Perturb-seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens A Dixit, O Parnas, B Li, J Chen, CP Fulco, L Jerby-Arnon, ND Marjanovic, ... Cell 167 (7), 1853-1866. e17, 2016 | 1597 | 2016 |
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations CP Fulco, J Nasser, TR Jones, G Munson, DT Bergman, V Subramanian, ... Nature Genetics 51 (12), 1664-1669, 2019 | 868 | 2019 |
Systematic mapping of functional enhancer–promoter connections with CRISPR interference CP Fulco, M Munschauer, R Anyoha, G Munson, SR Grossman, EM Perez, ... Science 354 (6313), 769-773, 2016 | 654 | 2016 |
Inherited causes of clonal haematopoiesis in 97,691 whole genomes AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ... Nature 586 (7831), 763-768, 2020 | 591 | 2020 |
Genome-wide enhancer maps link risk variants to disease genes J Nasser, DT Bergman, CP Fulco, P Guckelberger, BR Doughty, ... Nature 593 (7858), 238-243, 2021 | 510 | 2021 |
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ... Nature 548, 343-346, 2017 | 434 | 2017 |
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability M Munschauer, CT Nguyen, K Sirokman, CR Hartigan, L Hogstrom, ... Nature 561 (7721), 132-136, 2018 | 384 | 2018 |
Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis RK Khajuria, M Munschauer, JC Ulirsch, C Fiorini, LS Ludwig, ... Cell 173 (1), 90-103. e19, 2018 | 383 | 2018 |
Cycling cancer persister cells arise from lineages with distinct programs Y Oren, M Tsabar, MS Cuoco, L Amir-Zilberstein, HF Cabanos, JC Hütter, ... Nature 596 (7873), 576-582, 2021 | 351 | 2021 |
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases EM Weeks, JC Ulirsch, NY Cheng, BL Trippe, RS Fine, J Miao, ... Nature Genetics 55 (8), 1267-1276, 2023 | 205 | 2023 |
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ... Nature Genetics, 1-10, 2022 | 119 | 2022 |
Compatibility rules of human enhancer and promoter sequences DT Bergman, TR Jones, V Liu, J Ray, E Jagoda, L Siraj, HY Kang, ... Nature 607 (7917), 176-184, 2022 | 117 | 2022 |
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features JP Ray, CG de Boer, CP Fulco, CA Lareau, M Kanai, JC Ulirsch, ... Nature Communications 11 (1), 1-13, 2020 | 50 | 2020 |
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ... Nature Methods 15, 992-993, 2018 | 38 | 2018 |
HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes JL Marshall, BR Doughty, V Subramanian, P Guckelberger, Q Wang, ... Proceedings of the National Academy of Sciences 117 (52), 33404-33413, 2020 | 29 | 2020 |
Rewriting regulatory DNA to dissect and reprogram gene expression GE Martyn, MT Montgomery, H Jones, K Guo, BR Doughty, J Linder, ... bioRxiv, 2023.12. 20.572268, 2023 | 14 | 2023 |
Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease J Dahlqvist, CP Fulco, JP Ray, T Liechti, CG de Boer, DJ Lieb, ... Human Molecular Genetics 31 (12), 1946-1961, 2022 | 11 | 2022 |
Cohesin-mediated 3D contacts tune enhancer-promoter regulation P Guckelberger, BR Doughty, G Munson, SSP Rao, Y Tan, XS Cai, ... bioRxiv, 2024.07. 12.603288, 2024 | 5 | 2024 |
Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma AR Iyer, A Gurumurthy, R Kodgule, AR Aguilar, T Saari, A Ramzan, ... bioRxiv, 2023.05. 02.538892, 2023 | 2 | 2023 |
SYSTEMATIC SCREENING AND MAPPING OF REGULATORY ELEMENTS IN NON-CODING GENOMIC REGIONS, METHODS, COMPOSITIONS, AND APPLICATIONS THEREOF J Engreitz, ES Lander, C Fulco US Patent App. 16/337,846, 2020 | 2 | 2020 |