgehog signaling and truncated GLI1 in cancer. Cells. 2020; 9: 2114 D Doheny, SG Manore, GL Wong, HW Lo | 6 | |
| Targeting tGLI1 pharmacologically as a new therapeutic strategy for breast cancer brain metastases D Doheny, S Manore, GL Wong, D Zhu, S Sirkisoon, M Anguelov, ... Cancer Research 82 (12_Supplement), 2433-2433, 2022 | 1 | 2022 |
| Antifungal ketoconazole inhibits tumor-specific transcription factor tGLI1 leading to suppression of breast cancer stem cells and brain metastasis DL Doheny, SR Sirkisoon, T Rimkus, D Zhu, NR Aguayo, A Harrison, ... Cancer Research 80 (16_Supplement), 5025-5025, 2020 | 1 | 2020 |
| BSCI-02. tGLI1 is a novel, actionable target for the treatment of breast cancer brain metastases D Doheny, S Sirkisoon, T Rimkus, D Zhu, N Aguayo, A Harrison, ... Neuro-Oncology Advances 1 (Supplement_1), i1-i1, 2019 | 1 | 2019 |
