Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition N Jacque, AM Ronchetti, C Larrue, G Meunier, R Birsen, L Willems, ... Blood, The Journal of the American Society of Hematology 126 (11), 1346-1356, 2015 | 402 | 2015 |
Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia L Willems, N Jacque, A Jacquel, N Neveux, T Trovati Maciel, M Lambert, ... Blood, The Journal of the American Society of Hematology 122 (20), 3521-3532, 2013 | 344 | 2013 |
An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia M Dussiot, TT Maciel, A Fricot, C Chartier, O Negre, J Veiga, D Grapton, ... Nature medicine 20 (4), 398-407, 2014 | 333 | 2014 |
The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation AS Green, N Chapuis, T Trovati Maciel, L Willems, M Lambert, C Arnoult, ... Blood, The Journal of the American Society of Hematology 116 (20), 4262-4273, 2010 | 250 | 2010 |
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors L Berthelot, C Papista, TT Maciel, M Biarnes-Pelicot, E Tissandie, ... Journal of Experimental Medicine 209 (4), 793-806, 2012 | 224 | 2012 |
The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia L Willems, N Chapuis, A Puissant, TT Maciel, AS Green, N Jacque, ... Leukemia 26 (6), 1195-1202, 2012 | 188 | 2012 |
Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis E Trias, S Ibarburu, R Barreto-Núñez, J Babdor, TT Maciel, M Guillo, ... Journal of neuroinflammation 13, 1-12, 2016 | 187 | 2016 |
HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia JB Arlet, JA Ribeil, F Guillem, O Negre, A Hazoume, G Marcion, ... Nature 514 (7521), 242-246, 2014 | 162 | 2014 |
High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells L Poulain, P Sujobert, F Zylbersztejn, S Barreau, L Stuani, M Lambert, ... Leukemia 31 (11), 2326-2335, 2017 | 145 | 2017 |
Pathologic calcification of adult vascular smooth muscle cells differs on their crest or mesodermal embryonic origin M Leroux‐Berger, I Queguiner, TT Maciel, A Ho, F Relaix, H Kempf Journal of Bone and Mineral Research 26 (7), 1543-1553, 2011 | 133 | 2011 |
The role of mast cells in cancers TT Maciel, IC Moura, O Hermine F1000prime reports 7, 2015 | 127 | 2015 |
Lessons to learn from low-dose cyclosporin-A: a new approach for unexpected clinical applications C Flores, G Fouquet, IC Moura, TT Maciel, O Hermine Frontiers in immunology 10, 588, 2019 | 91 | 2019 |
Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia AS Green, TT Maciel, MA Hospital, C Yin, F Mazed, EC Townsend, ... Science advances 1 (8), e1500221, 2015 | 91 | 2015 |
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia S Coulon, M Dussiot, D Grapton, TT Maciel, PHM Wang, C Callens, ... Nature medicine 17 (11), 1456-1465, 2011 | 81 | 2011 |
Erdheim-Chester disease: a concise review M Papo, JF Emile, TT Maciel, P Bay, A Baber, O Hermine, Z Amoura, ... Current Rheumatology Reports 21, 1-9, 2019 | 69 | 2019 |
Gremlin promotes vascular smooth muscle cell proliferation and migration TT Maciel, RS Melo, N Schor, AH Campos Journal of molecular and cellular cardiology 44 (2), 370-379, 2008 | 64 | 2008 |
Innate immune cells, major protagonists of sickle cell disease pathophysiology S Allali, TT Maciel, O Hermine, M de Montalembert Haematologica 105 (2), 273, 2020 | 58 | 2020 |
Hospital MA, Yin C, Mazed F, Townsend EC, et al AS Green, TT Maciel Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3 …, 2015 | 54 | 2015 |
Endostatin expression in the murine model of ischaemia/reperfusion‐induced acute renal failure MH Bellini, EL Coutinho, TC Filgueiras, TT Maciel, N Schor Nephrology 12 (5), 459-465, 2007 | 49 | 2007 |
A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease JG McArthur, N Svenstrup, C Chen, A Fricot, C Carvalho, J Nguyen, ... Haematologica 105 (3), 623, 2019 | 48 | 2019 |