Robert P. Doyle PhD

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Jon ZubietaProfessor of Chemistry Syracuse UniversityVerified email at syr.edu
Matthew R HayesAlbert J. Stunkard Professor in Psychiatry, University of PennsylvaniaVerified email at mail.med.upenn.edu
Timothy FairchildAssociate Professor in Exercise Physiology, Murdoch UniversityVerified email at murdoch.edu.au
George G. HolzProfessor of Medicine and Pharmacology, SUNY Upstate Medical UniversityVerified email at upstate.edu
Bart C De JongheUniversity of PennsylvaniaVerified email at nursing.upenn.edu
Tito BornerUniversity of PennsylvaniaVerified email at nursing.upenn.edu
Paul E. KrugerProfessor of Chemistry, University of CanterburyVerified email at canterbury.ac.nz
Christian L RothProfessor of Pediatrics, University of Washington, SeattleVerified email at seattlechildrens.org
Nadia Marino, PhDDipartimento di Chimica e Tecnologie Chimiche, UnicalVerified email at unical.it
Clinton ElfersResearch Scientist, Seattle Children’s Research InstituteVerified email at seattlechildrens.org
Damian G. AllisDepartment of Chemistry, Syracuse UniversityVerified email at somewhereville.com
Susan Clardy-JamesHarvard Medical School/ Mass. General HospitalVerified email at syr.edu
Lauren M SteinUniversity of PennsylvaniaVerified email at mail.med.upenn.edu
Kylie S. Chichura, Ph.D.AlltrnaVerified email at alltrna.com
John BabichRatio TherapeuticsVerified email at ratiotx.com
Harvey GrillProfessor of Psychology and Neuroscience. University of PennsylvaniaVerified email at yale.edu
Kelly E HenryInvicroVerified email at invicro.com
Anna R. KahkoskaUniversity of North Carolina at Chapel HillVerified email at med.unc.edu
Christopher BoddyDepartment of Chemistry, University of OttawaVerified email at uottawa.ca
Ian SweetProfessor of Medicine, University of WashingtonVerified email at entoxsciences.com

Robert P. Doyle PhD

Jack and Laura H. Milton Professor. Chemistry, Syracuse University / Medicine SUNY Upstate

