| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3634 | 2010 |
| Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation UM Zanger, M Turpeinen, K Klein, M Schwab Analytical and bioanalytical chemistry 392, 1093-1108, 2008 | 763 | 2008 |
| Inhibition and induction of human cytochrome P450 enzymes: current status O Pelkonen, M Turpeinen, J Hakkola, P Honkakoski, J Hukkanen, ... Archives of toxicology 82, 667-715, 2008 | 732 | 2008 |
| Inhibition and induction of CYP enzymes in humans: an update J Hakkola, J Hukkanen, M Turpeinen, O Pelkonen Archives of Toxicology 94 (11), 3671-3722, 2020 | 331 | 2020 |
| Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells S Antherieu, C Chesne, R Li, S Camus, A Lahoz, L Picazo, M Turpeinen, ... Drug Metabolism and Disposition 38 (3), 516-525, 2010 | 295 | 2010 |
| Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation M Turpeinen, A Tolonen, J Uusitalo, J Jalonen, O Pelkonen, K Laine Clinical Pharmacology & Therapeutics 77 (6), 553-559, 2005 | 178 | 2005 |
| Prediction of Drug Metabolism and Interactions on the Basis of in vitro Investigations O Pelkonen, M Turpeinen, J Uusitalo, A Rautio, H Raunio Basic & clinical pharmacology & toxicology 96 (3), 167-175, 2005 | 173 | 2005 |
| Liquid chromatography–mass spectrometry in in vitro drug metabolite screening A Tolonen, M Turpeinen, O Pelkonen Drug discovery today 14 (3-4), 120-133, 2009 | 168 | 2009 |
| The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico M Turpeinen, H Raunio, O Pelkonen Current drug metabolism 7 (7), 705-714, 2006 | 168 | 2006 |
| Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay M Turpeinen, U Jouko, J Jorma, P Olavi European journal of pharmaceutical sciences 24 (1), 123-132, 2005 | 167 | 2005 |
| Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation AM Gomes, S Winter, K Klein, M Turpeinen, E Schaeffeler, M Schwab, ... Pharmacogenomics 10 (4), 579-599, 2009 | 153 | 2009 |
| Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro M Turpeinen, R Nieminen, T Juntunen, P Taavitsainen, H Raunio, ... Drug metabolism and disposition 32 (6), 626-631, 2004 | 137 | 2004 |
| CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with … M Hidestrand, M Oscarson, JS Salonen, L Nyman, O Pelkonen, ... Drug Metabolism and Disposition 29 (11), 1480-1484, 2001 | 132 | 2001 |
| Functional expression, inhibition and induction of CYP enzymes in HepaRG cells M Turpeinen, A Tolonen, C Chesne, A Guillouzo, J Uusitalo, O Pelkonen Toxicology in Vitro 23 (4), 748-753, 2009 | 130 | 2009 |
| In vitro–in vivo extrapolation of hepatic clearance: Biological tools, scaling factors, model assumptions and correct concentrations O Pelkonen, M Turpeinen Xenobiotica 37 (10-11), 1066-1089, 2007 | 130 | 2007 |
| Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative study in vitro M Turpeinen, C Ghiciuc, M Opritoui, L Tursas, O Pelkonen, M Pasanen Xenobiotica 37 (12), 1367-1377, 2007 | 129 | 2007 |
| Vildagliptin significantly increases the risk of bullous pemphigoid: a Finnish nationwide registry study O Varpuluoma, AK Försti, J Jokelainen, M Turpeinen, M Timonen, ... Elsevier, 2018 | 125 | 2018 |
| Cytochrome P450 2B6: function, genetics, and clinical relevance M Turpeinen, UM Zanger Drug Metabolism and Drug Interactions 27 (4), 185-197, 2012 | 122 | 2012 |
| In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with … A Tolonen, A Petsalo, M Turpeinen, J Uusitalo, O Pelkonen Journal of mass spectrometry 42 (7), 960-966, 2007 | 117 | 2007 |
| The prevalence of medication-related adverse events in inpatients—a systematic review and meta-analysis O Laatikainen, J Miettunen, S Sneck, H Lehtiniemi, O Tenhunen, ... European Journal of Clinical Pharmacology 73, 1539-1549, 2017 | 104 | 2017 |
