| Genetic variants associated with cancer therapy–induced cardiomyopathy P Garcia-Pavia, Y Kim, MA Restrepo-Cordoba, IG Lunde, H Wakimoto, ... Circulation 140 (1), 31-41, 2019 | 290 | 2019 |
| Myosin sequestration regulates sarcomere function, cardiomyocyte energetics, and metabolism, informing the pathogenesis of hypertrophic cardiomyopathy CN Toepfer, AC Garfinkel, G Venturini, H Wakimoto, G Repetti, L Alamo, ... Circulation 141 (10), 828-842, 2020 | 276 | 2020 |
| Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin CN Toepfer, H Wakimoto, AC Garfinkel, B McDonough, D Liao, J Jiang, ... Science translational medicine 11 (476), eaat1199, 2019 | 202 | 2019 |
| SarcTrack: an adaptable software tool for efficient large-scale analysis of sarcomere function in hiPSC-cardiomyocytes CN Toepfer, A Sharma, M Cicconet, AC Garfinkel, M Mücke, M Neyazi, ... Circulation research 124 (8), 1172-1183, 2019 | 114 | 2019 |
| Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease C Toepfer, V Caorsi, T Kampourakis, MB Sikkel, T West, JC Leung, ... Biophysical Journal 104 (2), 309a-310a, 2013 | 89 | 2013 |
| Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor Y Guo, BD Jardin, P Zhou, I Sethi, BN Akerberg, CN Toepfer, Y Ai, Y Li, ... Nature communications 9 (1), 3837, 2018 | 86 | 2018 |
| CRISPR/Cas9‐mediated fluorescent tagging of endogenous proteins in human pluripotent stem cells A Sharma, CN Toepfer, T Ward, L Wasson, R Agarwal, DA Conner, JH Hu, ... Current protocols in human genetics 96 (1), 21.11. 1-21.11. 20, 2018 | 85 | 2018 |
| Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics M Schmid, CN Toepfer Biology open 10 (2), bio057646, 2021 | 73 | 2021 |
| Novel therapies for prevention and early treatment of cardiomyopathies: now and in the future GG Repetti, CN Toepfer, JG Seidman, CE Seidman Circulation research 124 (11), 1536-1550, 2019 | 69 | 2019 |
| GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm A Sharma, LK Wasson, JAL Willcox, SU Morton, JM Gorham, ... Elife 9, e53278, 2020 | 53 | 2020 |
| CalTrack: high-throughput automated calcium transient analysis in cardiomyocytes Y Psaras, F Margara, M Cicconet, AJ Sparrow, GG Repetti, M Schmid, ... Circulation research 129 (2), 326-341, 2021 | 52 | 2021 |
| Differentiation and contractile analysis of GFP‐sarcomere reporter hiPSC‐cardiomyocytes A Sharma, CN Toepfer, M Schmid, AC Garfinkel, CE Seidman Current protocols in human genetics 96 (1), 21.12. 1-21.12. 12, 2018 | 45 | 2018 |
| Filamin C cardiomyopathy variants cause protein and lysosome accumulation R Agarwal, JA Paulo, CN Toepfer, JK Ewoldt, S Sundaram, A Chopra, ... Circulation research 129 (7), 751-766, 2021 | 42 | 2021 |
| Non-linear optical microscopy sheds light on cardiovascular disease V Caorsi, C Toepfer, MB Sikkel, AR Lyon, K MacLeod, MA Ferenczi PLoS One 8 (2), e56136, 2013 | 35 | 2013 |
| Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients CJ Pua, N Tham, CWL Chin, R Walsh, CC Khor, CN Toepfer, GG Repetti, ... Circulation: Genomic and Precision Medicine 13 (5), 424-434, 2020 | 31 | 2020 |
| Power output of skinned skeletal muscle fibres from the cheetah (Acinonyx jubatus) TG West, CN Toepfer, RC Woledge, NA Curtin, A Rowlerson, ... Journal of Experimental Biology 216 (15), 2974-2982, 2013 | 30 | 2013 |
| Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization K Zhang, PE Cloonan, S Sundaram, F Liu, SL Das, JK Ewoldt, JL Bays, ... Science Advances 7 (42), eabh3995, 2021 | 28 | 2021 |
| Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere R Agarwal, H Wakimoto, JA Paulo, Q Zhang, D Reichart, C Toepfer, ... Circulation 146 (22), 1674-1693, 2022 | 26 | 2022 |
| Revisiting Frank–Starling: regulatory light chain phosphorylation alters the rate of force redevelopment (ktr) in a length‐dependent fashion CN Toepfer, TG West, MA Ferenczi The Journal of Physiology 594 (18), 5237-5254, 2016 | 25 | 2016 |
| Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy F Margara, Y Psaras, ZJ Wang, M Schmid, R Doste, AC Garfinkel, ... Scientific reports 12 (1), 22501, 2022 | 21 | 2022 |
Arun SharmaAssistant Professor, Cedars-Sinai Medical CenterVerified email at cshs.org
