| Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints S Koyama, EA Akbay, YY Li, GS Herter-Sprie, KA Buczkowski, ... Nature communications 7 (1), 10501, 2016 | 1545 | 2016 |
| STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T-cell activity in the lung tumor microenvironment S Koyama, EA Akbay, YY Li, AR Aref, F Skoulidis, GS Herter-Sprie, ... Cancer research 76 (5), 999-1008, 2016 | 576 | 2016 |
| Mechanisms and therapeutic implications of hypermutation in gliomas M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ... Nature 580 (7804), 517-523, 2020 | 556 | 2020 |
| Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, KE Lowder, ... Cell 184 (25), 6119-6137. e26, 2021 | 361 | 2021 |
| Drug repositioning for personalized medicine YY Li, SJM Jones Genome medicine 4, 1-14, 2012 | 334 | 2012 |
| Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations YY Li, GTY Chung, VWY Lui, KF To, BBY Ma, C Chow, JKS Woo, KY Yip, ... Nature communications 8 (1), 14121, 2017 | 333 | 2017 |
| LKB1 loss links serine metabolism to DNA methylation and tumorigenesis F Kottakis, BN Nicolay, A Roumane, R Karnik, H Gu, JM Nagle, ... Nature 539 (7629), 390-395, 2016 | 321 | 2016 |
| Genomic analysis of metastatic cutaneous squamous cell carcinoma YY Li, GJ Hanna, AC Laga, RI Haddad, JH Lorch, PS Hammerman Clinical cancer research 21 (6), 1447-1456, 2015 | 307 | 2015 |
| Diminished efficacy of programmed death-(ligand) 1 inhibition in STK11-and KEAP1-mutant lung adenocarcinoma is affected by KRAS mutation status B Ricciuti, KC Arbour, JJ Lin, A Vajdi, N Vokes, L Hong, J Zhang, ... Journal of Thoracic Oncology 17 (3), 399-410, 2022 | 269 | 2022 |
| Stemness-related markers in cancer W Zhao, Y Li, X Zhang Cancer translational medicine 3 (3), 87, 2017 | 232 | 2017 |
| Association of high tumor mutation burden in non–small cell lung cancers with increased immune infiltration and improved clinical outcomes of PD-L1 blockade across PD-L1 … B Ricciuti, X Wang, JV Alessi, H Rizvi, NR Mahadevan, YY Li, A Polio, ... JAMA oncology 8 (8), 1160-1168, 2022 | 231 | 2022 |
| Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors SJM Jones, J Laskin, YY Li, OL Griffith, J An, M Bilenky, YS Butterfield, ... Genome biology 11, 1-12, 2010 | 207 | 2010 |
| Molecular mechanisms of acquired resistance to MET tyrosine kinase inhibitors in patients with MET exon 14–mutant NSCLC G Recondo, M Bahcall, LF Spurr, J Che, B Ricciuti, GC Leonardi, YC Lo, ... Clinical Cancer Research 26 (11), 2615-2625, 2020 | 178 | 2020 |
| Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells AL Stratford, CJ Fry, C Desilets, AH Davies, YY Cho, Y Li, Z Dong, ... Breast Cancer Research 10, 1-12, 2008 | 177 | 2008 |
| Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer GS Herter-Sprie, S Koyama, H Korideck, J Hai, J Deng, YY Li, ... JCI insight 1 (9), 2016 | 165 | 2016 |
| Genomic landscape of human papillomavirus–associated cancers M Rusan, YY Li, PS Hammerman Clinical cancer research 21 (9), 2009-2019, 2015 | 153 | 2015 |
| A computational approach to finding novel targets for existing drugs YY Li, J An, SJM Jones PLoS computational biology 7 (9), e1002139, 2011 | 149 | 2011 |
| Suppression of myeloid cell arginase activity leads to therapeutic response in a NSCLC mouse model by activating anti-tumor immunity JJ Miret, P Kirschmeier, S Koyama, M Zhu, YY Li, Y Naito, M Wu, ... Journal for immunotherapy of cancer 7, 1-12, 2019 | 139 | 2019 |
| Improving the specificity of high-throughput ortholog prediction DL Fulton, YY Li, MR Laird, BGS Horsman, FM Roche, FSL Brinkman BMC bioinformatics 7, 1-16, 2006 | 136 | 2006 |
| cisRED: a database system for genome-scale computational discovery of regulatory elements G Robertson, M Bilenky, K Lin, A He, W Yuen, M Dagpinar, R Varhol, ... Nucleic acids research 34 (suppl_1), D68-D73, 2006 | 136 | 2006 |
