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Michael William Beck
Michael William Beck
Assistant Professor, Department of Chemistry and Biochemistry, Eastern Illinois University
Verified email at EIU.edu - Homepage
Title
Cited by
Cited by
Year
Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease
MW Beck, JS Derrick, RA Kerr, SB Oh, WJ Cho, SJC Lee, Y Ji, J Han, ...
Nature Communications 7 (1), 13115, 2016
862016
A rationally designed small molecule for identifying an in vivo link between metal–amyloid-β complexes and the pathogenesis of Alzheimer's disease
MW Beck, SB Oh, RA Kerr, HJ Lee, SH Kim, S Kim, M Jang, BT Ruotolo, ...
Chemical Science 6 (3), 1879-1886, 2015
772015
Reactivity of diphenylpropynone derivatives toward metal-associated amyloid-β species
AS Pithadia, A Kochi, MT Soper, MW Beck, Y Liu, S Lee, AS DeToma, ...
Inorganic chemistry 51 (23), 12959-12967, 2012
522012
Tuning reactivity of diphenylpropynone derivatives with metal-associated amyloid-β species via structural modifications
Y Liu, A Kochi, AS Pithadia, S Lee, Y Nam, MW Beck, X He, D Lee, ...
Inorganic chemistry 52 (14), 8121-8130, 2013
412013
Human carboxylesterases and fluorescent probes to image their activity in live cells
A Singh, M Gao, MW Beck
RSC Medicinal Chemistry 12 (7), 1142-1153, 2021
342021
Michael addition-based probes for ratiometric fluorescence imaging of protein S-depalmitoylases in live cells and tissues
MW Beck, RS Kathayat, CM Cham, EB Chang, BC Dickinson
Chemical science 8 (11), 7588-7592, 2017
312017
A Fluorescent Probe with Improved Water Solubility Permits the Analysis of Protein S-Depalmitoylation Activity in Live Cells
T Qiu, RS Kathayat, Y Cao, MW Beck, BC Dickinson
Biochemistry 57 (2), 221-225, 2018
242018
Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease
MW Beck, JS Derrick, JM Suh, M Kim, KJ Korshavn, RA Kerr, WJ Cho, ...
ChemMedChem 12 (22), 1828-1838, 2017
172017
Ligand Design to Target and Modulate Metal–Protein Interactions in Neurodegenerative Diseases
MW Beck, AS Pithadia, AS DeToma, KJ Korshavn, MH Lim
Ligand Design in Medicinal Inorganic Chemistry, 257-286, 2014
62014
Carbonate‐Based Fluorescent Chemical Tool for Uncovering Carboxylesterase 1 (CES1) Activity Variations in Live Cells
A Singh, M Gao, CJ Karns, TP Spidle, MW Beck
ChemBioChem 23 (12), e202200069, 2022
42022
Fluorogenic chemical tools to shed light on CES1-mediated adverse drug interactions
CJ Karns, TP Spidle, E Adusah, M Gao, JE Nehls, MW Beck
Chemical Communications, 2024
12024
Fluorescein Diacetate (FDA) Should Not Be Used to Study Human Carboxylesterase 2 (CES2) in Complex Biological Systems Without Validation
CJ Karns, A Singh, MR Walk, E Adusah, AM Pearson, MW Beck
2025
Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods
BC Dickinson, RS Kathayat, MW Beck
US Patent 10,413,583, 2019
2019
Front Cover: Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease (ChemMedChem 22/2017)
MW Beck, JS Derrick, JM Suh, M Kim, KJ Korshavn, RA Kerr, WJ Cho, ...
ChemMedChem 12 (22), 1818-1818, 2017
2017
Development of Small Molecules as Chemical Tools for Investigating the Role of Metal-Protein Interactions in Neurodegenerative Diseases.
MW Beck
2015
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