Neuropilin-1 is a host factor for SARS-CoV-2 infection JL Daly, B Simonetti, K Klein, KE Chen, MK Williamson, C Antón-Plágaro, ... Science 370 (6518), 861-865, 2020 | 1328 | 2020 |
Towards a molecular understanding of endosomal trafficking by Retromer and Retriever KE Chen, MD Healy, BM Collins Traffic 20 (7), 465-478, 2019 | 172 | 2019 |
Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities M Chandra, YKY Chin, C Mas, JR Feathers, B Paul, S Datta, KE Chen, ... Nature communications 10 (1), 1528, 2019 | 140 | 2019 |
Drosophila Snazarus regulates a lipid droplet population at plasma membrane-droplet contacts in adipocytes R Ugrankar, J Bowerman, H Hariri, M Chandra, K Chen, MF Bossanyi, ... Developmental cell 50 (5), 557-572. e5, 2019 | 89 | 2019 |
Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide MP Christie, AE Whitten, GJ King, SH Hu, RJ Jarrott, KE Chen, AP Duff, ... Proceedings of the National Academy of Sciences 109 (25), 9816-9821, 2012 | 70 | 2012 |
Community-wide experimental evaluation of the PROSS stability-design method Y Peleg, R Vincentelli, BM Collins, KE Chen, EK Livingstone, ... Journal of molecular biology 433 (13), 166964, 2021 | 49 | 2021 |
Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome MD Healy, KE McNally, R Butkovič, M Chilton, K Kato, J Sacharz, ... Cell 186 (10), 2219-2237. e29, 2023 | 39 | 2023 |
Molecular basis for membrane recruitment by the PX and C2 domains of class II phosphoinositide 3-kinase-C2α KE Chen, VA Tillu, M Chandra, BM Collins Structure 26 (12), 1612-1625. e4, 2018 | 38 | 2018 |
The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer KE Chen, AA Richards, JK Ariffin, IL Ross, MJ Sweet, S Kellie, B Kobe, ... Acta Crystallographica Section D: Biological Crystallography 68 (6), 637-648, 2012 | 38 | 2012 |
Structural insights into the architecture and membrane interactions of the conserved COMMD proteins MD Healy, MK Hospenthal, RJ Hall, M Chandra, M Chilton, V Tillu, ... Elife 7, e35898, 2018 | 33 | 2018 |
SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling B Simonetti, Q Guo, M Giménez-Andrés, KE Chen, ERR Moody, AJ Evans, ... PLoS biology 20 (4), e3001601, 2022 | 28 | 2022 |
Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain–modulated complex formation KE Chen, SY Lin, MJ Wu, MR Ho, A Santhanam, CC Chou, TC Meng, ... Science signaling 7 (347), ra98-ra98, 2014 | 25 | 2014 |
Antó n-Plá garo JL Daly, B Simonetti, K Klein, KE Chen, MK Williamson C., Shoemark, DK, Simó n-Gracia, L., Bauer, M., Hollandi, R., et al, 861-865, 2020 | 24 | 2020 |
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex KE Chen, Q Guo, TA Hill, Y Cui, AK Kendall, Z Yang, RJ Hall, MD Healy, ... Science advances 7 (49), eabg4007, 2021 | 22 | 2021 |
The 1.2 Å resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production PM Walden, B Heras, KE Chen, MA Halili, K Rimmer, P Sharma, ... Acta Crystallographica Section D: Biological Crystallography 68 (10), 1290-1302, 2012 | 22 | 2012 |
Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases KE Chen, MY Li, CC Chou, MR Ho, GC Chen, TC Meng, AHJ Wang Structure 23 (4), 653-664, 2015 | 19 | 2015 |
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system Y Wu, Z Cui, YH Huang, SJ de Veer, AV Aralov, Z Guo, SV Moradi, ... Nature Communications 13 (1), 260, 2022 | 15 | 2022 |
The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized KE Chen, AA Richards, TT Caradoc-Davies, PR Vajjhala, G Robin, ... Acta Crystallographica Section D: Biological Crystallography 69 (5), 774-784, 2013 | 12 | 2013 |
Backbone resonance assignments of the monomeric DUF59 domain of human Fam96a C Mas, KE Chen, IM Brereton, JL Martin, JM Hill Biomolecular NMR assignments 7, 117-120, 2013 | 10 | 2013 |
Mechanistic basis for SNX27-Retromer coupling to ESCPE-1 in promoting endosomal cargo recycling B Simonetti, Q Guo, M Gimenez-Andres, KE Chen, ERR Moody, AJ Evans, ... bioRxiv, 2021.08. 28.457928, 2021 | 7 | 2021 |