| Efficacy and safety of recombinant human activated protein C for severe sepsis GR Bernard, JL Vincent, PF Laterre, SP LaRosa, JF Dhainaut, ... New England journal of medicine 344 (10), 699-709, 2001 | 7569 | 2001 |
| Hydrocortisone therapy for patients with septic shock CL Sprung, D Annane, D Keh, R Moreno, M Singer, K Freivogel, ... New England Journal of Medicine 358 (2), 111-124, 2008 | 2756 | 2008 |
| Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial E Abraham, K Reinhart, S Opal, I Demeyer, C Doig, AL Rodriguez, ... Jama 290 (2), 238-247, 2003 | 1279 | 2003 |
| Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death E Abraham, PF Laterre, R Garg, H Levy, D Talwar, BL Trzaskoma, ... New England Journal of Medicine 353 (13), 1332-1341, 2005 | 1148 | 2005 |
| Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological study MLNG Malbrain, D Chiumello, P Pelosi, D Bihari, R Innes, VM Ranieri, ... Critical care medicine 33 (2), 315-322, 2005 | 1124 | 2005 |
| Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial SM Opal, PF Laterre, B Francois, SP LaRosa, DC Angus, JP Mira, ... Jama 309 (11), 1154-1162, 2013 | 927 | 2013 |
| The SOFA score—development, utility and challenges of accurate assessment in clinical trials S Lambden, PF Laterre, MM Levy, B Francois Critical Care 23, 1-9, 2019 | 920 | 2019 |
| Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study MLNG Malbrain, D Chiumello, P Pelosi, A Wilmer, N Brienza, V Malcangi, ... Intensive care medicine 30, 822-829, 2004 | 812 | 2004 |
| Early antibiotic treatment for severe acute necrotizing pancreatitis: a randomized, double-blind, placebo-controlled study EP Dellinger, JM Tellado, NE Soto, SW Ashley, PS Barie, T Dugernier, ... Annals of surgery 245 (5), 674-683, 2007 | 594 | 2007 |
| Effect of recombinant surfactant protein C–based surfactant on the acute respiratory distress syndrome RG Spragg, JF Lewis, HD Walmrath, J Johannigman, G Bellingan, ... New England Journal of Medicine 351 (9), 884-892, 2004 | 592 | 2004 |
| p55 tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock: A randomized controlled multicenter trial E Abraham, MP Glauser, T Butler, J Garbino, D Gelmont, PF Laterre, ... Jama 277 (19), 1531-1538, 1997 | 504 | 1997 |
| Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock FS Taccone, PF Laterre, T Dugernier, H Spapen, I Delattre, X Wittebole, ... Critical care 14, 1-9, 2010 | 476 | 2010 |
| Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569] GT Kinasewitz, SB Yan, B Basson, P Comp, JA Russell, A Cariou, SL Um, ... Critical care 8, 1-9, 2004 | 461 | 2004 |
| Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III … E Abraham, PF Laterre, J Garbino, S Pingleton, T Butler, T Dugernier, ... Critical care medicine 29 (3), 503-510, 2001 | 398 | 2001 |
| A pilot-controlled study of a polymyxin B-immobilized hemoperfusion cartridge in patients with severe sepsis secondary to intra-abdominal infection JL Vincent, PF Laterre, J Cohen, H Burchardi, H Bruining, FA Lerma, ... Shock 23 (5), 400-405, 2005 | 384 | 2005 |
| Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis EW Ely, PF Laterre, DC Angus, JD Helterbrand, H Levy, JF Dhainaut, ... Critical care medicine 31 (1), 12-19, 2003 | 366 | 2003 |
| Liver function abnormalities, clinical profile, and outcome in acute decompensated heart failure M Nikolaou, J Parissis, MB Yilmaz, MF Seronde, M Kivikko, S Laribi, ... European heart journal 34 (10), 742-749, 2013 | 354 | 2013 |
| Adrenal function in sepsis: the retrospective Corticus cohort study D Lipiner-Friedman, CL Sprung, PF Laterre, Y Weiss, SV Goodman, ... Critical care medicine 35 (4), 1012-1018, 2007 | 300 | 2007 |
| SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule A Werion, L Belkhir, M Perrot, G Schmit, S Aydin, Z Chen, A Penaloza, ... Kidney international 98 (5), 1296-1307, 2020 | 284 | 2020 |
| Neurally adjusted ventilatory assist improves patient–ventilator interaction L Piquilloud, L Vignaux, E Bialais, J Roeseler, T Sottiaux, PF Laterre, ... Intensive care medicine 37, 263-271, 2011 | 279 | 2011 |
