| Biological role and therapeutic potential of IDH mutations in cancer MS Waitkus, BH Diplas, H Yan Cancer cell 34 (2), 186-195, 2018 | 329 | 2018 |
| Isocitrate dehydrogenase mutations in gliomas MS Waitkus, BH Diplas, H Yan Neuro-oncology 18 (1), 16-26, 2015 | 324 | 2015 |
| The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma BH Diplas, X He, JA Brosnan-Cashman, H Liu, LH Chen, Z Wang, ... Nature communications 9 (1), 2087, 2018 | 165 | 2018 |
| The integrated genomic and epigenomic landscape of brainstem glioma LH Chen, C Pan, BH Diplas, C Xu, LJ Hansen, Y Wu, X Chen, Y Geng, ... Nature communications 11 (1), 3077, 2020 | 70 | 2020 |
| Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation R Yang, LH Chen, LJ Hansen, AB Carpenter, CJ Moure, H Liu, CJ Pirozzi, ... Cancer research 77 (22), 6097-6108, 2017 | 57 | 2017 |
| Mutant IDH1 disrupts the mouse subventricular zone and alters brain tumor progression CJ Pirozzi, AB Carpenter, MS Waitkus, CY Wang, H Zhu, LJ Hansen, ... Molecular Cancer Research 15 (5), 507-520, 2017 | 51 | 2017 |
| Signal integration and gene induction by a functionally distinct STAT3 phosphoform MS Waitkus, UM Chandrasekharan, B Willard, TL Tee, JK Hsieh, ... Molecular and cellular biology 34 (10), 1800-1811, 2014 | 47 | 2014 |
| Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition JT Low, V Chandramohan, ML Bowie, MC Brown, MS Waitkus, A Briley, ... Cancer Cell 40 (5), 439-440, 2022 | 46 | 2022 |
| Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities MS Waitkus, CJ Pirozzi, CJ Moure, BH Diplas, LJ Hansen, AB Carpenter, ... Cancer research 78 (1), 36-50, 2018 | 46 | 2018 |
| Sensitive and rapid detection of TERT promoter and IDH mutations in diffuse gliomas BH Diplas, H Liu, R Yang, LJ Hansen, AL Zachem, F Zhao, DD Bigner, ... Neuro-oncology 21 (4), 440-450, 2019 | 40 | 2019 |
| Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe Y Liu, AB Carpenter, CJ Pirozzi, H Yuan, MS Waitkus, Z Zhou, L Hansen, ... Nanotechnology 30 (27), 275101, 2019 | 33 | 2019 |
| Targeting mutant PPM1D sensitizes diffuse intrinsic pontine glioma cells to the PARP inhibitor olaparib Z Wang, C Xu, BH Diplas, CJ Moure, CPJ Chen, LH Chen, C Du, H Zhu, ... Molecular Cancer Research 18 (7), 968-980, 2020 | 27 | 2020 |
| CRISPR editing of mutant IDH1 R132H induces a CpG methylation-low state in patient-derived glioma models of G-CIMP CJ Moure, BH Diplas, LH Chen, R Yang, CJ Pirozzi, Z Wang, I Spasojevic, ... Molecular Cancer Research 17 (10), 2042-2050, 2019 | 25 | 2019 |
| Targeting isocitrate dehydrogenase mutations in cancer: emerging evidence and diverging strategies MS Waitkus, H Yan Clinical Cancer Research 27 (2), 383-388, 2021 | 22 | 2021 |
| Antitumor activity of a mitochondrial-targeted HSP90 inhibitor in gliomas S Wei, D Yin, S Yu, X Lin, MR Savani, K Du, Y Ku, D Wu, S Li, H Liu, ... Clinical Cancer Research 28 (10), 2180-2195, 2022 | 20 | 2022 |
| A modified nucleoside 6-Thio-2′-deoxyguanosine exhibits antitumor activity in gliomas S Yu, S Wei, M Savani, X Lin, K Du, I Mender, S Siteni, T Vasilopoulos, ... Clinical Cancer Research 27 (24), 6800-6814, 2021 | 20 | 2021 |
| Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2 UM Chandrasekharan, M Waitkus, CM Kinney, A Walters-Stewart, ... Arteriosclerosis, thrombosis, and vascular biology 30 (10), 1983-1989, 2010 | 20 | 2010 |
| STAT3-mediated coincidence detection regulates noncanonical immediate early gene induction MS Waitkus, UM Chandrasekharan, B Willard, SJ Haque, PE DiCorleto Journal of Biological Chemistry 288 (17), 11988-12003, 2013 | 18 | 2013 |
| Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression JD Boerckel, UM Chandrasekharan, MS Waitkus, EG Tillmaand, R Bartlett, ... Arteriosclerosis, thrombosis, and vascular biology 34 (5), 1020-1031, 2014 | 17 | 2014 |
| Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma JT Low, MC Brown, ZJ Reitman, JD Bernstock, JM Markert, GK Friedman, ... The Journal of Clinical Investigation 134 (2), 2024 | 14 | 2024 |