Infection of bat and human intestinal organoids by SARS-CoV-2 J Zhou, C Li, X Liu, MC Chiu, X Zhao, D Wang, Y Wei, A Lee, AJ Zhang, ... Nature medicine 26 (7), 1077-1083, 2020 | 587 | 2020 |
Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways H Chu, J Zhou, BHY Wong, C Li, JFW Chan, ZS Cheng, D Yang, D Wang, ... The Journal of infectious diseases 213 (6), 904-914, 2016 | 502 | 2016 |
Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for … J Zhou, H Chu, C Li, BHY Wong, ZS Cheng, VKM Poon, T Sun, CCY Lau, ... The Journal of infectious diseases 209 (9), 1331-1342, 2014 | 494 | 2014 |
Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus J Zhou, C Li, G Zhao, H Chu, D Wang, HHN Yan, VKM Poon, L Wen, ... Science advances 3 (11), eaao4966, 2017 | 447 | 2017 |
Differentiated human airway organoids to assess infectivity of emerging influenza virus J Zhou, C Li, N Sachs, MC Chiu, BHY Wong, H Chu, VKM Poon, D Wang, ... Proceedings of the National Academy of Sciences 115 (26), 6822-6827, 2018 | 276 | 2018 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 248 | 2019 |
Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response H Chu, J Zhou, BHY Wong, C Li, ZS Cheng, X Lin, VKM Poon, T Sun, ... Virology 454, 197-205, 2014 | 222 | 2014 |
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RKH Au-Yeung, ... Journal of Biological Chemistry 293 (30), 11709-11726, 2018 | 193 | 2018 |
Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza Z Cheng, J Zhou, KKW To, H Chu, C Li, D Wang, D Yang, S Zheng, K Hao, ... The Journal of infectious diseases 212 (8), 1214-1221, 2015 | 190 | 2015 |
A broad-spectrum virus-and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 H Zhao, KKW To, KH Sze, TTM Yung, M Bian, H Lam, ML Yeung, C Li, ... Nature communications 11 (1), 4252, 2020 | 118 | 2020 |
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies D Zhou, JFW Chan, B Zhou, R Zhou, S Li, S Shan, L Liu, AJ Zhang, ... Cell host & microbe 29 (4), 551-563. e5, 2021 | 110 | 2021 |
Discovery of DNA viruses in wild-caught mosquitoes using small RNA high throughput sequencing M Ma, Y Huang, Z Gong, L Zhuang, C Li, H Yang, Y Tong, W Liu, W Cao PLoS One 6 (9), e24758, 2011 | 88 | 2011 |
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity H Chu, H Shuai, Y Hou, X Zhang, L Wen, X Huang, B Hu, D Yang, ... Science advances 7 (25), eabf8577, 2021 | 79 | 2021 |
Natural transmission of bat-like SARS-CoV-2ΔPRRA variants in COVID-19 patients YC Wong, SY Lau, KKW To, BWY Mok, X Li, P Wang, S Deng, KF Woo, ... Clinical Infectious Diseases: An Official Publication of the Infectious …, 2020 | 68* | 2020 |
Coronaviruses exploit a host cysteine-aspartic protease for replication H Chu, Y Hou, D Yang, L Wen, H Shuai, C Yoon, J Shi, Y Chai, TTT Yuen, ... Nature 609 (7928), 785-792, 2022 | 60 | 2022 |
Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza H Zhao, KKW To, H Chu, Q Ding, X Zhao, C Li, H Shuai, S Yuan, J Zhou, ... Nature communications 9 (1), 2358, 2018 | 60 | 2018 |
Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target C Li, H Chu, X Liu, MC Chiu, X Zhao, D Wang, Y Wei, Y Hou, H Shuai, ... Emerging Microbes & Infections 9 (1), 2663-2672, 2020 | 57 | 2020 |
A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant MC Chiu, C Li, X Liu, Y Yu, J Huang, Z Wan, D Xiao, H Chu, JP Cai, ... Cell discovery 8 (1), 57, 2022 | 56 | 2022 |
Human intestinal organoids recapitulate enteric infections of enterovirus and coronavirus X Zhao, C Li, X Liu, MC Chiu, D Wang, Y Wei, H Chu, JP Cai, IHY Chan, ... Stem Cell Reports 16 (3), 493-504, 2021 | 56 | 2021 |
Human airway and nasal organoids reveal escalating replicative fitness of SARS-CoV-2 emerging variants C Li, J Huang, Y Yu, Z Wan, MC Chiu, X Liu, S Zhang, JP Cai, H Chu, G Li, ... Proceedings of the National Academy of Sciences 120 (17), e2300376120, 2023 | 54 | 2023 |