TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops J Zhang, XJ Tian, H Zhang, Y Teng, R Li, F Bai, S Elankumaran, J Xing Science signaling 7 (345), ra91-ra91, 2014 | 519 | 2014 |
Genomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes R Xue, LU Chen, C Zhang, M Fujita, R Li, SM Yan, CK Ong, X Liao, Q Gao, ... Cancer cell 35 (6), 932-947. e8, 2019 | 235 | 2019 |
Variable intra-tumor genomic heterogeneity of multiple lesions in patients with hepatocellular carcinoma R Xue, R Li, H Guo, L Guo, Z Su, X Ni, L Qi, T Zhang, Q Li, Z Zhang, ... Gastroenterology 150 (4), 998-1008, 2016 | 218 | 2016 |
Macroscopic somatic clonal expansion in morphologically normal human urothelium R Li, Y Du, Z Chen, D Xu, T Lin, S Jin, G Wang, Z Liu, M Lu, X Chen, T Xu, ... Science 370 (6512), 82-89, 2020 | 160 | 2020 |
Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma S Jin, R Li, MY Chen, C Yu, LQ Tang, YM Liu, JP Li, YN Liu, YL Luo, ... Cell research 30 (11), 950-965, 2020 | 158 | 2020 |
A body map of somatic mutagenesis in morphologically normal human tissues R Li, L Di, J Li, W Fan, Y Liu, W Guo, W Liu, L Liu, Q Li, L Chen, Y Chen, ... Nature 597 (7876), 398–403, 2021 | 157 | 2021 |
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies D Reichart, EL Lindberg, H Maatz, AMA Miranda, A Viveiros, N Shvetsov, ... Science 377 (6606), eabo1984, 2022 | 144 | 2022 |
Genomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole-exome sequencing XX Chen, Q Zhong, Y Liu, SM Yan, ZH Chen, SZ Jin, TL Xia, RY Li, ... Nature communications 8 (1), 524, 2017 | 130 | 2017 |
Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch K Fujimaki, R Li, H Chen, K Della Croce, HH Zhang, J Xing, F Bai, G Yao Proceedings of the National Academy of Sciences 116 (45), 22624-22634, 2019 | 116 | 2019 |
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer R Li, JR Ferdinand, KW Loudon, GS Bowyer, S Laidlaw, F Muyas, ... Cancer Cell 40 (12), 1583-1599. e10, 2022 | 109 | 2022 |
Inferring the evolution and progression of small-cell lung cancer by single-cell sequencing of circulating tumor cells Z Su, Z Wang, X Ni, J Duan, Y Gao, M Zhuo, R Li, J Zhao, Q Ma, H Bai, ... Clinical Cancer Research 25 (16), 5049-5060, 2019 | 85 | 2019 |
Genomic characterisation of pulmonary subsolid nodules: mutational landscape and radiological features Y Li, X Li, H Li, Y Zhao, Z Liu, K Sun, X Zhu, Q Qi, B An, D Shen, R Li, ... European Respiratory Journal 55 (2), 2020 | 64 | 2020 |
Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma X Liu, S Jin, S Hu, R Li, H Pan, Y Liu, P Lai, D Xu, J Sun, Z Liu, Y Gao, ... Nature communications 13 (1), 1158, 2022 | 58 | 2022 |
Early metastasis detected in patients with multifocal pulmonary ground-glass opacities (GGOs) R Li, X Li, R Xue, F Yang, S Wang, Y Li, D Shen, K Sun, K Chen, W Weng, ... Thorax 73 (3), 290-292, 2018 | 57 | 2018 |
Integrative genomic study of Chinese clear cell renal cell carcinoma reveals features associated with thrombus XM Wang, Y Lu, YM Song, J Dong, RY Li, GL Wang, X Wang, SD Zhang, ... Nature communications 11 (1), 739, 2020 | 54 | 2020 |
De novo detection of somatic mutations in high-throughput single-cell profiling data sets F Muyas, CM Sauer, JE Valle-Inclán, R Li, R Rahbari, TJ Mitchell, ... Nature biotechnology 42 (5), 758-767, 2024 | 46 | 2024 |
Functional built-in template directed siliceous fluorescent supramolecular vesicles as diagnostics J Li, K Liu, H Chen, R Li, M Drechsler, F Bai, J Huang, BZ Tang, Y Yan ACS Applied Materials & Interfaces 9 (26), 21706-21714, 2017 | 40 | 2017 |
Single cell sequencing: technique, application, and future development R Xue, R Li, F Bai Science Bulletin 60 (1), 33-42, 2015 | 32 | 2015 |
Spatial clustering and common regulatory elements correlate with coordinated gene expression J Zhang, H Chen, R Li, DA Taft, G Yao, F Bai, J Xing PLOS Computational Biology, 2019 | 29 | 2019 |
Mutagenic factors and complex clonal relationship of multifocal urothelial cell carcinoma Y Du, R Li, Z Chen, X Wang, T Xu, F Bai European urology 71 (5), 841-843, 2017 | 25 | 2017 |