| Transcription factor NRF2 as a therapeutic target for chronic diseases: a systems medicine approach A Cuadrado, G Manda, A Hassan, MJ Alcaraz, C Barbas, A Daiber, ... Pharmacological reviews 70 (2), 348-383, 2018 | 628 | 2018 |
| Network-based in silico drug efficacy screening E Guney, J Menche, M Vidal, AL Barábasi Nature communications 7 (1), 10331, 2016 | 550 | 2016 |
| Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare D Cirillo, S Catuara-Solarz, C Morey, E Guney, L Subirats, S Mellino, ... NPJ digital medicine 3 (1), 1-11, 2020 | 458 | 2020 |
| Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 325 | 2019 |
| From single drug targets to synergistic network pharmacology in ischemic stroke AI Casas, AA Hassan, SJ Larsen, V Gomez-Rangel, M Elbatreek, ... Proceedings of the National Academy of Sciences 116 (14), 7129-7136, 2019 | 204 | 2019 |
| HotSprint: database of computational hot spots in protein interfaces E Guney, N Tuncbag, O Keskin, A Gursoy Nucleic acids research 36 (suppl_1), D662-D666, 2007 | 145 | 2007 |
| Exploiting protein-protein interaction networks for genome-wide disease-gene prioritization E Guney, B Oliva Public Library of Science 7 (9), e43557, 2012 | 136 | 2012 |
| Architectures and functional coverage of protein–protein interfaces N Tuncbag, A Gursoy, E Guney, R Nussinov, O Keskin Journal of molecular biology 381 (3), 785-802, 2008 | 130 | 2008 |
| Tissue specificity of human disease module M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ... Scientific reports 6 (1), 35241, 2016 | 117 | 2016 |
| Biana: a software framework for compiling biological interactions and analyzing networks J Garcia-Garcia, E Guney, R Aragues, J Planas-Iglesias, B Oliva BMC bioinformatics 11, 1-12, 2010 | 100 | 2010 |
| Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis SK Sieberts, F Zhu, J García-García, E Stahl, A Pratap, G Pandey, ... Nature communications 7 (1), 12460, 2016 | 97 | 2016 |
| Integrating personalized gene expression profiles into predictive disease-associated gene pools J Menche, E Guney, A Sharma, PJ Branigan, MJ Loza, F Baribaud, ... NPJ systems biology and applications 3 (1), 10, 2017 | 67 | 2017 |
| A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection F Langhauser, AI Casas, VTV Dao, E Guney, J Menche, E Geuss, ... NPJ systems biology and applications 4 (1), 8, 2018 | 58 | 2018 |
| Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer HB Engin, E Guney, O Keskin, B Oliva, A Gursoy PloS one 8 (11), e81035, 2013 | 51 | 2013 |
| A transcriptome-proteome integrated network identifies endoplasmic reticulum thiol oxidoreductase (ERp57) as a hub that mediates bone metastasis N Santana-Codina, R Carretero, R Sanz-Pamplona, T Cabrera, E Guney, ... Molecular & Cellular Proteomics 12 (8), 2111-2125, 2013 | 49 | 2013 |
| GUILDify: a web server for phenotypic characterization of genes through biological data integration and network-based prioritization algorithms E Guney, J Garcia-Garcia, B Oliva Bioinformatics 30 (12), 1789-1790, 2014 | 48 | 2014 |
| iFrag: a protein–protein interface prediction server based on sequence fragments J Garcia-Garcia, V Valls-Comamala, E Guney, D Andreu, FJ Muñoz, ... Journal of molecular biology 429 (3), 382-389, 2017 | 44 | 2017 |
| NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype MH Elbatreek, S Sadegh, E Anastasi, E Guney, C Nogales, T Kacprowski, ... PLoS Biology 18 (11), e3000885, 2020 | 42 | 2020 |
| Proximal pathway enrichment analysis for targeting comorbid diseases via network endopharmacology J Aguirre-Plans, J Piñero, J Menche, F Sanz, LI Furlong, HHHW Schmidt, ... Pharmaceuticals 11 (3), 61, 2018 | 42 | 2018 |
| Genetic and functional characterization of disease associations explains comorbidity C Rubio-Perez, E Guney, D Aguilar, J Piñero, J Garcia-Garcia, B Iadarola, ... Scientific Reports 7 (1), 6207, 2017 | 40 | 2017 |
Harald H.H.W. SchmidtProfessor & Chair of Pharmacology and Personalised Medicine, University of MaastrichtVerified email at maastrichtuniversity.nl