NMDAR inhibition-independent antidepressant actions of ketamine metabolites P Zanos, R Moaddel, PJ Morris, P Georgiou, J Fischell, GI Elmer, ... Nature 533 (7604), 481-486, 2016 | 1603 | 2016 |
Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms P Zanos, R Moaddel, PJ Morris, LM Riggs, JN Highland, P Georgiou, ... Pharmacological reviews 70 (3), 621-660, 2018 | 1154 | 2018 |
(2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions P Zanos, JN Highland, BW Stewart, P Georgiou, CE Jenne, J Lovett, ... Proceedings of the National Academy of Sciences 116 (13), 6441-6450, 2019 | 146 | 2019 |
The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice P Zanos, P Georgiou, SR Wright, SM Hourani, I Kitchen, ... Neuropsychopharmacology 39 (4), 855-865, 2014 | 146 | 2014 |
Glutamatergic ventral pallidal neurons modulate activity of the habenula–tegmental circuitry and constrain reward seeking J Tooley, L Marconi, JB Alipio, B Matikainen-Ankney, P Georgiou, ... Biological psychiatry 83 (12), 1012-1023, 2018 | 142 | 2018 |
Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor P Georgiou, P Zanos, TCM Mou, X An, DM Gerhard, DI Dryanovski, ... Nature neuroscience 25 (9), 1191-1200, 2022 | 115 | 2022 |
A negative allosteric modulator for α5 subunit-containing GABA receptors exerts a rapid and persistent antidepressant-like action without the side effects of the NMDA receptor … P Zanos, ME Nelson, JN Highland, SR Krimmel, P Georgiou, TD Gould, ... eneuro 4 (1), 2017 | 106* | 2017 |
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS–FTD-linked UBQLN2 mutations NTT Le, L Chang, I Kovlyagina, P Georgiou, N Safren, KE Braunstein, ... Proceedings of the National Academy of Sciences 113 (47), E7580-E7589, 2016 | 102 | 2016 |
Animal models to improve our understanding and treatment of suicidal behavior TD Gould, P Georgiou, LA Brenner, L Brundin, A Can, P Courtet, ... Translational psychiatry 7 (4), e1092-e1092, 2017 | 96 | 2017 |
(R)‐Ketamine exerts antidepressant actions partly via conversion to (2R,6R)‐hydroxynorketamine, while causing adverse effects at sub‐anaesthetic doses P Zanos, JN Highland, X Liu, TA Troppoli, P Georgiou, J Lovett, PJ Morris, ... British journal of pharmacology 176 (14), 2573-2592, 2019 | 81 | 2019 |
Hydroxynorketamines: pharmacology and potential therapeutic applications JN Highland, P Zanos, LM Riggs, P Georgiou, SM Clark, PJ Morris, ... Pharmacological reviews 73 (2), 763-791, 2021 | 79 | 2021 |
Dopamine and stress system modulation of sex differences in decision making P Georgiou, P Zanos, S Bhat, JK Tracy, IJ Merchenthaler, MM McCarthy, ... Neuropsychopharmacology 43 (2), 313-324, 2018 | 79 | 2018 |
Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent mechanism P Zanos, SR Wright, P Georgiou, JH Yoo, C Ledent, SM Hourani, I Kitchen, ... Pharmacology Biochemistry and Behavior 119, 72-79, 2014 | 65 | 2014 |
Oxytocin and opioid addiction revisited: old drug, new applications P Zanos, P Georgiou, C Weber, F Robinson, C Kouimtsidis, ... British journal of pharmacology 175 (14), 2809-2824, 2018 | 57 | 2018 |
Group II metabotropic glutamate receptor blockade promotes stress resilience in mice JN Highland, P Zanos, P Georgiou, TD Gould Neuropsychopharmacology 44 (10), 1788-1796, 2019 | 56 | 2019 |
Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype P Georgiou, P Zanos, JA Garcia-Carmona, S Hourani, I Kitchen, ... Neuropharmacology 105, 520-532, 2016 | 55 | 2016 |
The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems P Georgiou, P Zanos, JA Garcia-Carmona, S Hourani, I Kitchen, BL Kieffer, ... European Neuropsychopharmacology 25 (12), 2459-2464, 2015 | 54 | 2015 |
NMDA receptor activation-dependent antidepressant-relevant behavioral and synaptic actions of ketamine P Zanos, KA Brown, P Georgiou, P Yuan, CA Zarate, SM Thompson, ... Journal of Neuroscience 43 (6), 1038-1050, 2023 | 53 | 2023 |
Environmental enrichment enhances conditioned place preference to ethanol via an oxytocinergic-dependent mechanism in male mice M Rae, P Zanos, P Georgiou, P Chivers, A Bailey, R Camarini Neuropharmacology 138, 267-274, 2018 | 53 | 2018 |
Differential regulation of mGlu5R and ΜOPr by priming‐ and cue‐induced reinstatement of cocaine‐seeking behaviour in mice P Georgiou, P Zanos, M Ehteramyan, S Hourani, I Kitchen, R Maldonado, ... Addiction biology 20 (5), 902-912, 2015 | 47 | 2015 |