Zika virus infection damages the testes in mice J Govero, P Esakky, SM Scheaffer, E Fernandez, A Drury, DJ Platt, ... Nature 540 (7633), 438-442, 2016 | 569 | 2016 |
Chloroquine, an endocytosis blocking agent, inhibits Zika virus infection in different cell models R Delvecchio, LM Higa, P Pezzuto, AL Valadão, PP Garcez, FL Monteiro, ... Viruses 8 (12), 322, 2016 | 348 | 2016 |
Characterization of lethal Zika virus infection in AG129 mice MT Aliota, EA Caine, EC Walker, KE Larkin, E Camacho, JE Osorio PLoS neglected tropical diseases 10 (4), e0004682, 2016 | 348 | 2016 |
Vaccine mediated protection against Zika virus-induced congenital disease JM Richner, BW Jagger, C Shan, CR Fontes, KA Dowd, B Cao, ... Cell 170 (2), 273-283. e12, 2017 | 290 | 2017 |
An immunocompetent mouse model of Zika virus infection MJ Gorman, EA Caine, K Zaitsev, MC Begley, J Weger-Lucarelli, ... Cell host & microbe 23 (5), 672-685. e6, 2018 | 237 | 2018 |
Interferon lambda protects the female reproductive tract against Zika virus infection EA Caine, SM Scheaffer, N Arora, K Zaitsev, MN Artyomov, CB Coyne, ... Nature communications 10 (1), 280, 2019 | 119 | 2019 |
Animal models of Zika virus infection during pregnancy EA Caine, BW Jagger, MS Diamond Viruses 10 (11), 598, 2018 | 71 | 2018 |
Efficacy of a trivalent hand, foot, and mouth disease vaccine against enterovirus 71 and coxsackieviruses A16 and A6 in mice EA Caine, J Fuchs, SC Das, CD Partidos, JE Osorio Viruses 7 (11), 5919-5932, 2015 | 67 | 2015 |
A single mutation in the VP1 of enterovirus 71 is responsible for increased virulence and neurotropism in adult interferon-deficient mice EA Caine, LH Moncla, MD Ronderos, TC Friedrich, JE Osorio Journal of virology 90 (19), 8592-8604, 2016 | 57 | 2016 |
Adaptation of enterovirus 71 to adult interferon deficient mice EA Caine, CD Partidos, JD Santangelo, JE Osorio PloS one 8 (3), e59501, 2013 | 55 | 2013 |
The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation KM Riching, EA Caine, M Urh, DL Daniels Chemical Society Reviews 51 (14), 6210-6221, 2022 | 35 | 2022 |
Targeted protein degradation phenotypic studies using HaloTag CRISPR/Cas9 endogenous tagging coupled with HaloPROTAC3 EA Caine, SD Mahan, RL Johnson, AN Nieman, N Lam, CR Warren, ... Current Protocols in Pharmacology 91 (1), e81, 2020 | 33 | 2020 |
Zika virus causes acute infection and inflammation in the ovary of mice without apparent defects in fertility EA Caine, SM Scheaffer, DE Broughton, V Salazar, J Govero, S Poddar, ... The Journal of Infectious Diseases 220 (12), 1904-1914, 2019 | 24 | 2019 |
In Vivo Imaging with Bioluminescent Enterovirus 71 Allows for Real-Time Visualization of Tissue Tropism and Viral Spread EA Caine, JE Osorio Journal of Virology 91 (5), 10.1128/jvi. 01759-16, 2017 | 22 | 2017 |
Correction: characterization of lethal Zika virus infection in AG129 mice MT Aliota, EA Caine, EC Walker, KE Larkin, E Camacho, JE Osorio Plos Neglected Tropical Diseases 10 (5), e0004750, 2016 | 14 | 2016 |
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines G Nishiguchi, LG Mascibroda, SM Young, EA Caine, S Abdelhamed, ... Nature Communications 15 (1), 482, 2024 | 11 | 2024 |
Structure–Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α G Nishiguchi, EA Caine, K McGowan, Z Shi, A Aggarwal, A Mayasundari, ... ACS Medicinal Chemistry Letters 15 (10), 1692-1698, 2024 | 4 | 2024 |
Zika virus exhibits tropism to the ovary and increases follicular apoptosis in a mouse model DE Broughton, S Scheaffer, ME Skaznik-Wikiel, J Halabi, J Govero, ... Fertility and Sterility 108 (3), e35, 2017 | 3 | 2017 |
Leveraging Dual-Ligase Recruitment to Enhance Protein Degradation via a Heterotrivalent Proteolysis Targeting Chimera AG Bond, M Muñoz i Ordoño, CM Bisbach, C Craigon, N Makukhin, ... Journal of the American Chemical Society, 2024 | 1 | 2024 |
Rationally Designed Potent and Selective CK1α Degraders Exert Antiproliferative Activity Against a Broad Range of Human Cancer Cell Lines Z Rankovic, G Nishiguchi, S Abdelhamed, S Young, E Caine, ... | 1 | 2023 |