| Direct protein-lipid interactions shape the conformational landscape of secondary transporters C Martens, M Shekhar, AJ Borysik, AM Lau, E Reading, E Tajkhorshid, ... Nature communications 9 (1), 4151, 2018 | 140 | 2018 |
| Lipids modulate the conformational dynamics of a secondary multidrug transporter C Martens, RA Stein, M Masureel, A Roth, S Mishra, R Dawaliby, ... Nature Structural & Molecular Biology, 2016 | 120 | 2016 |
| Direct activation of a bacterial innate immune system by a viral capsid protein T Zhang, H Tamman, K Coppieters’t Wallant, T Kurata, M LeRoux, ... Nature 612 (7938), 132-140, 2022 | 117 | 2022 |
| Interrogating membrane protein conformational dynamics within native lipid compositions E Reading, Z Hall, C Martens, T Haghighi, H Findlay, Z Ahdash, A Politis, ... Angewandte Chemie International Edition 56 (49), 15654-15657, 2017 | 114 | 2017 |
| Protonation drives the conformational switch in the multidrug transporter LmrP M Masureel, C Martens, RA Stein, S Mishra, JM Ruysschaert, ... Nature chemical biology 10 (2), 149-155, 2014 | 90 | 2014 |
| Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry AMC Lau, Z Ahdash, C Martens, A Politis Bioinformatics 35 (17), 3171-3173, 2019 | 68 | 2019 |
| An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity V Debruycker, A Hutchin, M Masureel, E Ficici, C Martens, P Legrand, ... Nature structural & molecular biology 27 (9), 829-835, 2020 | 67 | 2020 |
| Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome SV Faull, AMC Lau, C Martens, Z Ahdash, K Hansen, H Yebenes, ... Nature communications 10 (1), 3814, 2019 | 62 | 2019 |
| Integrating hydrogen–deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins C Martens, M Shekhar, AM Lau, E Tajkhorshid, A Politis Nature protocols 14 (11), 3183-3204, 2019 | 59 | 2019 |
| Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter R Jia, C Martens, M Shekhar, S Pant, GA Pellowe, AM Lau, HE Findlay, ... Nature communications 11 (1), 6162, 2020 | 46 | 2020 |
| A glimpse into the molecular mechanism of integral membrane proteins through hydrogen–deuterium exchange mass spectrometry C Martens, A Politis Protein science 29 (6), 1285-1301, 2020 | 46 | 2020 |
| A topological switch in CFTR modulates channel activity and sensitivity to unfolding D Scholl, M Sigoillot, M Overtus, RC Martinez, C Martens, Y Wang, ... Nature chemical biology 17 (9), 989-997, 2021 | 18 | 2021 |
| Assessing the role of lipids in the molecular mechanism of membrane proteins L Jodaitis, T Van Oene, C Martens International journal of molecular sciences 22 (14), 7267, 2021 | 17 | 2021 |
| A polyamine acetyltransferase regulates the motility and biofilm formation of Acinetobacter baumannii J Armalytė, A Čepauskas, G Šakalytė, J Martinkus, J Skerniškytė, ... Nature communications 14 (1), 3531, 2023 | 16 | 2023 |
| Linking function to global and local dynamics in an elevator-type transporter D Ciftci, C Martens, VG Ghani, SC Blanchard, A Politis, GHM Huysmans, ... Proceedings of the National Academy of Sciences 118 (49), e2025520118, 2021 | 13 | 2021 |
| The structure of DarB in complex with RelNTD reveals nonribosomal activation of Rel stringent factors A Ainelo, J Caballero-Montes, O Bulvas, K Ernits, K Coppieters ‘t Wallant, ... Science advances 9 (3), eade4077, 2023 | 9 | 2023 |
| Analyzing protein architectures and protein-ligand complexes by integrative structural mass spectrometry Z Ahdash, AM Lau, C Martens, A Politis Journal of Visualized Experiments: JoVE, 57966, 2018 | 7 | 2018 |
| Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems T Mets, T Kurata, K Ernits, MJO Johansson, SZ Craig, GM Evora, ... Cell Host & Microbe, 2024 | 6 | 2024 |
| Hydrogen-deuterium exchange coupled to mass spectrometry: A multifaceted tool to decipher the molecular mechanism of transporters K Coppieters't Wallant, C Martens Biochimie 205, 95-101, 2023 | 4 | 2023 |
| A bacterial immunity protein directly senses two disparate phage proteins T Zhang, A Cepauskas, A Nadieina, A Thureau, K Coppieters ‘t Wallant, ... Nature, 1-8, 2024 | 3 | 2024 |
Argyris PolitisGroup Leader, EPSRC Research Fellow, University of ManchesterVerified email at manchester.ac.uk