von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends PJ Lenting, OD Christophe, CV Denis Blood, The Journal of the American Society of Hematology 125 (13), 2019-2028, 2015 | 515 | 2015 |
Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant J McIntosh, PJ Lenting, C Rosales, D Lee, S Rabbanian, D Raj, N Patel, ... Blood, The Journal of the American Society of Hematology 121 (17), 3335-3344, 2013 | 314 | 2013 |
von Willebrand factor: the old, the new and the unknown PJ Lenting, C Casari, OD Christophe, CV Denis Journal of thrombosis and haemostasis 10 (12), 2428-2437, 2012 | 309 | 2012 |
Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII? PJ Lenting, CV Denis, OD Christophe Blood, The Journal of the American Society of Hematology 130 (23), 2463-2468, 2017 | 290 | 2017 |
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration A Meliani, F Boisgerault, R Hardet, S Marmier, F Collaud, G Ronzitti, ... Nature communications 9 (1), 4098, 2018 | 242 | 2018 |
P-selectin glycoprotein ligand 1 and β2-integrins cooperate in the adhesion of leukocytes to von Willebrand factor R Pendu, V Terraube, OD Christophe, CG Gahmberg, PG de Groot, ... Blood 108 (12), 3746-3752, 2006 | 224 | 2006 |
A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytes S Dasgupta, AM Navarrete, J Bayry, S Delignat, B Wootla, S André, ... Proceedings of the National Academy of Sciences 104 (21), 8965-8970, 2007 | 146 | 2007 |
Macrophage LRP1 contributes to the clearance of von Willebrand factor G Rastegarlari, JN Pegon, C Casari, S Odouard, AM Navarrete, ... Blood, The Journal of the American Society of Hematology 119 (9), 2126-2134, 2012 | 144 | 2012 |
Effects and interferences of emicizumab, a humanised bispecific antibody mimicking activated factor VIII cofactor function, on coagulation assays JI Adamkewicz, DC Chen, I Paz-Priel Thrombosis and haemostasis 119 (07), 1084-1093, 2019 | 139 | 2019 |
Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors A Meliani, F Boisgerault, Z Fitzpatrick, S Marmier, C Leborgne, F Collaud, ... Blood advances 1 (23), 2019-2031, 2017 | 119 | 2017 |
Clearance of von Willebrand factor C Casari, PJ Lenting, N Wohner, OD Christophe, CV Denis Journal of Thrombosis and Haemostasis 11, 202-211, 2013 | 118 | 2013 |
Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5 JN Pegon, M Kurdi, C Casari, S Odouard, CV Denis, OD Christophe, ... Haematologica 97 (12), 1855, 2012 | 116 | 2012 |
Localization of von Willebrand factor binding domains to endothelial extracellular matrix and to type VI collagen. C Denis, D Baruch, CM Kielty, N Ajzenberg, O Christophe, D Meyer Arteriosclerosis and Thrombosis: A Journal of Vascular Biology 13 (3), 398-406, 1993 | 108 | 1993 |
Characterization of the interaction between von Willebrand factor and osteoprotegerin S Shahbazi, PJ Lenting, C Fribourg, V Terraube, CV Denis, ... Journal of Thrombosis and Haemostasis 5 (9), 1956-1962, 2007 | 105 | 2007 |
Identification of galectin-1 and galectin-3 as novel partners for von Willebrand factor N Saint-Lu, BD Oortwijn, JN Pegon, S Odouard, OD Christophe, ... Arteriosclerosis, thrombosis, and vascular biology 32 (4), 894-901, 2012 | 102 | 2012 |
Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia C Casari, V Du, YP Wu, A Kauskot, PG de Groot, OD Christophe, ... Blood, The Journal of the American Society of Hematology 122 (16), 2893-2902, 2013 | 101 | 2013 |
Altered thrombus formation in von Willebrand factor–deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa I Marx, OD Christophe, PJ Lenting, A Rupin, MO Vallez, TJ Verbeuren, ... Blood, The Journal of the American Society of Hematology 112 (3), 603-609, 2008 | 100 | 2008 |
Laboratory monitoring in emicizumab-treated persons with hemophilia A J Müller, I Pekrul, B Pötzsch, B Berning, J Oldenburg, M Spannagl Thrombosis and Haemostasis 119 (09), 1384-1393, 2019 | 97 | 2019 |
Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates MK Chuah, I Petrus, P De Bleser, C Le Guiner, G Gernoux, O Adjali, ... Molecular Therapy 22 (9), 1605-1613, 2014 | 90 | 2014 |
The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status J Rayes, LT Roumenina, JD Dimitrov, Y Repessé, M Ing, O Christophe, ... Blood, The Journal of the American Society of Hematology 123 (1), 121-125, 2014 | 88 | 2014 |