Verified email at syr.edu - Homepage

Medicinal Chemistry GPCR polyagonists GDF15 vitamin B12


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Challenges in the diagnosis of magnesium status JL Workinger, RP Doyle, J Bortz Nutrients 10 (9), 1202, 2018	260	2018
GDF15 induces anorexia through nausea and emesis T Borner, ED Shaulson, MY Ghidewon, AB Barnett, CC Horn, RP Doyle, ... Cell metabolism 31 (2), 351-362. e5, 2020	205	2020
The coordination chemistry of 1, 4, 7, 10-tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic acid (H4DOTA): Structural overview and analyses on structure–stability relationships N Viola-Villegas, RP Doyle Coordination Chemistry Reviews 253 (13-14), 1906-1925, 2009	188	2009
Traveling the Vitamin B₁₂ Pathway: Oral Delivery of Protein and Peptide Drugs AK Petrus, TJ Fairchild, RP Doyle Angewandte Chemie International Edition 48 (6), 1022-1028, 2009	177	2009
Vitamin B₁₂ in drug delivery: breaking through the barriers to a B₁₂ bioconjugate pharmaceutical SM Clardy, DG Allis, TJ Fairchild, RP Doyle Expert opinion on drug delivery 8 (1), 127-140, 2011	126	2011
Targeting the Folate Receptor (FR): Imaging and Cytotoxicity of Re^I Conjugates in FR‐Overexpressing Cancer Cells N Viola‐Villegas, AE Rabideau, J Cesnavicious, J Zubieta, RP Doyle ChemMedChem: Chemistry Enabling Drug Discovery 3 (9), 1387-1394, 2008	119	2008
Vitamin B₁₂ as a Carrier for the Oral Delivery of Insulin AK Petrus, AR Vortherms, TJ Fairchild, RP Doyle ChemMedChem: Chemistry Enabling Drug Discovery 2 (12), 1717-1721, 2007	99	2007
Targeting the Cubilin Receptor through the Vitamin B₁₂ Uptake Pathway: Cytotoxicity and Mechanistic Insight through Fluorescent Re(I) Delivery N Viola-Villegas, AE Rabideau, M Bartholoma, J Zubieta, RP Doyle Journal of medicinal chemistry 52 (16), 5253-5261, 2009	97	2009
A modular phase transfer and ligand exchange protocol for quantum dots J Zylstra, J Amey, NJ Miska, L Pang, CR Hine, J Langer, RP Doyle, ... Langmuir 27 (8), 4371-4379, 2011	86	2011
Synthesis, structure and thermal analysis of the gallium complex of 1, 4, 7, 10-tetraazacyclo-dodecane-N, N′, N ″, N‴-tetraacetic acid (DOTA) NA Viola, RS Rarig Jr, W Ouellette, RP Doyle Polyhedron 25 (18), 3457-3462, 2006	71	2006
Isostructural Pd^II and Pt^II Pyrophosphato Complexes: Polymorphism and Unusual Bond Character in d⁸−d⁸ Systems N Marino, CH Fazen, JD Blakemore, CD Incarvito, N Hazari, RP Doyle Inorganic Chemistry 50 (6), 2507-2520, 2011	66	2011
Coordination complexes incorporating pyrophosphate: Structural overview and exploration of their diverse magnetic, catalytic and biological properties OF Ikotun, N Marino, PE Kruger, M Julve, RP Doyle Coordination Chemistry Reviews 254 (7-8), 890-915, 2010	63	2010
Aging-related changes in the iron status of skeletal muscle KC DeRuisseau, YM Park, LR DeRuisseau, PM Cowley, CH Fazen, ... Experimental gerontology 48 (11), 1294-1302, 2013	61	2013
Pyrophosphate-bridged complexes with picomolar toxicity OF Ikotun, EM Higbee, W Ouellette, RP Doyle Journal of inorganic biochemistry 103 (9), 1254-1264, 2009	59	2009
Pyrophosphate-mediated magnetic interactions in Cu (II) coordination complexes N Marino, OF Ikotun, M Julve, F Lloret, J Cano, RP Doyle Inorganic chemistry 50 (1), 378-389, 2011	55	2011
A water soluble vitamin B 12-Re (i) fluorescent conjugate for cell uptake screens: use in the confirmation of cubilin in the lung cancer line A549 AR Vortherms, AR Kahkoska, AE Rabideau, J Zubieta, LL Andersen, ... Chemical Communications 47 (35), 9792-9794, 2011	54	2011
Single amino acid chelate complexes of the M(CO)₃⁺ core for correlating fluorescence and radioimaging studies (M = ^99mTc or Re) MP Coogan, RP Doyle, JF Valliant, JW Babich, J Zubieta Journal of Labelled Compounds and Radiopharmaceuticals 57 (4), 255-261, 2014	53	2014
Synthesis, characterization and pharmacodynamics of vitamin-B12-conjugated glucagon-like peptide-1 S Clardy-James, OG Chepurny, CA Leech, GG Holz, RP Doyle ChemMedChem 8 (4), 582, 2012	53	2012
Synthesis, cytotoxicity, and insight into the mode of action of Re (CO) 3 thymidine complexes MD Bartholomä, AR Vortherms, S Hillier, B Ploier, J Joyal, J Babich, ... ChemMedChem 5 (9), 1513-1529, 2010	49	2010
Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors OG Chepurny, RL Bonaccorso, CA Leech, T Wöllert, GM Langford, ... Scientific reports 8 (1), 3749, 2018	48	2018

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