RNF12 Activates Xist and Is Essential for X Chromosome Inactivation TS Barakat, N Gunhanlar, C Gontan Pardo, EM Achame, M Ghazvini, ... PLoS genetics 7 (1), e1002001, 2011 | 180 | 2011 |
Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI R Boers, J Boers, B de Hoon, C Kockx, Z Ozgur, A Molijn, W van IJcken, ... Genome research 28 (1), 88-99, 2018 | 79 | 2018 |
SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females FC Radio, K Pang, A Ciolfi, MA Levy, A Hernández-García, L Pedace, ... The American Journal of Human Genetics 108 (3), 502-516, 2021 | 74 | 2021 |
Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation M Zhao, CH Kiernan, CJ Stairiker, JL Hope, LG Leon, M van Meurs, ... PLoS pathogens 16 (6), e1008555, 2020 | 55 | 2020 |
CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells W Soochit, F Sleutels, G Stik, M Bartkuhn, S Basu, SC Hernandez, ... Nature cell biology 23 (8), 881-893, 2021 | 50 | 2021 |
Perturbed maintenance of transcriptional repression on the inactive X-chromosome in the mouse brain after Xist deletion RL Adrianse, K Smith, T Gatbonton-Schwager, SP Sripathy, U Lao, ... Epigenetics & chromatin 11, 1-13, 2018 | 47 | 2018 |
Gestational jet lag predisposes to later-life skeletal and cardiac disease I Chaves, B van der Eerden, R Boers, J Boers, AA Streng, Y Ridwan, ... Chronobiology international 36 (5), 657-671, 2019 | 25 | 2019 |
Genome-wide aberrant methylation in primary metastatic UM and their matched metastases KN Smit, R Boers, J Vaarwater, J Boers, T Brands, H Mensink, RM Verdijk, ... Scientific Reports 12 (1), 42, 2022 | 21 | 2022 |
High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments T Deger, RG Boers, V de Weerd, L Angus, MMJ van der Put, JB Boers, ... Clinical Epigenetics 13, 1-17, 2021 | 19 | 2021 |
Differentially methylated regions in desmoid-type fibromatosis: a comparison between CTNNB1 S45F and T41A tumors MJM Timbergen, R Boers, ALM Vriends, J Boers, WFJ van IJcken, ... Frontiers in Oncology 10, 565031, 2020 | 16 | 2020 |
XIST dampens X chromosome activity in a SPEN-dependent manner during early human development C Alfeghaly, G Castel, E Cazottes, M Moscatelli, E Moinard, M Casanova, ... Nature Structural & Molecular Biology, 1-12, 2024 | 11 | 2024 |
Genome wide DNA methylation analysis of alveolar capillary dysplasia lung tissue reveals aberrant methylation of genes involved in development including the FOXF1 locus E Slot, R Boers, J Boers, WFJ van IJcken, D Tibboel, J Gribnau, R Rottier, ... Clinical Epigenetics 13, 1-12, 2021 | 11 | 2021 |
Retrospective analysis of enhancer activity and transcriptome history R Boers, J Boers, B Tan, ME van Leeuwen, E Wassenaar, EG Sanchez, ... Nature Biotechnology 41 (11), 1582-1592, 2023 | 10 | 2023 |
Cystic renal-epithelial derived induced pluripotent stem cells from polycystic kidney disease patients AT Kenter, E Rentmeester, J Riet, R Boers, J Boers, M Ghazvini, VJ Xavier, ... Stem Cells Translational Medicine 9 (4), 478-490, 2020 | 10 | 2020 |
Genetic and epigenetic determinants of reactivation of Mecp2 and the inactive X chromosome in neural stem cells H Mira-Bontenbal, B Tan, C Gontan, S Goossens, RG Boers, JB Boers, ... Stem Cell Reports 17 (3), 693-706, 2022 | 9 | 2022 |
Kidney organoids are capable of forming tumors, but not teratomas AS Shankar, Z Du, H Tejeda Mora, R Boers, W Cao, TPP van den Bosch, ... Stem Cells 40 (6), 577-591, 2022 | 7 | 2022 |
Characterization of histone modifications associated with inactive X-chromosome in trophoblast stem cells, eXtra-embryonic endoderm cells and in in vitro derived … C Dupont, C Maduro, H Den Braanker, R Boers, D Kurek, J Gribnau PloS one 11 (12), e0167154, 2016 | 7 | 2016 |
Hypermethylation of DNA methylation markers in non-cirrhotic hepatocellular carcinoma S Fu, T Deger, RG Boers, JB Boers, M Doukas, J Gribnau, SM Wilting, ... Cancers 15 (19), 4784, 2023 | 4 | 2023 |
Genome-wide analysis toward the epigenetic aetiology of myelodysplastic syndrome disease progression and pharmacoepigenomic basis of hypomethylating agents drug treatment response S Siamoglou, R Boers, M Koromina, J Boers, A Tsironi, T Chatzilygeroudi, ... Human Genomics 17 (1), 37, 2023 | 4 | 2023 |
Liquid Biopsies for Colorectal Cancer and Advanced Adenoma Screening and Surveillance: What to Measure? EL Eikenboom, SM Wilting, T Deger, MI Srebniak, ... Cancers 15 (18), 4607, 2023 | 3 | 2023 |