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Yuan Hong
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Human organoids in basic research and clinical applications
XY Tang, S Wu, D Wang, C Chu, Y Hong, M Tao, H Hu, M Xu, X Guo, ...
Signal transduction and targeted therapy 7 (1), 168, 2022
2632022
DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome
XY Tang, L Xu, J Wang, Y Hong, Y Wang, Q Zhu, D Wang, XY Zhang, ...
The Journal of Clinical Investigation 131 (12), 2021
942021
Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease
C Liu, Z Fu, S Wu, X Wang, S Zhang, C Chu, Y Hong, W Wu, S Chen, ...
EMBO Molecular Medicine 14 (7), e15851, 2022
382022
Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C
K Lu, Y Hong, M Tao, L Shen, Z Zheng, K Fang, F Yuan, M Xu, C Wang, ...
EMBO molecular medicine 15 (1), e16364, 2023
322023
Abnormal mitochondria in Down syndrome iPSC-derived GABAergic interneurons and organoids
L Xu, HQ Huo, KQ Lu, XY Tang, Y Hong, X Han, ZX Fu, KH Fang, M Xu, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (6), 166388, 2022
212022
Dysfunction of vesicular storage in young-onset Parkinson's patient-derived dopaminergic neurons and organoids revealed by single cell electrochemical cytometry
W Zhu, M Tao, Y Hong, S Wu, C Chu, Z Zheng, X Han, Q Zhu, M Xu, ...
Chemical Science 13 (21), 6217-6223, 2022
182022
LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons
F Yuan, KH Fang, Y Hong, SB Xu, M Xu, Y Pan, Y Liu
Protein & Cell 11 (4), 286-291, 2020
162020
Identification of small molecules for accelerating the differentiation of GABA interneurons from human pluripotent stem cells
L Shen, F Yuan, Y Hong, M Xu, Y Hu, Y Liu
Journal of Molecular Cell Biology 12 (3), 245-248, 2020
72020
Construction of human 3D striato-nigral assembloids to recapitulate medium spiny neuronal projection defects in Huntington’s disease
S Wu, Y Hong, C Chu, Y Gan, X Li, M Tao, D Wang, H Hu, Z Zheng, Q Zhu, ...
Proceedings of the National Academy of Sciences 121 (22), e2316176121, 2024
62024
Modeling maternal cholesterol exposure reveals a reduction of neural progenitor proliferation using human cerebral organoids
P Fan, Y Wang, K Lu, Y Hong, M Xu, X Han, Y Liu
Life Medicine 2 (2), lnac034, 2023
52023
Single‐Cell Transcriptome Landscape and Cell Fate Decoding in Human Brain Organoids after Transplantation
SB Xu, XR Li, P Fan, X Li, Y Hong, X Han, S Wu, C Chu, Y Chen, M Xu, ...
Advanced Science, 2402287, 2024
42024
circFKBP8 (5S, 6)-encoded protein as a novel endogenous regulator in major depressive disorder by inhibiting glucocorticoid receptor nucleus translocation
J Jiao, D Xu, Y Kong, Y Cao, L Wang, Y Hong, L Li, C Gao, J Liu, G Zhang, ...
Science bulletin 69 (24), 3826-3831, 2024
22024
Artificial meshed vessel-induced dimensional breaking growth of human brain organoids and multiregional assembloids
L Xu, H Ding, S Wu, N Xiong, Y Hong, W Zhu, X Chen, X Han, M Tao, ...
ACS nano 18 (38), 26201-26214, 2024
22024
Research progress of brain organoids in regenerative medicine
H Yuan, LIU Yan
Synthetic Biology Journal, 1, 2024
12024
Deficiency of FABP7 Triggers Premature Neural Differentiation in Idiopathic Normocephalic Autism Organoids
X Han, Y He, Y Wang, W Hu, C Chu, L Huang, Y Hong, L Han, X Zhang, ...
Advanced Science 12 (2), 2406849, 2025
2025
Single‐Cell Transcriptome Landscape and Cell Fate Decoding in Human Brain Organoids after Transplantation (Adv. Sci. 28/2024)
SB Xu, XR Li, P Fan, X Li, Y Hong, X Han, S Wu, C Chu, Y Chen, M Xu, ...
Advanced Science 11 (28), 2470167, 2024
2024
Human Brain Organoids Model Abnormal Prenatal Neural Development Induced by Thermal Stimulation
L Xu, Y Zhang, X Chen, Y Hong, X Zhang, H Hu, X Han, X Zou, M Xu, ...
Cell Proliferation, e13777, 2024
2024
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