| Rapid, complete and large‐scale generation of post‐mitotic neurons from the human LUHMES cell line D Scholz, D Pöltl, A Genewsky, M Weng, T Waldmann, S Schildknecht, ... Journal of neurochemistry 119 (5), 957-971, 2011 | 402 | 2011 |
| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 368 | 2017 |
| Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity: implications for mitochondrial oxidative stress and nitrate tolerance P Wenzel, U Hink, M Oelze, S Schuppan, K Schaeuble, S Schildknecht, ... Journal of Biological Chemistry 282 (1), 792-799, 2007 | 193 | 2007 |
| Vascular aging: chronic oxidative stress and impairment of redox signaling—consequences for vascular homeostasis and disease MM Bachschmid, S Schildknecht, R Matsui, R Zee, D Haeussler, ... Annals of medicine 45 (1), 17-36, 2013 | 189 | 2013 |
| Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies S Schildknecht, HR Gerding, C Karreman, M Drescher, HA Lashuel, ... Journal of neurochemistry 125 (4), 491-511, 2013 | 156 | 2013 |
| In Vitro Research Reproducibility: Keeping Up High Standards C Hirsch, S Schildknecht Frontiers in pharmacology 10, 1484, 2019 | 155 | 2019 |
| Toxicity of organic and inorganic mercury species in differentiated human neurons and human astrocytes H Lohren, L Blagojevic, R Fitkau, F Ebert, S Schildknecht, M Leist, ... Journal of Trace Elements in Medicine and Biology 32, 200-208, 2015 | 152 | 2015 |
| Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure A Daiber, M Oelze, M Coldewey, K Kaiser, C Huth, S Schildknecht, ... Biochemical and biophysical research communications 338 (4), 1865-1874, 2005 | 137 | 2005 |
| Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells S Schildknecht, D Pöltl, DM Nagel, F Matt, D Scholz, J Lotharius, ... Toxicology and applied pharmacology 241 (1), 23-35, 2009 | 133 | 2009 |
| Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite S Schildknecht, R Pape, N Müller, M Robotta, A Marquardt, A Bürkle, ... Journal of Biological Chemistry 286 (7), 4991-5002, 2011 | 125 | 2011 |
| A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles L Hoelting, B Scheinhardt, O Bondarenko, S Schildknecht, M Kapitza, ... Archives of toxicology 87, 721-733, 2013 | 123 | 2013 |
| Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+ AK Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, ... Cell death & disease 5 (5), e1222-e1222, 2014 | 119 | 2014 |
| Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system M Bachschmid, S Schildknecht, V Ullrich Biochemical and biophysical research communications 338 (1), 536-542, 2005 | 119 | 2005 |
| Alpha‐Synuclein binds to the inner membrane of mitochondria in an α‐helical conformation M Robotta, HR Gerding, A Vogel, K Hauser, S Schildknecht, C Karreman, ... Chembiochem 15 (17), 2499-2502, 2014 | 111 | 2014 |
| An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition A Terron, A Bal-Price, A Paini, F Monnet-Tschudi, SH Bennekou, ... Archives of toxicology 92, 41-82, 2018 | 108 | 2018 |
| A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ... Archives of toxicology 89, 1599-1618, 2015 | 103 | 2015 |
| Redox regulation: a new challenge for pharmacology D Frein, S Schildknecht, M Bachschmid, V Ullrich Biochemical Pharmacology 70 (6), 811-823, 2005 | 99 | 2005 |
| Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases S Schildknecht, C Karreman, D Pöltl, L Efrémova, C Kullmann, S Gutbier, ... | 98 | 2013 |
| Tipping points and endogenous determinants of nigrostriatal degeneration by MPTP S Schildknecht, DA Di Monte, R Pape, K Tieu, M Leist Trends in Pharmacological Sciences 38 (6), 541-555, 2017 | 89 | 2017 |
| Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure B Zimmer, S Schildknecht, PB Kuegler, V Tanavde, S Kadereit, M Leist Toxicological Sciences 121 (2), 357-367, 2011 | 89 | 2011 |
