| Regulation of G protein βγ signaling K Senarath, D Kankanamge, S Samaradivakara, K Ratnayake, ... International review of cell and molecular biology 339, 133-191, 2018 | 53 | 2018 |
| Subtype-dependent regulation of Gβγ signalling M Tennakoon, K Senarath, D Kankanamge, K Ratnayake, D Wijayaratna, ... Cellular signalling 82, 109947, 2021 | 47 | 2021 |
| Gγ identity dictates efficacy of Gβγ signaling and macrophage migration K Senarath, JL Payton, D Kankanamge, P Siripurapu, M Tennakoon, ... Journal of Biological Chemistry 293 (8), 2974-2989, 2018 | 46 | 2018 |
| G protein gamma subunit, a hidden master regulator of GPCR signaling D Kankanamge, M Tennakoon, A Karunarathne, N Gautam Journal of Biological Chemistry 298 (12), 2022 | 35 | 2022 |
| Dissociation of the G protein βγ from the Gq–PLCβ complex partially attenuates PIP2 hydrolysis D Kankanamge, S Ubeysinghe, M Tennakoon, PD Pantula, K Mitra, L Giri, ... Journal of Biological Chemistry 296, 2021 | 35 | 2021 |
| Two independent but synchronized Gβγ subunit–controlled pathways are essential for trailing-edge retraction during macrophage migration P Siripurapu, D Kankanamge, K Ratnayake, K Senarath, A Karunarathne Journal of Biological Chemistry 292 (42), 17482-17495, 2017 | 28 | 2017 |
| Melanopsin (Opn4) utilizes Gαi and Gβγ as major signal transducers D Kankanamge, K Ratnayake, S Samaradivakara, A Karunarathne Journal of Cell Science 131 (11), jcs212910, 2018 | 25 | 2018 |
| Statins perturb Gβγ signaling and cell behavior in a Gγ subtype dependent manner M Tennakoon, D Kankanamge, K Senarath, Z Fasih, A Karunarathne Molecular pharmacology 95 (4), 361-375, 2019 | 20 | 2019 |
| G protein αq exerts expression level-dependent distinct signaling paradigms D Kankanamge, M Tennakoon, A Weerasinghe, L Cedeno-Rosario, ... Cellular signalling 58, 34-43, 2019 | 17 | 2019 |
| Optical approaches for single-cell and subcellular analysis of GPCR–G protein signaling D Kankanamge, K Ratnayake, K Senarath, M Tennakoon, E Harmon, ... Analytical and bioanalytical chemistry 411, 4481-4508, 2019 | 16 | 2019 |
| G protein γ (Gγ) subtype dependent targeting of GRK2 to M3 receptor by Gβγ S Samaradivakara, D Kankanamge, K Senarath, K Ratnayake, ... Biochemical and biophysical research communications 503 (1), 165-170, 2018 | 13 | 2018 |
| Comparison of calcium dynamics and specific features for G protein–coupled receptor–targeting drugs using live cell imaging and automated analysis RK Gupta, S Swain, D Kankanamge, PD Priyanka, R Singh, K Mitra, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (7), 848-858, 2017 | 12 | 2017 |
| A short C-terminal peptide in Gγ regulates Gβγ signaling efficacy M Tennakoon, K Senarath, D Kankanamge, DN Chadee, A Karunarathne Molecular biology of the cell 32 (16), 1446-1458, 2021 | 9 | 2021 |
| Measurement of GPCR-G protein activity in living cells K Ratnayake, D Kankanamge, K Senarath, P Siripurapu, N Weis, ... Methods in cell biology 142, 1-25, 2017 | 9 | 2017 |
| Spatiotemporal optical control of Gαq-PLCβ interactions S Ubeysinghe, D Kankanamge, W Thotamune, D Wijayaratna, ... ACS Synthetic Biology 13 (1), 242-258, 2023 | 8 | 2023 |
| Molecular regulation of PLCβ signaling S Ubeysinghe, D Wijayaratna, D Kankanamge, A Karunarathne Methods in Enzymology 682, 17-52, 2023 | 8 | 2023 |
| The spatial distribution of GPCR and Gβγ activity across a cell dictates PIP3 dynamics D Wijayaratna, K Ratnayake, S Ubeysinghe, D Kankanamge, ... Scientific Reports 13 (1), 2771, 2023 | 7 | 2023 |
| AGS3-based optogenetic GDI induces GPCR-independent Gβγ signalling and macrophage migration W Thotamune, S Ubeysinghe, C Rajarathna, D Kankanamge, ... Open Biology 15 (2), 240181, 2025 | | 2025 |
| AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration W Thotamune, S Ubeysinghe, C Rajarathna, D Kankanamge, ... bioRxiv, 2024.06. 04.597473, 2024 | | 2024 |
| Subcellular Optogenetic Inhibition of PLCβ-GαqGTP Interaction Sheds Light on the Molecular Regulation of Gαq-Governed Directional Cell Migration S Ubeysinghe, D Kankanamge, A Karunarathne Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
Ajith KarunarathneThe University of ToledoVerified email at utoledo.edu
