A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR H Torikai, A Reik, PQ Liu, Y Zhou, L Zhang, S Maiti, H Huls, JC Miller, ... Blood, The Journal of the American Society of Hematology 119 (24), 5697-5705, 2012 | 699 | 2012 |
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors H Torikai, A Reik, F Soldner, EH Warren, C Yuen, Y Zhou, DL Crossland, ... Blood, The Journal of the American Society of Hematology 122 (8), 1341-1349, 2013 | 375 | 2013 |
CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo G Tian, AN Courtney, B Jena, A Heczey, D Liu, E Marinova, L Guo, X Xu, ... The Journal of clinical investigation 126 (6), 2341-2355, 2016 | 165 | 2016 |
CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA LJN Cooper, H Torikai US Patent 10,391,126, 2019 | 130 | 2019 |
Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen T Kawase, Y Akatsuka, H Torikai, S Morishima, A Oka, A Tsujimura, ... Blood, The Journal of the American Society of Hematology 110 (3), 1055-1063, 2007 | 126 | 2007 |
Sleeping beauty system to redirect T-cell specificity for human applications SN Maiti, H Huls, H Singh, M Dawson, M Figliola, S Olivares, P Rao, ... Journal of immunotherapy 36 (2), 112-123, 2013 | 118 | 2013 |
Human application of engineered chimeric antigen receptor (CAR) T-cells LJ Cooper, H Torikai, L Zhang, H Helen, F Wang-Johanning, L Hurton, ... US Patent 9,629,877, 2017 | 92 | 2017 |
Translational implications for off-the-shelf immune cells expressing chimeric antigen receptors H Torikai, LJN Cooper Molecular Therapy 24 (7), 1178-1186, 2016 | 83 | 2016 |
A novel HLA-A* 3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human TMSB4Y gene H Torikai, Y Akatsuka, M Miyazaki, EH Warren, T Oba, K Tsujimura, ... The Journal of Immunology 173 (11), 7046-7054, 2004 | 74 | 2004 |
Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA T Kawase, Y Nannya, H Torikai, G Yamamoto, M Onizuka, S Morishima, ... Blood, The Journal of the American Society of Hematology 111 (6), 3286-3294, 2008 | 69 | 2008 |
Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123 … R Thokala, S Olivares, T Mi, S Maiti, D Deniger, H Huls, H Torikai, H Singh, ... PloS one 11 (8), e0159477, 2016 | 68 | 2016 |
HapMap scanning of novel human minor histocompatibility antigens M Kamei, Y Nannya, H Torikai, T Kawase, K Taura, Y Inamoto, ... Blood, The Journal of the American Society of Hematology 113 (21), 5041-5048, 2009 | 67 | 2009 |
Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application H Torikai, T Mi, L Gragert, M Maiers, A Najjar, S Ang, S Maiti, J Dai, ... Scientific reports 6 (1), 21757, 2016 | 49 | 2016 |
The human cathepsin H gene encodes two novel minor histocompatibility antigen epitopes restricted by HLA‐A*3101 and ‐A*3303 H Torikai, Y Akatsuka, M Miyazaki, A Tsujimura, Y Yatabe, T Kawase, ... British journal of haematology 134 (4), 406-416, 2006 | 45 | 2006 |
Redirecting T-cell specificity to EGFR using mRNA to self-limit expression of chimeric antigen receptor HG Caruso, H Torikai, L Zhang, S Maiti, J Dai, KA Do, H Singh, H Huls, ... Journal of immunotherapy 39 (5), 205-217, 2016 | 42 | 2016 |
Histiocytic sarcoma of the spleen: case report of asymptomatic onset of thrombocytopenia and complex imaging features S Kobayashi, F Kimura, Y Hama, K Ogura, H Torikai, A Kobayashi, ... International journal of hematology 87, 83-87, 2008 | 40 | 2008 |
Identification of an HLA‐A24‐restricted cytotoxic T lymphocyte epitope from human papillomavirus type‐16 E6: The combined effects of bortezomib and interferon‐γ on the … S Morishima, Y Akatsuka, A Nawa, E Kondo, T Kiyono, H Torikai, ... International journal of cancer 120 (3), 594-604, 2007 | 37 | 2007 |
The HLA-A* 0201-restricted minor histocompatibility antigen HA-1H peptide can also be presented by another HLA-A2 subtype, A* 0206 H Torikai, Y Akatsuka, H Miyauchi, S Terakura, M Onizuka, K Tsujimura, ... Bone marrow transplantation 40 (2), 165-174, 2007 | 31 | 2007 |
A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells Y Choi, C Yuen, SN Maiti, S Olivares, H Gibbons, H Huls, R Raphael, ... Biomedical microdevices 12, 855-863, 2010 | 29 | 2010 |
Human application of engineered chimeric antigen receptor (car) t-cells LJ Cooper, H Torikai, L Zhang, H Helen, F Wang-Johanning, L Hurton, ... US Patent App. 15/434,595, 2017 | 24 | 2017 |